2
40
45
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.ajem.2014.10.030" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ajem.2014.10.030</a>
Pages
456–458
Issue
3
Volume
33
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Evaluation of ED patient and visitor understanding of living wills and do-not-resuscitate orders.
Publisher
An entity responsible for making the resource available
The American journal of emergency medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
2015-03
Subject
The topic of the resource
*Emergency Service; *Health Knowledge; *Living Wills; *Resuscitation Orders; *Visitors to Patients; 80 and over; 80 and Over; Aged; Attitude to Health; Attitudes; Emergency Service; Hospital; Humans; Living Wills; Practice; Questionnaires; Resuscitation Orders; Surveys and Questionnaires; Visitors to Patients
Creator
An entity primarily responsible for making the resource
Bhalla Mary Colleen; Ruhlin Michael U; Frey Jennifer A; Wilber Scott T
Identifier
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<a href="http://doi.org/10.1016/j.ajem.2014.10.030" target="_blank" rel="noreferrer noopener">10.1016/j.ajem.2014.10.030</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Emergency Service
*Health Knowledge
*Living Wills
*Resuscitation Orders
*Visitors to Patients
2015
80 and over
Aged
Attitude to Health
Attitudes
Bhalla Mary Colleen
Department of Emergency Medicine
Emergency Service
Frey Jennifer A
Hospital
Humans
Living Wills
NEOMED College of Medicine
Practice
Questionnaires
Resuscitation Orders
Ruhlin Michael U
Surveys and Questionnaires
The American journal of emergency medicine
Visitors to Patients
Wilber Scott T
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s11136-017-1745-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s11136-017-1745-8</a>
Pages
1089–1098
Issue
4
Volume
27
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Minimal clinically important differences in the EORTC QLQ-C30 and brief pain inventory in patients undergoing re-irradiation for painful bone metastases.
Publisher
An entity responsible for making the resource available
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-04
Subject
The topic of the resource
*Bone metastases; *Brief pain inventory; *EORTC QLQ-C30; *Minimal Clinically Important Difference; *Minimal clinically important differences; *Radiation; 80 and over; 80 and Over; Adolescence; Adolescent; Adult; Aged; Bone Metastases – Radiotherapy; BONE metastasis; BONE metastasis – Treatment; Bone Neoplasms/*complications/radiotherapy/secondary; Brief Pain Inventory; BRIEF Pain Inventory; Cancer Patients; CANCER patients; CANCER radiotherapy; Clinical Assessment Tools; Female; Funding Source; Human; Humans; Instrument Scaling; LONGITUDINAL method; Male; Middle Age; Middle Aged; Pain Management; PAIN management; Pain/*diagnosis; Prospective Studies; Quality of Life/*psychology; Questionnaires; QUESTIONNAIRES; RANDOMIZED controlled trials; Re-Irradiation/*adverse effects; REOPERATION; Repeat Procedures; RESEARCH funding; SCALING (Social sciences); Secondary Analysis; SECONDARY analysis; Surveys and Questionnaires; Young Adult
Creator
An entity primarily responsible for making the resource
Raman Srinivas; Ding Keyue; Chow Edward; Meyer Ralph M; van der Linden Yvette M; Roos Daniel; Hartsell William F; Hoskin Peter; Wu Jackson S Y; Nabid Abdenour; Haas Rick; Wiggenraad Ruud; Babington Scott; Demas William F; Wilson Carolyn F; Wong Rebecca K S; Zhu Liting; Brundage Michael
Description
An account of the resource
PURPOSE: The EORTC QLQ-C30 and the Brief Pain Inventory (BPI) are validated tools for measuring quality of life (QOL) and the impact of pain in patients with advanced cancer. Interpretation of these instrument scores can be challenging and it is difficult to know what numerical changes translate to clinically significant impact in patients' lives. To address this issue, our study sought to establish the minimal clinically important differences (MCID) for these two instruments in a prospective cohort of patients with advanced cancer and painful bone metastases. METHODS: Both anchor-based and distribution-based methods were used to estimate the MCID scores from patients enrolled in a randomized phase III trial evaluating two different re-irradiation treatment schedules. For the anchor-based method, the global QOL item from the QLQ-C30 was chosen as the anchor. Spearman correlation coefficients were calculated for all items and only those items with moderate or better correlation (\textbarr\textbar \textgreater/= 0.30) with the anchor were used for subsequent analysis. A 10-point difference in the global QOL score was used to classify improvement and deterioration, and the MCID scores were calculated for each of these categories. These results were compared with scores obtained by the distribution-method, which estimates the MCID purely from the statistical characteristics of the sample population. RESULTS: A total of 375 patients were included in this study with documented pain responses and completed QOL questionnaires at 2 months. 