1
40
16
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
107-108
Issue
2
Volume
21
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Characterization Of The Early Events In Vitamin C And K-3-induced Death Of Human Prostate Tumor Cells
Publisher
An entity responsible for making the resource available
Scanning
Date
A point or period of time associated with an event in the lifecycle of the resource
1999
1999-03
Subject
The topic of the resource
Instruments & Instrumentation; microscopy
Creator
An entity primarily responsible for making the resource
Jamison J M; Gilloteaux J J; Neal D; Summers J L
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1999
Gilloteaux J J
Instruments & Instrumentation
Jamison J M
Journal Article or Conference Abstract Publication
Microscopy
Neal D
Scanning
Summers J L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
137-149
Issue
3
Volume
25
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Autoschizis Of Human Ovarian Carcinoma Cells: Scanning Electron And Light Microscopy Of A New Cell Death Induced By Sodium Ascorbate: Menadione Treatment
Publisher
An entity responsible for making the resource available
Scanning
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003-05
Subject
The topic of the resource
adenocarcinoma; ascorbate; autoschizis; cancer-chemotherapy; combined vitamin-c; cultured-mammalian-cells; growth-invitro; induced oxidative stress; Instruments & Instrumentation; MDAH 2774; menadione; Microscopy; Microscopy; n-nitrosomorpholine; nuclear matrix; ovary; scanning; synergistic antitumor-activity; tumor-cells; ultrastructural aspects
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Jamison J M; Arnold D; Jarjoura D; Von Greuningen V; Summers J L
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2003
Adenocarcinoma
Arnold D
ascorbate
autoschizis
cancer-chemotherapy
combined vitamin-c
cultured-mammalian-cells
Gilloteaux J
growth-invitro
induced oxidative stress
Instruments & Instrumentation
Jamison J M
Jarjoura D
MDAH 2774
menadione
Microscopy
n-nitrosomorpholine
nuclear matrix
ovary
Scanning
Summers J L
synergistic antitumor-activity
tumor-cells
ultrastructural aspects
Von Greuningen V
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
564-575
Issue
8
Volume
20
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Cancer Cell Necrosis By Autoschizis: Synergism Of Antitumor Activity Of Vitamin C : Vitamin K-3 On Human Bladder Carcinoma T24 Cells
Publisher
An entity responsible for making the resource available
Scanning
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1998-11
Subject
The topic of the resource
apoptosis; bladder; cancer; combinations; cultured-mammalian-cells; cytoskeleton; death; features; induced oxidative stress; Instruments & Instrumentation; mechanism; Microscopy; necrosis; potentiation; tumor; ultrastructure; vitamins
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Jamison J M; Arnold D; Ervin E; Eckroat L; Docherty J J; Neal D; Summers J L
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1998
Apoptosis
Arnold D
Bladder
Cancer
combinations
cultured-mammalian-cells
cytoskeleton
Death
Docherty J J
Eckroat L
Ervin E
features
Gilloteaux J
induced oxidative stress
Instruments & Instrumentation
Jamison J M
mechanism
Microscopy
Neal D
Necrosis
potentiation
Scanning
Summers J L
Tumor
ultrastructure
vitamins
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
635-644
Issue
7
Volume
70
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pinch-off syndrome: Case report and collective review of the literature
Publisher
An entity responsible for making the resource available
American Surgeon
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-07
Subject
The topic of the resource
Surgery; electron-microscopy; system; hemodialysis; embolization; permanent subclavian catheters; port; rare complication; scanning; sign; spontaneous fracture; venous access devices
Creator
An entity primarily responsible for making the resource
Mirza B; Vanek V W; Kupensky D T
Description
An account of the resource
Pinch-off syndrome (POS) occurs when a long-term central venous catheter is compressed between the clavicle and the first rib. The compression can cause transient obstruction of the catheter and may result in a tear or even complete transsection and embolization of the catheter. POS may be preceded by a finding of "pinch-off sign" on chest X-ray (CXR) films in which the catheter is indented as it passes beneath the clavicle. We performed a collective review of the 109 cases of POS in the medical literature and report 3 new cases. On average, POS occurs 5.3 months after the insertion of the catheter but has ranged from immediately after insertion to 60 months later. If the subclavian vein is used for access, then an upright CXR should be obtained after the procedure and periodically thereafter to rule-out POS. Treatment of POS is removal of the catheter. If the tip of the catheter has embolized, it can usually be retrieved percutaneously with a transvenous snare. POS can be prevented by using the internal jugular vein for access rather than the subclavian vein.
