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Text
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URL Address
<a href="http://doi.org/10.1002/ajhb.10077" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ajhb.10077</a>
Pages
532–537
Issue
4
Volume
14
Dublin Core
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Title
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Skeletal clues apparently distinguishing Waldenstrom's macroglobulinemia from multiple myeloma and leukemia.
Publisher
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American journal of human biology : the official journal of the Human Biology Council
Date
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2002
2002-08
Subject
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Bone and Bones/diagnostic imaging/*pathology; Diagnosis; Differential; Humans; Leukemia/*diagnosis/pathology; Male; Middle Aged; Multiple Myeloma/*diagnosis/pathology; Radiography; Waldenstrom Macroglobulinemia/*diagnosis/pathology
Creator
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Rothschild B M; Ruhli F; Rothschild C
Description
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This study was conducted to characterize macroscopically and by conventional radiography the bony lesions in a case of Waldenstrom's macroglobulinemia and to compare and contrast it with those of the other major hematologic lymphoproliferative disorders, multiple myeloma and leukemia. Two varieties of lytic skeletal lesions were found in Waldenstrom's macroglobulinemia. One was sharply defined, spheroid lesions with smooth borders and effaced/erased trabeculae. The second was in the form of coalescing pits (holes) with smooth, minimally remodeled edges. The appearance combined features of multiple myeloma and leukemia, but were mutually exclusive in those diseases. Spheroid lesions with effaced edges were absent in leukemia, while pits were absent in multiple myeloma. Fronts of resorption were not noted in Waldenstrom's macroglobulinemia. The combination of some of the features of leukemia and myeloma appear to allow recognition of Waldenstrom's macroglobulinemia.
Identifier
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<a href="http://doi.org/10.1002/ajhb.10077" target="_blank" rel="noreferrer noopener">10.1002/ajhb.10077</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2002
American journal of human biology : the official journal of the Human Biology Council
Bone and Bones/diagnostic imaging/*pathology
Diagnosis
Differential
Humans
Leukemia/*diagnosis/pathology
Male
Middle Aged
Multiple Myeloma/*diagnosis/pathology
Radiography
Rothschild B M
Rothschild C
Ruhli F
Waldenstrom Macroglobulinemia/*diagnosis/pathology