9/14 items in the QLQ-C30 and 6/10 items in the BPI were found to have moderate or better correlation with the anchor. For deterioration, statistically significant MCID scores were found in all items of the QLQ-C30 and BPI. For improvement, statistically significant MCID scores were found in 7/9 items of the QLQ-C30 and 2/6 items of the BPI. The MCID scores for deterioration were uniformly higher than the MCIDs for improvement. Using the distribution-based method, there was good agreement between the 0.5 standard deviation (SD) values and anchor-based scores for deterioration. For improvement, there was less agreement and the anchor-based scores were lower than the 0.5 SD values obtained from the distribution-based method. CONCLUSION: We present MCID scores for the QLQ-C30 and BPI instruments obtained from a large cohort of patients with advanced cancer undergoing re-irradiation for painful bone metastases. The results from this study were compared to other similar studies which showed larger MCID scores for improvement compared to deterioration. We hypothesize that disease trajectory and patient expectations are important factors in understanding the contrasting results. The results of this study can guide clinicians and researchers in the interpretation of these instruments.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s11136-017-1745-8" target="_blank" rel="noreferrer noopener">10.1007/s11136-017-1745-8</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Bone metastases
*Brief pain inventory
*EORTC QLQ-C30
*Minimal Clinically Important Difference
*Minimal clinically important differences
*Radiation
2018
80 and over
Adolescence
Adolescent
Adult
Aged
Babington Scott
Bone Metastases – Radiotherapy
BONE metastasis
BONE metastasis – Treatment
Bone Neoplasms/*complications/radiotherapy/secondary
Brief pain inventory
Brundage Michael
Cancer Patients
CANCER radiotherapy
Chow Edward
Clinical Assessment Tools
Demas William F
Ding Keyue
Female
Funding Source
Haas Rick
Hartsell William F
Hoskin Peter
Human
Humans
Instrument Scaling
LONGITUDINAL method
Male
Meyer Ralph M
Middle Age
Middle Aged
Nabid Abdenour
Pain Management
Pain/*diagnosis
Prospective Studies
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Quality of Life/*psychology
Questionnaires
Raman Srinivas
RANDOMIZED controlled trials
Re-Irradiation/*adverse effects
Reoperation
Repeat Procedures
RESEARCH funding
Roos Daniel
SCALING (Social sciences)
Secondary Analysis
Surveys and Questionnaires
van der Linden Yvette M
Wiggenraad Ruud
Wilson Carolyn F
Wong Rebecca K S
Wu Jackson S Y
Young Adult
Zhu Liting
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00520-015-2957-5" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00520-015-2957-5</a>
Pages
1617–1623
Issue
4
Volume
24
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Revisiting classification of pain from bone metastases as mild, moderate, or severe based on correlation with function and quality of life.
Publisher
An entity responsible for making the resource available
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-04
Subject
The topic of the resource
*Quality of Life; *Severity of Illness Index; 80 and over; 80 and Over; Adolescence; Adolescent; Adult; Aged; Bone metastases; Bone Neoplasms; Bone Neoplasms – Complications; Bone Neoplasms/*complications/secondary; Brief Pain Inventory; Female; Functional interference; Funding Source; Human; Humans; Male; Middle Age; Middle Aged; Pain – Classification; Pain – Etiology; Pain Measurement – Methods; Pain Measurement/*methods; Pain severity; Pain/*classification/etiology; Quality of life; Quality of Life; Questionnaires; Re-irradiation; Severity of Illness Indices; Survival; Young Adult
Creator
An entity primarily responsible for making the resource
Chow Edward; Ding Keyue; Parulekar Wendy R; Wong Rebecca K S; van der Linden Yvette M; Roos Daniel; Hartsell William F; Hoskin Peter; Wu Jackson S Y; Nabid Abdenour; Ong Francisca; van Tienhoven Geertjan; Babington Scott; Demas William F; Wilson Carolyn F; Brundage Michael; Zhu Liting; Meyer Ralph M
Description
An account of the resource