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2004
American Surgeon
electron-microscopy
embolization
Hemodialysis
Journal Article or Conference Abstract Publication
Kupensky D T
Mirza B
permanent subclavian catheters
port
rare complication
Scanning
sign
spontaneous fracture
Surgery
system
Vanek V W
venous access devices
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
35–52
Issue
1
Volume
27
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Morphological aspects of female Syrian hamster gallbladder induced by one-month sex steroid treatment.
Publisher
An entity responsible for making the resource available
Journal of submicroscopic cytology and pathology
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
1995-01
Subject
The topic of the resource
Female; Animals; Body Weight; Lipids/blood; Organ Size; Cricetinae; Mesocricetus; Epithelium/drug effects/ultrastructure; Estradiol/*toxicity; Medroxyprogesterone/*toxicity; Gallbladder/*drug effects/metabolism/ultrastructure; Microscopy; Electron; Scanning
Creator
An entity primarily responsible for making the resource
Karkare S; Kelly T R; Gilloteaux J
Description
An account of the resource
Light (LM), transmission (TEM), and scanning (SEM) electron microscopy were used to characterize morphological changes induced in the gallbladder epithelium of female Syrian hamsters in response to one-month estradiol alone (E) and estradiol with medroxyprogesterone (E + MP) treatments. TEM data were correlated with the SEM observations. Compared with control (C), E- and E + MP-treated hamsters showed significant decreases in body weight, while the liver and gallbladder, and uterus weights increased. Moreover, E treatment induced some subcellular changes (microvilli, nucleus, mitochondria, RER, glycogen, abundant apical granules). The E + MP treatment appeared to exacerbate these similar changes and, in addition, induced apical excrescences and cell shedding. Both E and E + MP gallbladders showed luminal micelles, cellular debris and crystalliths associated with mucus. Simultaneously, an increased acidification of the mucoid content of the apical granules was noticed.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1995
Animals
Body Weight
Cricetinae
Electron
Epithelium/drug effects/ultrastructure
Estradiol/*toxicity
Female
Gallbladder/*drug effects/metabolism/ultrastructure
Gilloteaux J
Journal of submicroscopic cytology and pathology
Karkare S
Kelly T R
Lipids/blood
Medroxyprogesterone/*toxicity
Mesocricetus
Microscopy
Organ Size
Scanning
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
519–29; discussion 529–531
Issue
2
Volume
5
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Transplacental cardiotoxicity of cocaine: atrial damage following treatment in early pregnancy.
Publisher
An entity responsible for making the resource available
Scanning microscopy
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991-06
Subject
The topic of the resource
Female; Animals; Random Allocation; Pregnancy; Cricetinae; Mesocricetus; Cocaine/*toxicity; Microscopy; Endocardium/ultrastructure; Heart Atria/*ultrastructure; Maternal-Fetal Exchange; Electron; Scanning; Congenital/chemically induced/*pathology; Heart Defects
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Dalbec J P
Description
An account of the resource
Using light, transmission (TEM) and scanning (SEM) electron microscopy, cocaine-induced defects were observed in hamster atria. Compared with controls, the treated atria from neonates show endocardial and myocardial damages as the atrial walls thicken. SEM micrographs show intensive blebbing, damage and incomplete coverage of myocardium by the endocardial endothelium. TEM data demonstrate blebs, thinning, and other endothelial cell injuries and complement the SEM findings. Areas of endothelial sloughing may facilitate the formation of luminal and mural thrombi as noticed in many neonatal atria. Adjacent subendocardial myocardial cells display contraction bands, swellings, and vacuolizations. Local and large areas of damaged myocardial cells are observed in the subendothelial spaces; they contact fibroblasts squeezed or intercalated between the subendocardial spaces and the basal side of damaged endothelial cells. Many of these defects correspond to well-known ischemic changes. One can hypothesize that cocaine-induced defects appear to be linked to membranous alterations, including those associated with the endothelial cells of the endocardium.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1991
Animals
Cocaine/*toxicity
Congenital/chemically induced/*pathology
Cricetinae
Dalbec J P
Electron
Endocardium/ultrastructure
Female
Gilloteaux J
Heart Atria/*ultrastructure
Heart Defects
Maternal-Fetal Exchange
Mesocricetus
Microscopy
Pregnancy
Random Allocation
Scanning
Scanning microscopy
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
159–173
Issue
1
Volume
9
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Scanning electron microscopy and transmission electron microscopy aspects of synergistic antitumor activity of vitamin C - vitamin K3 combinations against human prostatic carcinoma cells.
