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40
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Text
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URL Address
<a href="http://doi.org/10.3109/09546634.2011.643221" target="_blank" rel="noreferrer noopener">http://doi.org/10.3109/09546634.2011.643221</a>
Pages
26–34
Issue
1
Volume
23
Dublin Core
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Title
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A fixed-dose combination of adapalene 0.1%-BPO 2.5% allows an early and sustained improvement in quality of life and patient treatment satisfaction in severe acne.
Publisher
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The Journal of dermatological treatment
Date
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2012
2012-02
Subject
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Adult; Female; Humans; Male; Adolescent; Young Adult; Child; Severity of Illness Index; Quality of Life/*psychology; Double-Blind Method; *Patient Satisfaction; Drug Combinations; Acne Vulgaris/*drug therapy/*psychology; Adapalene; Benzoyl Peroxide/administration & dosage/*therapeutic use; Dermatologic Agents/administration & dosage/*therapeutic use; Naphthalenes/administration & dosage/*therapeutic use
Creator
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Brodell Robert T; Schlosser Bethanee J; Rafal Elyse; Toth Darryl; Tyring Stephen; Wertheimer Albert; Kerrouche Nabil; Bucher Delphine
Description
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INTRODUCTION: Acne has a significant negative impact on quality of life (QoL): lack of self-confidence, depressive symptoms and suicidal thoughts. The objective was to assess the impact of an initial and continued therapy in severe acne patients through patient-related outcomes (PRO). METHODS: In two sequential double-blind randomized studies, patients received either adapalene 0.1% and benzoyl peroxide 2.5% (A-BPO) or vehicle, associated with doxycycline 100 mg for 12 weeks. Patients having obtained at least a good improvement according to investigator global assessment were re-randomized for a 24-week therapy with
Identifier
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<a href="http://doi.org/10.3109/09546634.2011.643221" target="_blank" rel="noreferrer noopener">10.3109/09546634.2011.643221</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Patient Satisfaction
2012
Acne Vulgaris/*drug therapy/*psychology
Adapalene
Adolescent
Adult
Benzoyl Peroxide/administration & dosage/*therapeutic use
Brodell Robert T
Bucher Delphine
Child
Dermatologic Agents/administration & dosage/*therapeutic use
Double-Blind Method
Drug Combinations
Female
Humans
Kerrouche Nabil
Male
Naphthalenes/administration & dosage/*therapeutic use
Quality of Life/*psychology
Rafal Elyse
Schlosser Bethanee J
Severity of Illness Index
The Journal of dermatological treatment
Toth Darryl
Tyring Stephen
Wertheimer Albert
Young Adult