Browse Items (4 total)
- Tags: Punicaceae/*chemistry
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-kappaB and Nrf2 Signaling Pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/toxicity, 2017, 9, Animal Studies, Animals, Anti-Inflammatory Agents/*pharmacology, anti-inflammatory effects, Anticarcinogenic Agents/pharmacology, Apoptosis/drug effects, Bhatia Deepak, Bishayee Anupam, Breast Neoplasms, breast tumor, Cell Transformation, Chemoprevention, COX-2, Cyclooxygenase 2/genetics/metabolism, DMBA, Dose-Response Relationship, Drug, Experimental/*prevention & control, Female, Gene Expression Regulation, HSP90, HSP90 Heat-Shock Proteins/genetics/metabolism, I-kappa B Kinase/genetics/metabolism, Inflammation Mediators, Mammary Neoplasms, Mandal Animesh, Neoplasms – Prevention and Control, Neoplastic, Neoplastic/drug effects, NF-E2-Related Factor 2/genetics/*metabolism, NF-kappa B/genetics/*metabolism, NF-kappaB, Nrf2, Nutrients, Physical Education and Training, Plant Preparations/*pharmacology, Pomegranate, Punica granatum, Punicaceae/*chemistry, Rats, Signal Transduction
Mechanism of Breast Cancer Preventive Action of Pomegranate: Disruption of Estrogen Receptor and Wnt/beta-Catenin Signaling Pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/pharmacology, 2015, 9, Animals, Anticarcinogenic Agents/*pharmacology, beta Catenin/*metabolism, beta-catenin, Bishayee Anupam, Breast Neoplasms/*drug therapy/metabolism, Cell Proliferation/drug effects, Cell Transformation, Chemoprevention/methods, Cyclin D1, DMBA, Down-Regulation/drug effects, Estrogen Receptor alpha/metabolism, estrogen receptors, Estrogen/*metabolism, Female, mammary tumorigenesis, Mandal Animesh, Molecules (Basel, Switzerland), Neoplastic/drug effects/metabolism, pomegranate (Punica granatum L.), Punicaceae/*chemistry, Rats, Receptors, Sprague-Dawley, Wnt Proteins/*metabolism, Wnt Signaling Pathway/*drug effects
Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms.
Tags: *Phytotherapy, 2011, Alkylating Agents/toxicity, Animals, Antioxidants/*therapeutic use, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinogenesis, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Experimental/chemically induced/*drug therapy/metabolism, GA-Binding Protein Transcription Factor/*metabolism, gamma-Glutamyltransferase/metabolism, Hepatocellular/chemically induced/*drug therapy/metabolism, Immunoenzyme Techniques, Lansky Ephraim P, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, NEOMED College of Pharmacy, Nevo Eviatar, Oxidative Stress, Plant Extracts/*therapeutic use, Punicaceae/*chemistry, Rats, Sprague-Dawley, Thoppil Roslin J, Western
A Polyphenol-rich Pomegranate Fruit Extract Suppresses NF-kappaB and IL-6 Expression by Blocking the Activation of IKKbeta and NIK in Primary Human Chondrocytes.
Tags: 2017, Ashruf Omer S, Chondrocytes, Chondrocytes – Drug Effects, Chondrocytes/drug effects, Department of Anatomy & Neurobiology, Fruit, Fruit/chemistry, Gene Expression Regulation/drug effects, Genes – Drug Effects, Haqqi Tariq M, Haseeb Abdul, Humans, I-kappa B Kinase/genetics/*metabolism, IkappaB, IKKbeta, IL-1beta, Interleukin 1 – Metabolism, Interleukin-1beta/metabolism, Interleukin-6/genetics/*metabolism, Interleukins, Interleukins – Metabolism, Khan Nazir M, NEOMED College of Medicine, NF-kappa B, NF-kappa B – Metabolism, NF-kappa B/genetics/*metabolism, NF-kappaB, NIK, Osteoarthritis, Phosphorylation – Drug Effects, Phosphorylation/drug effects, Phytotherapy research : PTR, Plant Extracts, Plant Extracts – Pharmacodynamics, Plant Extracts/chemistry/*pharmacology, Polyphenols – Pharmacodynamics, Polyphenols/pharmacology, Pomegranate, Protein-Serine-Threonine Kinases/genetics/*metabolism, Proteins – Metabolism, Punicaceae/*chemistry, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Transcription Factor RelA/metabolism, Transferases, Transferases – Metabolism