Publisher
An entity responsible for making the resource available
Scanning microscopy
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
1995-03
Subject
The topic of the resource
Humans; Male; Antineoplastic Agents/*pharmacology; Drug Synergism; Coloring Agents; Ascorbic Acid/*pharmacology; Carcinoma/*drug therapy/pathology; Cell Membrane/drug effects/ultrastructure; Cytoskeleton/drug effects/ultrastructure; Mitochondria/drug effects/ultrastructure; Prostatic Neoplasms/*drug therapy/pathology; Tetrazolium Salts; Thiazoles; Vitamin K/*pharmacology; Microscopy; Electron; Cultured; Scanning; Tumor Cells; Drug Therapy; Combination
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Jamison J M; Venugopal M; Giammar D; Summers J L
Description
An account of the resource
A MTT/formazan assay was used to evaluate the antitumor activity of vitamin C (Vit C), vitamin K3 (Vit K3), or vitamin C:vitamin K3 combinations against a human prostatic carcinoma cell line (DU145). Both Vit C and Vit K3 alone exhibited antitumor activity, but only at elevated doses. When Vit C and Vit K3 were combined at a C:K3 ratio of 100:1 and administered to the carcinoma cells, the 50% cytotoxic concentrations (CD50) of the vitamins decreased 10- to 60-fold. Subsequently, the DU145 cells were examined with transmission and scanning electron microscopy (TEM and SEM) following a 1 hour treatment with Vit C, Vit K3, or Vit C/K3 combined at their 50% cytotoxic dose. Our morphological data suggest that vitamin treatment with individual vitamins affects the cytoskeleton, the mitochondria, and other membranous components of the cell. Treatment with the vitamin combination appears to potentiate the effects of the individual vitamin treatment. Specifically, there are abundant necrotic cells. The surviving cells display morphological defects characteristic of cell injury.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1995
Antineoplastic Agents/*pharmacology
Ascorbic Acid/*pharmacology
Carcinoma/*drug therapy/pathology
Cell Membrane/drug effects/ultrastructure
Coloring Agents
Combination
Cultured
Cytoskeleton/drug effects/ultrastructure
Drug Synergism
Drug Therapy
Electron
Giammar D
Gilloteaux J
Humans
Jamison J M
Male
Microscopy
Mitochondria/drug effects/ultrastructure
Prostatic Neoplasms/*drug therapy/pathology
Scanning
Scanning microscopy
Summers J L
Tetrazolium Salts
Thiazoles
Tumor Cells
Venugopal M
Vitamin K/*pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
519–533
Issue
4
Volume
25
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Epithelial surface changes and induction of gallstones in the male Syrian hamster gallbladder as a result of a two-month sex steroid treatment.
