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Text
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URL Address
<a href="http://doi.org/10.1016/j.jpeds.2007.03.001" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jpeds.2007.03.001</a>
Pages
187–191
Issue
2
Volume
151
Dublin Core
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Title
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Aeroallergen sensitization in healthy children: racial and socioeconomic correlates.
Publisher
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Journal of Pediatrics
Date
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2007
2007-08
Subject
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Female; Male; Socioeconomic Factors; Incidence; Child; Risk Factors; Sensitivity and Specificity; Odds Ratio; Health Status; Probability; Confidence Intervals; Human; Adolescence; Logistic Regression; Case Control Studies; Immunization; Preschool; Population; Air Pollutants – Immunology; Allergens – Immunology; Hypersensitivity – Diagnosis; Hypersensitivity – Epidemiology; Hypersensitivity – Immunology; Respiratory Hypersensitivity – Diagnosis; Respiratory Hypersensitivity – Ethnology; Respiratory Hypersensitivity – Immunology; Skin Tests – Methods
Creator
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Stevenson MD; Sellins S; Grube E; Schroer K; Gupta J; Wang N; Khurana Hershey GK; Stevenson Michelle D; Sellins Stacey; Grube Emilie; Schroer Kathy; Gupta Jayanta; Wang Ning; Khurana Hershey Gurjit K
Description
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Objective: Allergic sensitization is very prevalent and often precedes the development of allergic disease. This study examined the association of race with allergic sensitization among healthy children with no family history of atopy.Study Design: Two hundred seventy-five children, predominantly from lower socioeconomic strata, from Cincinnati, Ohio, ages 2 to 18 years without a family or personal history of allergic diseases, underwent skin prick testing to 11 allergen panels. The Pediatric Allergic Disease Quality of Life Questionnaire (PADQLQ) was used to examine the impact of sensitization on quality of life.Results: Thirty-nine percent of healthy children were sensitized to 1 or more allergen panels. Multivariate logistic regression showed increased risk among African-American children for any sensitization (OR, 2.17; [95% CI: 1.23, 3.84]) and sensitization to any outdoor allergen (OR, 2.96 [95% CI: 1.52, 5.74]). Eighty-six percent of children had PADQLQ scores of 1 or less (0 to 6 scale).Conclusions: Allergic sensitization is prevalent even among children who do not have a personal or family history of asthma, allergic rhinitis, or atopic dermatitis and who have no evidence of current, even subtle effects from this sensitization on allergic disease-related quality of life. African-American children are at greater risk for presence of sensitization, especially to outdoor allergens.
Identifier
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<a href="http://doi.org/10.1016/j.jpeds.2007.03.001" target="_blank" rel="noreferrer noopener">10.1016/j.jpeds.2007.03.001</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2007
Adolescence
Air Pollutants – Immunology
Allergens – Immunology
Case Control Studies
Child
Confidence Intervals
Female
Grube E
Grube Emilie
Gupta J
Gupta Jayanta
Health Status
Human
Hypersensitivity – Diagnosis
Hypersensitivity – Epidemiology
Hypersensitivity – Immunology
Immunization
Incidence
Journal of Pediatrics
Khurana Hershey GK
Khurana Hershey Gurjit K
Logistic Regression
Male
Odds Ratio
Population
Preschool
Probability
Respiratory Hypersensitivity – Diagnosis
Respiratory Hypersensitivity – Ethnology
Respiratory Hypersensitivity – Immunology
Risk Factors
Schroer K
Schroer Kathy
Sellins S
Sellins Stacey
Sensitivity and Specificity
Skin Tests – Methods
Socioeconomic Factors
Stevenson MD
Stevenson Michelle D
Wang N
Wang Ning