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Text
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URL Address
<a href="http://doi.org/10.1016/j.annemergmed.2005.02.002" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.annemergmed.2005.02.002</a>
Pages
592–594
Issue
6
Volume
45
Dublin Core
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Title
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Shortness of breath, syncope, and cardiac arrest caused by systemic mastocytosis.
Publisher
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Annals of emergency medicine
Date
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2005
2005-06
Subject
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Adult; Dyspnea/etiology; Epinephrine/therapeutic use; Heart Arrest/etiology; Humans; Hypotension/etiology; Male; Mastocytosis; Syncope/etiology; Systemic/complications/*diagnosis/drug therapy
Creator
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Rohr Susan M; Rich Michael W; Silver Kevin H
Description
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During a 3-month period, a 33-year-old man presented to the emergency department on 4 occasions with dyspnea, palpitations, and syncope. His initial presentation was accompanied by acute myocardial injury and ventricular fibrillation. An extensive evaluation spanned the 3 months and included echocardiography, cardiac catheterization, electrophysiology study, tilt-table evaluation, pulmonary angiography, electroencephalography, and serum and urine analysis. Diagnosis eluded clinicians until a rash was recognized to be urticaria pigmentosa, and biopsy of the rash then implicated mastocytosis. Since the initiation of pharmacotherapy nearly 5 years ago, the patient has remained asymptomatic. This case demonstrates that systemic mastocytosis can present as recurrent syncope and even as cardiac arrest. Diagnosis of this rare but potentially fatal disease is made particularly challenging by its protean manifestations.
Identifier
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<a href="http://doi.org/10.1016/j.annemergmed.2005.02.002" target="_blank" rel="noreferrer noopener">10.1016/j.annemergmed.2005.02.002</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2005
Adult
Annals of emergency medicine
Dyspnea/etiology
Epinephrine/therapeutic use
Heart Arrest/etiology
Humans
Hypotension/etiology
Male
Mastocytosis
Rich Michael W
Rohr Susan M
Silver Kevin H
Syncope/etiology
Systemic/complications/*diagnosis/drug therapy