Publisher
An entity responsible for making the resource available
Journal of submicroscopic cytology and pathology
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-10
Subject
The topic of the resource
Male; Animals; Body Weight/drug effects; Reference Values; Cricetinae; Mesocricetus; Estradiol/*toxicity; Medroxyprogesterone/*toxicity; Cell Membrane/pathology/ultrastructure; Cholelithiasis/chemically induced/*pathology; Cytoplasmic Granules/ultrastructure; Epithelium/pathology/ultrastructure; Gallbladder/drug effects/*pathology/ultrastructure; Vacuoles/ultrastructure; Microscopy; Electron; Scanning
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Kosek E; Kelly T R
Description
An account of the resource
Transmission (TEM) and scanning (SEM) electron microscopic observations were correlated to characterize morphologic changes induced in the gallbladder of male Syrian hamsters following a two-month estradiol (E) and estradiol + medroxyprogesterone (E + MP) treatment. Compared to control (C), E-treated surface epithelial cells show pleomorphism, cytoplasmic vacuolizations, apical granules, excrescences and decapitations, and small gallstone-like deposits. Following both E + MP treatment, a large accumulation of apical granules containing acidic mucoid products, abundant intraluminal deposits and numerous fields of observation suggest that cell debris and mucous condensation could participate in the formation of the large intraluminal gallstone-like deposits detected as a result of this treatment. In control gallbladders these events were never observed. MP added to E also increases liver and gallbladder weight as well as blood lipid levels. These findings complement and confirm other previous data obtained following short steroid treatment in male, ovariectomized and intact female hamsters. In addition, these results support our hypothesis that gallstone nucleation and growth originate from multiple factors, hormonal disturbance, modulation of liver lipid metabolism, production of cell debris and mucus, can be responsible for the initial gallstone nucleation.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Animals
Body Weight/drug effects
Cell Membrane/pathology/ultrastructure
Cholelithiasis/chemically induced/*pathology
Cricetinae
Cytoplasmic Granules/ultrastructure
Electron
Epithelium/pathology/ultrastructure
Estradiol/*toxicity
Gallbladder/drug effects/*pathology/ultrastructure
Gilloteaux J
Journal of submicroscopic cytology and pathology
Kelly T R
Kosek E
Male
Medroxyprogesterone/*toxicity
Mesocricetus
Microscopy
Reference Values
Scanning
Vacuoles/ultrastructure
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
210–211
Issue
3
Volume
20
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Characterization of the early events in vitamin C and K3-induced death of human bladder tumor cells.
Publisher
An entity responsible for making the resource available
Scanning
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1998-04
Subject
The topic of the resource
Humans; Time Factors; Drug Synergism; Microscopy; Antineoplastic Combined Chemotherapy Protocols/*pharmacology; Ascorbic Acid/administration & dosage/pharmacology; Carcinoma/*drug therapy/ultrastructure; Cell Death/*drug effects; Urinary Bladder Neoplasms/*drug therapy/ultrastructure; Vitamin K 1/administration & dosage/pharmacology; Electron; Electron/methods; Cultured/drug effects; Tumor Cells; Scanning/methods
Creator
An entity primarily responsible for making the resource
Ervin E; Jamison J M; Gilloteaux J; Docherty J J; Jasso J; Summers J L
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1998
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Ascorbic Acid/administration & dosage/pharmacology
Carcinoma/*drug therapy/ultrastructure
Cell Death/*drug effects
Cultured/drug effects
Docherty J J
Drug Synergism
Electron
Electron/methods
Ervin E
Gilloteaux J
Humans
Jamison J M
Jasso J
Microscopy
Scanning
Scanning/methods
Summers J L
Time Factors
Tumor Cells
Urinary Bladder Neoplasms/*drug therapy/ultrastructure
Vitamin K 1/administration & dosage/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1089/ten.TEA.2009.0078" target="_blank" rel="noreferrer noopener">http://doi.org/10.1089/ten.TEA.2009.0078</a>
Pages
3765–3778
Issue
12
Volume
15
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Development of bone and cartilage in tissue-engineered human middle phalanx models.
