Browse Items · NEOMED Bibliography Database

Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.

Bile acids activate farnesoid X receptor (FXR) and G protein-coupled bile acid receptor-1 (aka Takeda G protein-coupled receptor-5 [TGR5]) to regulate bile acid metabolism and glucose and insulin sensitivity. FXR and TGR5 are coexpressed in the…

Antipsychotic effects of verapamil in schizophrenia.

The antipsychotic effects of verapamil were tested in a double-blind, placebo-controlled, randomized study in 18 patients who met Research Diagnostic Criteria for acute schizophrenia. The antipsychotic effect of verapamil as measured by the…

Tags: 1987, Adult, Clinical Trials as Topic, Double-Blind Method, Female, Haloperidol/therapeutic use, Humans, Male, Middle Aged, Price W A, Random Allocation, Schizophrenia/*drug therapy, The Hillside journal of clinical psychiatry, Verapamil/*therapeutic use

Gallstone pancreatitis: a prospective randomized trial of the timing of surgery.

The correct timing of surgery in cases of gallstone pancreatitis is debatable. To delineate more clearly the influence of the timing of surgery in the treatment of the disease, a prospective randomized clinical study of early surgery (less than 48…

Transplacental cardiotoxicity of cocaine: atrial damage following treatment in early pregnancy.

Using light, transmission (TEM) and scanning (SEM) electron microscopy, cocaine-induced defects were observed in hamster atria. Compared with controls, the treated atria from neonates show endocardial and myocardial damages as the atrial walls…

Tags: 1991, Animals, Cocaine/*toxicity, Congenital/chemically induced/*pathology, Cricetinae, Dalbec J P, Electron, Endocardium/ultrastructure, Female, Gilloteaux J, Heart Atria/*ultrastructure, Heart Defects, Maternal-Fetal Exchange, Mesocricetus, Microscopy, Pregnancy, Random Allocation, Scanning, Scanning microscopy

Bromocriptine therapy in cocaine withdrawal.

Twenty-four cocaine addicts who experienced withdrawal symptoms were studied for six weeks in a double-blind design. Half of the group received daily treatment with bromocriptine and the other half with placebo. Significant relief with bromocriptine…

Tags: *Cocaine, 1987, Adult, Baumgartel P, Bromocriptine/*therapeutic use, Clinical Trials as Topic, DiMarzio L R, Double-Blind Method, Giannini A J, Humans, Journal of clinical pharmacology, Male, Psychiatric Status Rating Scales, Random Allocation, Substance Withdrawal Syndrome/*drug therapy/psychology

Adherence to Endotracheal Tube Depth Guidelines and Incidence of Malposition in Infants and Children.

BACKGROUND: Adherence to guidelines for endotracheal tube (ETT) insertion depth may not be sufficient to prevent malposition or harm to the patient. To obtain an estimate of ETT malpositioning, we evaluated initial postintubation chest radiographs…

Tags: 2018, Bigham Michael T, Chi Square Test, Chi-Square Distribution, Child, Confidence Intervals, Data Analysis Software, Descriptive Statistics, Female, Guideline Adherence, Guideline Adherence/*statistics & numerical data, Hospitals, Human, Humans, Incidence, Infant, Inpatients, Intensive Care Units, Intratracheal – Standards – United States, Intratracheal/adverse effects/standards/*statistics & numerical data, Intubation, Male, McNinch Neil L, Medical Errors/*statistics & numerical data, NRP, Odds Ratio, Ohio, P-Value, PALS, Pediatric – Ohio, Pediatrics, Practice Guidelines, Preschool, Prough Donald S, Radiography, Radiography/*statistics & numerical data, Random Allocation, Respiratory care, Retrospective Design, ROC Curve, Thoracic, Trachea/diagnostic imaging, tracheal tube malposition, United States, Volsko Teresa A

Daily spontaneous running alters behavioral and neurochemical indexes of nigrostriatal function.

Behavioral and neurochemical indexes of nigrostriatal dopaminergic function were compared between sedentary control rats (n = 12) and daily spontaneous running (DSR) male rats (n = 10). Nine weeks of DSR did not significantly alter body, heart,…

Anatomical Look Into OnabotulinumtoxinA Injection for Chronic Migraine Headache.

BACKGROUND AND OBJECTIVES: While existing studies about onabotulinumtoxinA for chronic migraines have focused on injection location and appropriate dosing, little consideration has been given to patient body habitus and its potential impact on…

Tags: 2018, 80 and over, Adolescence, Adolescent, Adult, Aged, Anatomic Landmarks/anatomy & histology/*diagnostic imaging, Ansari Hossein, Blaha Taryn, Body Regions, Body Regions – Anatomy and Histology, Botulinum Toxins, Botulinum Toxins – Administration and Dosage, Chronic Disease, Female, Human, Humans, Male, Middle Age, Middle Aged, Migraine, Migraine – Drug Therapy, Migraine Disorders/*diagnostic imaging/*drug therapy, Narouze Samer, Neck Muscles, Neck Muscles – Anatomy and Histology, Neck Muscles – Drug Effects, Neck Muscles/anatomy & histology/*diagnostic imaging/drug effects, Pilot Projects, Pilot Studies, Random Allocation, Random Assignment, Regional anesthesia and pain medicine, Swanson Marco, Tomography, Totonchi Ali, Type A/*administration & dosage, Wu-Fienberg Yuewei, X-Ray Computed – Methods, X-Ray Computed/methods, Young Adult, Zardouz Shawn

Thermography as a diagnostic aid in sciatica.

Thermography has been proposed as a diagnostic aid in patients with sciatica. Supporters of thermography state that: (a) normal patients have normal thermograms of their lower extremities, and (b) abnormal patients (with disk ruptures causing…

Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.

Inflammation arising from central and/or peripheral sources contributes to the pathogenesis of multiple neurodegenerative diseases including Parkinson's disease (PD). Emerging data suggest that differential activation of glia could lead to the…

Conditioned place aversion produced by dopamine release inhibition.

CGS 10746B, a dopamine release inhibitor with properties similar to the atypical antipsychotic clozapine, was assessed as to its behavioral properties using spontaneous locomotor activity and the conditioned place preference test. Rats conditioned…

G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice.

Bile acids are signaling molecules that play a critical role in regulation of hepatic metabolic homeostasis by activating nuclear farnesoid X receptor (Fxr) and membrane G-protein-coupled receptor (Takeda G-protein-coupled receptor 5; Tgr5). The role…

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