BRITTLE DIABETES TREATED WITH INTENSIFIED THERAPY AND A POCKET INSULIN DOSAGE COMPUTER
Creator
Sakkal S
Publisher
Diabetes Nutrition & Metabolism
Date
1993
1993-04
Description
Brittle diabetes is a therapeutic challenge. The first experience with a pocket Insulin Dosage Computer (IDC(TM)) in brittle diabetes was conducted in the form of a clinical N-of-1 trial. After intensified conventional therapy (ICT) the patients used the insulin dosage computer (ICT+IDC), and then the IDC was withdrawn (ICT-IDC). During ICT+IDC therapy, weekly pre-prandial mean blood glucose levels, glycohemoglobin levels and quality of life were all significantly improved. Hypoglycemia was eliminated. When the IDC was withdrawn (ICT-IDC), metabolic control deteriorated. The 2-tailed p value was used for statistical analysis.