Publisher
An entity responsible for making the resource available
Tissue engineering. Part A
Date
A point or period of time associated with an event in the lifecycle of the resource
2009
2009-12
Subject
The topic of the resource
*Models; Aggrecans/genetics/metabolism; Animals; Biological; Bone Development/drug effects/*physiology; Calcium Phosphates/pharmacology; Cartilage/cytology/drug effects/*growth & development; Cattle; Chondrocytes/cytology/drug effects/metabolism; Collagen Type II/genetics/metabolism; Durapatite/pharmacology; Electron; Experimental; Finger Phalanges/cytology/diagnostic imaging/drug effects/*physiology; Gene Expression Profiling; Gene Expression Regulation/drug effects; Humans; Implants; Integrin-Binding Sialoprotein; Mice; Microscopy; Paraffin Embedding; Periosteum/cytology/drug effects; Polyesters/pharmacology; Radiography; Scanning; Sialoglycoproteins/genetics/metabolism; Tissue Engineering/*methods; Tissue Scaffolds/chemistry
Creator
An entity primarily responsible for making the resource
Wada Yoshitaka; Enjo Mitsuhiro; Isogai Noritaka; Jacquet Robin; Lowder Elizabeth; Landis William J
Description
An account of the resource
Human middle phalanges were tissue-engineered with midshaft scaffolds of poly(L-lactide-epsilon-caprolactone) [P(LA-CL)], hydroxyapatite-P(LA-CL), or beta-tricalcium phosphate-P(LA-CL) and end plate scaffolds of bovine chondrocyte-seeded polyglycolic acid. Midshafts were either wrapped with bovine periosteum or left uncovered. Constructs implanted in nude mice for up to 20 weeks were examined for cartilage and bone development as well as gene expression and protein secretion, which are important in extracellular matrix (ECM) formation and mineralization. Harvested 10- and 20-week constructs without periosteum maintained end plate cartilage but no growth plate formation. They also consisted of chondrocytes secreting type II collagen and proteoglycan, and they were composed of midshaft regions devoid of bone. In all periosteum-wrapped constructs at like times, end plate scaffolds held chondrocytes elaborating type II collagen and proteoglycan and cartilage growth plates resembling normal tissue. Chondrocyte gene expression of type II collagen, aggrecan, and bone sialoprotein varied depending on midshaft composition, presence of periosteum, and length of implantation time. Periosteum produced additional cells, ECM, and mineral formation within the different midshaft scaffolds. Periosteum thus induces midshaft development and mediates chondrocyte gene expression and growth plate formation in cartilage regions of phalanges. This work is important for understanding developmental principles of tissue-engineered phalanges and by extension those of normal growth plate cartilage and bone.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1089/ten.TEA.2009.0078" target="_blank" rel="noreferrer noopener">10.1089/ten.TEA.2009.0078</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Models
2009
Aggrecans/genetics/metabolism
Animals
Biological
Bone Development/drug effects/*physiology
Calcium Phosphates/pharmacology
Cartilage/cytology/drug effects/*growth & development
Cattle
Chondrocytes/cytology/drug effects/metabolism
Collagen Type II/genetics/metabolism
Durapatite/pharmacology
Electron
Enjo Mitsuhiro
Experimental
Finger Phalanges/cytology/diagnostic imaging/drug effects/*physiology
Gene Expression Profiling
Gene Expression Regulation/drug effects
Humans
Implants
Integrin-Binding Sialoprotein
Isogai Noritaka
Jacquet Robin
Landis William J
Lowder Elizabeth
Mice
Microscopy
Paraffin Embedding
Periosteum/cytology/drug effects
Polyesters/pharmacology
Radiography
Scanning
Sialoglycoproteins/genetics/metabolism
Tissue engineering. Part A
Tissue Engineering/*methods
Tissue Scaffolds/chemistry
Wada Yoshitaka
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0040-8166(96)80072-3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0040-8166(96)80072-3</a>
Pages
687–701
Issue
6
Volume
28
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Flow cytometric and ultrastructural aspects of the synergistic antitumor activity of vitamin C-vitamin K3 combinations against human prostatic carcinoma cells.