PURPOSE: The objective of our study was to determine the optimal cut points for classification of pain scores as mild, moderate, and severe based on interference with function and quality of life (QOL). METHODS: We evaluated 822 patients who completed the Brief Pain Inventory (BPI) and/or the European Organization for Research and Treatment of Cancer (EORTC) QOL Questionnaire Core 30 (QLQ-C30) prior to receiving repeat radiation therapy for previously irradiated painful bone metastases. Optimal cut points for mild, moderate, and severe pain were determined by the MANOVA that yielded the largest F ratio for the between category effect on the seven interference items of BPI and the six functional domains of QOL (physical, role, emotional, cognitive, social functioning, and global QOL) as indicated by Pillai's Trace, Wilk's lambda, and Hostelling's Trace F statistics. RESULTS: For BPI and for QOL domains separately, the two largest F ratios for Wilk's lambda, Pillai's Trace, and Hotelling's Trace F statistics were from the cut points 4, 8 and 6, 8. When combining both, the optimal cut points were 4, 8 with 1-4 (mild), 5-8 (moderate), and 9-10 (severe). With this classification, the mean scores of all the seven interference items in BPI and the six functional domains were all highly statistically different. Patients with severe pain survived significantly shorter than those with mild and moderate pain (p \textless 0.0001). CONCLUSION: Our analysis supports the classification of pain scores as follows: 1-4 as mild pain, 5-8 as moderate pain, and 9-10 as severe pain. This may facilitate conduct of future clinical trials.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00520-015-2957-5" target="_blank" rel="noreferrer noopener">10.1007/s00520-015-2957-5</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Quality of Life
*Severity of Illness Index
2016
80 and over
Adolescence
Adolescent
Adult
Aged
Babington Scott
Bone metastases
Bone Neoplasms
Bone Neoplasms – Complications
Bone Neoplasms/*complications/secondary
Brief pain inventory
Brundage Michael
Chow Edward
Demas William F
Ding Keyue
Female
Functional interference
Funding Source
Hartsell William F
Hoskin Peter
Human
Humans
Male
Meyer Ralph M
Middle Age
Middle Aged
Nabid Abdenour
Ong Francisca
Pain – Classification
Pain – Etiology
Pain Measurement – Methods
Pain Measurement/*methods
Pain severity
Pain/*classification/etiology
Parulekar Wendy R
Quality of Life
Questionnaires
Re-irradiation
Roos Daniel
Severity of Illness Indices
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Survival
van der Linden Yvette M
van Tienhoven Geertjan
Wilson Carolyn F
Wong Rebecca K S
Wu Jackson S Y
Young Adult
Zhu Liting
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00455-018-9881-z" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00455-018-9881-z</a>
Pages
627–635
Issue
5
Volume
33
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Maturation of the Coordination Between Respiration and Deglutition with and Without Recurrent Laryngeal Nerve Lesion in an Animal Model.
Publisher
An entity responsible for making the resource available
Dysphagia
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-10
Subject
The topic of the resource
*Animal model; *Deglutition; *Development; *Infant; *Recurrent laryngeal nerve; *Respiration; *Sensorimotor; Animal; Animal Population Groups; Animals; Biological; Deglutition – Physiology; Deglutition Disorders; Deglutition/*physiology; Disease Models; Humans; Laryngeal Nerves – Injuries; Laryngeal Nerves – Physiology; Larynx – Physiology; Larynx/*physiology; Models; Newborn; Questionnaires; Recurrent Laryngeal Nerve Injuries/*complications; Recurrent Laryngeal Nerve/physiology; Respiration; Swine
Creator
An entity primarily responsible for making the resource
Ballester Ashley; Gould Francois; Bond Laura; Stricklen Bethany; Ohlemacher Jocelyn; Gross Andrew; DeLozier Katherine R; Buddington Randall; Buddington Karyl; Danos Nicole; German Rebecca
Description
An account of the resource
The timing of the occurrence of a swallow in a respiratory cycle is critical for safe swallowing, and changes with infant development. Infants with damage to the recurrent laryngeal nerve, which receives sensory information from the larynx and supplies the intrinsic muscles of the larynx, experience a significant incidence of dysphagia. Using our validated infant pig model, we determined the interaction between this nerve damage and the coordination between respiration and swallowing during postnatal development. We recorded 23 infant pigs at two ages (neonatal and older, pre-weaning) feeding on milk with barium using simultaneous high-speed videofluoroscopy and measurements of thoracic movement. With a complete linear model, we tested for changes with maturation, and whether these changes are the same in control and lesioned individuals. We found (1) the timing of swallowing and respiration coordination changes with maturation; (2) no overall effect of RLN lesion on the timing of coordination, but (3) a greater magnitude of maturational change occurs with RLN injury. We also determined that animals with no surgical intervention did not differ from animals that had surgery for marker placement and a sham procedure for nerve lesion. The coordination between respiration and swallowing changes in normal, intact individuals to provide increased airway protection prior to weaning. Further, in animals with an RLN lesion, the maturation process has a larger effect. Finally, these results suggest a high level of brainstem sensorimotor interactions with respect to these two functions.
