Trauma history as a resilience factor for patients recovering from total knee replacement surgery.
Female; Male; Ohio; Aged; Risk Factors; Pain Measurement; Arthroplasty; Psychological Tests; Human; Descriptive Statistics; Funding Source; Scales; Middle Age; Coefficient Alpha; Effect Size; Clinical Assessment Tools; Impact of Events Scale; T-Tests; Trauma; Stress; Recovery; Replacement; Psychological; Post-Traumatic; Stress Disorders; STATISTICS; RESEARCH funding; POST-traumatic stress disorder; DESCRIPTIVE statistics; TREATMENT effectiveness; CONVALESCENCE; CORRELATION (Statistics); EFFECT sizes (Statistics); LIFE change events; LIFE skills; OHIO; PAIN measurement; PSYCHOLOGICAL tests; REHABILITATION; RESILIENCE (Personality trait); STRESS (Psychology); T-test (Statistics); TOTAL knee replacement; WOUNDS & injuries; Treatment Outcomes; Bivariate Statistics; Center for Epidemiological Studies Depression Scale; Functional Status; Hardiness; 80 and Over; Knee – Psychosocial Factors; Knee – Rehabilitation; TOTAL knee replacement – Psychological aspects
Research concerning the impact of trauma history on individuals' ability to cope with subsequent events is mixed. While many studies find that trauma history increases vulnerability for conditions such as post-traumatic stress disorder and chronic pain, others reveal that there are benefits associated with moderate levels of stress (e.g. development of coping skills). Objective: The present study investigated whether the experience of prior traumatic stressors would serve as a risk or resilience factor based on physical and emotional outcomes among patients recovering from total knee replacement surgery (TKR). Design: 110 patients undergoing unilateral, TKR completed surveys before surgery, as well as one and three months following the procedure. Results: Contrary to hypotheses, patients who reported more prior traumas experienced less severe pain and functional limitations at one- (β = −.259,p = .006) and three-month follow-up assessments (β = −.187,p = .04). A similar pattern emerged when specific types of traumas (e.g. interpersonal) were examined in relation to physical recovery. Further, patients’ trauma history was negatively related to symptoms of post-traumatic stress three-months following surgery (e.g. Avoidance:β = −.200,p = .037). Conclusion: Trauma history represents a source of resilience, rather than vulnerability, within the context of arthroplastic surgery. [ABSTRACT FROM PUBLISHER]
Cremeans-Smith Julie K; Greene Kenneth; Delahanty Douglas L
Psychology & Health
2015
2015-09
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1080/08870446.2014.1001391" target="_blank" rel="noreferrer noopener">10.1080/08870446.2014.1001391</a>
Minimal clinically important differences in the EORTC QLQ-C30 and brief pain inventory in patients undergoing re-irradiation for painful bone metastases.
*Bone metastases; *Brief pain inventory; *EORTC QLQ-C30; *Minimal Clinically Important Difference; *Minimal clinically important differences; *Radiation; 80 and over; 80 and Over; Adolescence; Adolescent; Adult; Aged; Bone Metastases – Radiotherapy; BONE metastasis; BONE metastasis – Treatment; Bone Neoplasms/*complications/radiotherapy/secondary; Brief Pain Inventory; BRIEF Pain Inventory; Cancer Patients; CANCER patients; CANCER radiotherapy; Clinical Assessment Tools; Female; Funding Source; Human; Humans; Instrument Scaling; LONGITUDINAL method; Male; Middle Age; Middle Aged; Pain Management; PAIN management; Pain/*diagnosis; Prospective Studies; Quality of Life/*psychology; Questionnaires; QUESTIONNAIRES; RANDOMIZED controlled trials; Re-Irradiation/*adverse effects; REOPERATION; Repeat Procedures; RESEARCH funding; SCALING (Social sciences); Secondary Analysis; SECONDARY analysis; Surveys and Questionnaires; Young Adult
PURPOSE: The EORTC QLQ-C30 and the Brief Pain Inventory (BPI) are validated tools for measuring quality of life (QOL) and the impact of pain in patients with advanced cancer. Interpretation of these instrument scores can be challenging and it is difficult to know what numerical changes translate to clinically significant impact in patients' lives. To address this issue, our study sought to establish the minimal clinically important differences (MCID) for these two instruments in a prospective cohort of patients with advanced cancer and painful bone metastases. METHODS: Both anchor-based and distribution-based methods were used to estimate the MCID scores from patients enrolled in a randomized phase III trial evaluating two different re-irradiation treatment schedules. For the anchor-based method, the global QOL item from the QLQ-C30 was chosen as the anchor. Spearman correlation coefficients were calculated for all items and only those items with moderate or better correlation (\textbarr\textbar \textgreater/= 0.30) with the anchor were used for subsequent analysis. A 10-point difference in the global QOL score was used to classify improvement and deterioration, and the MCID scores were calculated for each of these categories. These results were compared with scores obtained by the distribution-method, which estimates the MCID purely from the statistical characteristics of the sample population. RESULTS: A total of 375 patients were included in this study with documented pain responses and completed QOL questionnaires at 2 months. 9/14 items in the QLQ-C30 and 6/10 items in the BPI were found to have moderate or better correlation with the anchor. For deterioration, statistically significant MCID scores were found in all items of the QLQ-C30 and BPI. For improvement, statistically significant MCID scores were found in 7/9 items of the QLQ-C30 and 2/6 items of the BPI. The MCID scores for deterioration were uniformly higher than the MCIDs for improvement. Using the distribution-based method, there was good agreement between the 0.5 standard deviation (SD) values and anchor-based scores for deterioration. For improvement, there was less agreement and the anchor-based scores were lower than the 0.5 SD values obtained from the distribution-based method. CONCLUSION: We present MCID scores for the QLQ-C30 and BPI instruments obtained from a large cohort of patients with advanced cancer undergoing re-irradiation for painful bone metastases. The results from this study were compared to other similar studies which showed larger MCID scores for improvement compared to deterioration. We hypothesize that disease trajectory and patient expectations are important factors in understanding the contrasting results. The results of this study can guide clinicians and researchers in the interpretation of these instruments.
Raman Srinivas; Ding Keyue; Chow Edward; Meyer Ralph M; van der Linden Yvette M; Roos Daniel; Hartsell William F; Hoskin Peter; Wu Jackson S Y; Nabid Abdenour; Haas Rick; Wiggenraad Ruud; Babington Scott; Demas William F; Wilson Carolyn F; Wong Rebecca K S; Zhu Liting; Brundage Michael
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
2018
2018-04
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1007/s11136-017-1745-8" target="_blank" rel="noreferrer noopener">10.1007/s11136-017-1745-8</a>