Publisher
An entity responsible for making the resource available
Tissue & cell
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
1996-12
Subject
The topic of the resource
*Prostatic Neoplasms; Antineoplastic Combined Chemotherapy Protocols/*pharmacology; Ascorbic Acid/administration & dosage; Cultured/drug effects/metabolism/ultrastructure; DNA/biosynthesis; Drug Synergism; Electron; Flow Cytometry; Hemostatics/administration & dosage; Humans; Male; Microscopy; Scanning; Thymidine/metabolism; Tritium; Tumor Cells; Vitamin K/administration & dosage
Creator
An entity primarily responsible for making the resource
Jamison J M; Gilloteaux J; Venugopal M; Koch J A; Sowick C; Shah R; Summers J L
Description
An account of the resource
Transmission and scanning electron microscopy and flow cytometry were employed to characterize the cytotoxic effects of vitamin C (VC), vitamin K3 (VK3), or VC-VK3 combinations on a human prostate carcinoma cell line (DU145) following a 1-h vitamin treatment and a 24-h incubation in culture medium. Cells exposed to VC exhibited membranous blebs, aberrant microvillar morphology, mitochondria with swollen cristae and intramitochondrial deposits, as well as nucleoli with segregated components. VK3-treated cells displayed a damaged cytoskeleton and membranes, a cytoplasm which contained large lumen, condensed polysomes, and severely damaged mitochondria with residual bodies, and nuclei which exhibited chromatic condensation, pyknosis, and karyolysis. VC-VK3-treated cells exhibited characteristics consistent with necrosis, i.e. swollen mitochondria and swollen, achromatic nuclei with marginated chromatin and intact envelopes, while other cells displayed characteristics consistent with apoptosis, i.e. expulsion of organelle-containing blebs, margination of nuclear chromatin, and segregation of nucleolar components. Vitamin treatment also decreased DNA synthesis, induced a S/G2 block in the cell cycle, and resulted in the accumulation of fragmented DNA. These results suggested that increased oxidative stress, subsequent membrane damage, and DNA fragmentation were responsible for enhanced cytotoxicity of the vitamin combination.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0040-8166(96)80072-3" target="_blank" rel="noreferrer noopener">10.1016/s0040-8166(96)80072-3</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Prostatic Neoplasms
1996
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Ascorbic Acid/administration & dosage
Cultured/drug effects/metabolism/ultrastructure
Department of Anatomy & Neurobiology
DNA/biosynthesis
Drug Synergism
Electron
Flow Cytometry
Gilloteaux J
Hemostatics/administration & dosage
Humans
Jamison J M
Koch J A
Male
Microscopy
NEOMED College of Medicine
Scanning
Shah R
Sowick C
Summers J L
Thymidine/metabolism
Tissue & cell
Tritium
Tumor Cells
Venugopal M
Vitamin K/administration & dosage
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0003-9969(96)00056-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0003-9969(96)00056-8</a>
Pages
1053–1063
Issue
11
Volume
41
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Variation in quantitative measures of enamel prisms from different species as assessed using confocal microscopy.
Publisher
An entity responsible for making the resource available
Archives of oral biology
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
1996-11
Subject
The topic of the resource
Animals; Chiroptera/anatomy & histology; Confocal; Crystallography; Dental Enamel/*ultrastructure; Electron; Galago/anatomy & histology; Insectivora/anatomy & histology; Lemur/anatomy & histology; Lemuridae/anatomy & histology; Mammals/*anatomy & histology; Microscopy; Primates/anatomy & histology; Scanning; Species Specificity
Creator
An entity primarily responsible for making the resource
Dumont E R
Description
An account of the resource
This study presents a statistical analysis of variability in six measures of enamel prism and ameloblast size and spacing gathered using confocal microscopy, and applies the results to a consideration of appropriate sampling strategies for taxonomic analyses. Variability within individuals was examined within depth series. Individual variability was also assessed within a nested analysis of variation for prism measurements between micrographs, specimens and species. While sample depth was not often significantly associated with differences in prism and ameloblast measures, there was significant variation between micrographs taken from the same region of a tooth. The highest levels of variation were found between species, while variation between conspecific individuals was relatively small. These results demonstrate that data gathered from several micrographs are likely to be representative of a specimen, but that several micrographs of a single specimen will rarely illustrate the range of variation contained within a species. It is essential for systematic and taxonomic analyses that several micrographs be used to characterize an individual. It is also recommended that samples from several individuals be used to characterize species. While data from isolated specimens is often of great interest, taxonomic or systematic conclusions based on isolated individuals should be approached cautiously.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0003-9969(96)00056-8" target="_blank" rel="noreferrer noopener">10.1016/s0003-9969(96)00056-8</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1996
Animals
Archives of oral biology
Chiroptera/anatomy & histology
Confocal
Crystallography
Dental Enamel/*ultrastructure
Dumont E R
Electron
Galago/anatomy & histology
Insectivora/anatomy & histology
Lemur/anatomy & histology
Lemuridae/anatomy & histology
Mammals/*anatomy & histology
Microscopy
Primates/anatomy & histology
Scanning
Species Specificity
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0040-8166(92)90022-y" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0040-8166(92)90022-y</a>
Pages
869–878
Issue
6
Volume
24
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Female sex steroid induced epithelial changes in the gallbladder of the ovariectomized Syrian hamster.