Identifier
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<a href="http://doi.org/10.1007/s00455-018-9881-z" target="_blank" rel="noreferrer noopener">10.1007/s00455-018-9881-z</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Animal model
*Deglutition
*Development
*Infant
*Recurrent laryngeal nerve
*Respiration
*Sensorimotor
2018
Animal
Animal Population Groups
Animals
Ballester Ashley
Biological
Bond Laura
Buddington Karyl
Buddington Randall
Danos Nicole
Deglutition – Physiology
Deglutition disorders
Deglutition/*physiology
DeLozier Katherine R
Department of Anatomy & Neurobiology
Disease Models
Dysphagia
German Rebecca
Gould Francois
Gross Andrew
Humans
Laryngeal Nerves – Injuries
Laryngeal Nerves – Physiology
Larynx – Physiology
Larynx/*physiology
Models
NEOMED College of Medicine
Newborn
Ohlemacher Jocelyn
Questionnaires
Recurrent Laryngeal Nerve Injuries/*complications
Recurrent Laryngeal Nerve/physiology
Respiration
Stricklen Bethany
Swine
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00455-017-9832-0" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00455-017-9832-0</a>
Pages
51–62
Issue
1
Volume
33
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
LVC Timing in Infant Pig Swallowing and the Effect of Safe Swallowing.
Publisher
An entity responsible for making the resource available
Dysphagia
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-02
Subject
The topic of the resource
*Animal model; *Aspiration; *Deglutition; *Deglutition disorders; *Dysphagia; *Infant; *Laryngeal vestibule closure; *Recurrent laryngeal nerve; Animal; Animal Population Groups; Animals; Aspiration – Etiology; Aspiration/*etiology; Biological; Deglutition – Physiology; Deglutition Disorders – Etiology; Deglutition Disorders/*etiology; Deglutition/*physiology; Disease Models; Humans; Laryngeal Nerve Injuries/*complications; Laryngeal Nerves – Injuries; Larynx; Models; Newborn; Oropharynx; Pneumonia; Questionnaires; Swine
Creator
An entity primarily responsible for making the resource
Gross Andrew; Ohlemacher Jocelyn; German Rebecca; Gould Francois
Description
An account of the resource
Recurrent laryngeal nerve (RLN) injury in neonates, a complication of head and neck surgeries, leads to increased aspiration risk and swallowing dysfunction. The severity of resulting sequelae range from morbidity, such as aspiration pneumonia, to mortality from infection and failure to thrive. The timing of airway protective events including laryngeal vestibule closure (LVC) is implicated in aspiration. We unilaterally transected the RLN in an infant pig model to observe changes in the timing of swallowing kinematics with lesion and aspiration. We recorded swallows using high-speed video-fluoroscopic swallow studies (VFSS) and scored them using the Infant Mammalian Penetration and Aspiration Scale (IMPAS). We hypothesized that changes would occur in swallowing kinematics (1) between RLN lesion and control animals, and (2) among safe swallows (IMPAS 1), penetration swallows (IMPAS 3), and aspiration swallows (IMPAS 7). We observed numerous changes in timing following RLN lesion in safe and unsafe swallows, suggesting pervasive changes in the coordination of oropharyngeal function. The timing of LVC, posterior tongue, and hyoid movements differed between pre- and post-lesion in safe swallows. Posterior tongue kinematics differed for post-lesion swallows with penetration. The timing and duration of LVC and posterior tongue movement differed between aspiration swallows pre- and post-lesion. After lesion, safe swallows and swallows with aspiration differed in timing of LVC, laryngeal vestibule opening, and posterior tongue and hyoid movements. The timing of thyrohyoid muscle activity varied with IMPAS, but not lesion. Further study into the pathophysiology of RLN lesion-induced swallowing dysfunction is important to developing novel therapies.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00455-017-9832-0" target="_blank" rel="noreferrer noopener">10.1007/s00455-017-9832-0</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Animal model
*Aspiration
*Deglutition
*Deglutition disorders
*Dysphagia
*Infant
*Laryngeal vestibule closure
*Recurrent laryngeal nerve
2018
Animal
Animal Population Groups
Animals
Aspiration – Etiology
Aspiration/*etiology
Biological
Deglutition – Physiology
Deglutition Disorders – Etiology
Deglutition Disorders/*etiology
Deglutition/*physiology
Department of Anatomy & Neurobiology
Disease Models
Dysphagia
German Rebecca
Gould Francois
Gross Andrew
Humans
Laryngeal Nerve Injuries/*complications
Laryngeal Nerves – Injuries
Larynx
Models
NEOMED College of Medicine
Newborn
Ohlemacher Jocelyn
Oropharynx
Pneumonia
Questionnaires
Swine