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Text
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URL Address
<a href="http://doi.org/10.7150/thno.22502" target="_blank" rel="noreferrer noopener">http://doi.org/10.7150/thno.22502</a>
Pages
1678–1689
Issue
6
Volume
8
Dublin Core
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Title
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Surface Enhanced Raman Spectroscopy (SERS) for the Multiplex Detection of Braf, Kras, and Pik3ca Mutations in Plasma of Colorectal Cancer Patients.
Publisher
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Theranostics
Date
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2018
1905-07
Subject
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Adult; Female; Humans; Male; Middle Aged; Aged; *colorectal cancer; *gene; *mutation; *Mutation; *PCR; *surface enhanced Raman scattering; Class I Phosphatidylinositol 3-Kinases/blood/*genetics; Cluster Analysis; Colorectal Neoplasms/blood/*diagnosis/genetics/pathology; DNA Primers/chemistry; Exons; Multiplex Polymerase Chain Reaction/methods/standards; Neoplasm Staging; Proto-Oncogene Proteins B-raf/blood/*genetics; Proto-Oncogene Proteins p21(ras)/blood/*genetics; Biomarkers; Spectrum Analysis; Raman/methods/*standards; Tumor/blood/*genetics
Creator
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Li Xiaozhou; Yang Tianyue; Li Caesar Siqi; Song Youtao; Lou Hong; Guan Dagang; Jin Lili
Description
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In this paper, we discuss the use of a procedure based on polymerase chain reaction (PCR) and surface enhanced Raman spectroscopy (SERS) (PCR-SERS) to detect DNA mutations. Methods: This method was implemented by first amplifying
Identifier
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<a href="http://doi.org/10.7150/thno.22502" target="_blank" rel="noreferrer noopener">10.7150/thno.22502</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*colorectal cancer
*gene
*Mutation
*PCR
*surface enhanced Raman scattering
2018
Adult
Aged
Biomarkers
Class I Phosphatidylinositol 3-Kinases/blood/*genetics
Cluster Analysis
Colorectal Neoplasms/blood/*diagnosis/genetics/pathology
DNA Primers/chemistry
Exons
Female
Guan Dagang
Humans
Jin Lili
Li Caesar Siqi
Li Xiaozhou
Lou Hong
Male
Middle Aged
Multiplex Polymerase Chain Reaction/methods/standards
Neoplasm Staging
Proto-Oncogene Proteins B-raf/blood/*genetics
Proto-Oncogene Proteins p21(ras)/blood/*genetics
Raman/methods/*standards
Song Youtao
Spectrum Analysis
Theranostics
Tumor/blood/*genetics
Yang Tianyue