Publisher
An entity responsible for making the resource available
Tissue & cell
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1905-06
Subject
The topic of the resource
Animals; Cholesterol; Cricetinae; Dietary/*administration & dosage; Electron; Epithelium/drug effects/ultrastructure; Estrogens/*adverse effects; Female; Gallbladder/*drug effects/ultrastructure; Mesocricetus; Microscopy; Ovariectomy; Ovary/*physiology; Progesterone/*adverse effects; Scanning
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Karkare S; Ko W; Kelly T R
Description
An account of the resource
Ovariectomized Syrian hamsters treated by female sex steroids during a 1-month period show gallbladder surface epithelial changes in the fundic area consistent with apical bulging and decapitations of the epithelial cells. These events were detected in the infundibulum and the fundic or body regions of estrogen- and estrogen+progesterone-treated hamsters. In control hamsters, these events were restricted to the region in the vicinity of the bile duct. Following steroid treatment, intraluminal deposits detected resembled Ca-bilirubinate deposits described in previous studies while decapitations are similar to endometrial epithelium changes associated with hormonal physiological changes or treatments. Moreover some small electron-dense deposits are comparable to those found in human cholesterol gallstones. This report indicates that, besides an alteration in bile composition, cell fragments originating from the surface epithelium of the bile duct and/or of the gallbladder mucosal epithelium could participate in gallstone nucleation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0040-8166(92)90022-y" target="_blank" rel="noreferrer noopener">10.1016/0040-8166(92)90022-y</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Animals
Cholesterol
Cricetinae
Dietary/*administration & dosage
Electron
Epithelium/drug effects/ultrastructure
Estrogens/*adverse effects
Female
Gallbladder/*drug effects/ultrastructure
Gilloteaux J
Karkare S
Kelly T R
Ko W
Mesocricetus
Microscopy
Ovariectomy
Ovary/*physiology
Progesterone/*adverse effects
Scanning
Tissue & cell
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/cne.24012" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/cne.24012</a>
Pages
3503–3517
Issue
17
Volume
524
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Persistence of intact retinal ganglion cell terminals after axonal transport loss in the DBA/2J mouse model of glaucoma.
Publisher
An entity responsible for making the resource available
The Journal of comparative neurology
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-12
Subject
The topic of the resource
*Axonal Transport/physiology; *bouton; *mitochondria; *neurodegeneration; *retinal; *RRID:IMSRJAX:000671; *RRID:IMSRJAX:007048; *RRID:SCR002716; *RRID:SCR002865; *superior colliculus; *synapse; Animal; Animals; Disease Models; Electron; Glaucoma/metabolism/*pathology; Imaging; Inbred DBA; Mice; Microscopy; Mitochondria/pathology; Neuroanatomical Tract-Tracing Techniques; Regression Analysis; Retinal Ganglion Cells/metabolism/*pathology; Scanning; Superior Colliculi/metabolism/*pathology; Synapses/metabolism/*pathology; Three-Dimensional; Visual Pathways/metabolism/pathology
Creator
An entity primarily responsible for making the resource
Smith Matthew A; Xia Christina Z; Dengler-Crish Christine M; Fening Kelly M; Inman Denise M; Schofield Brett R; Crish Samuel D
Description
An account of the resource
Axonal transport defects are an early pathology occurring within the retinofugal projection of the DBA/2J mouse model of glaucoma. Retinal ganglion cell (RGC) axons and terminals are detectable after transport is affected, yet little is known about the condition of these structures. We examined the ultrastructure of the glaucomatous superior colliculus (SC) with three-dimensional serial block-face scanning electron microscopy to determine the distribution and morphology of retinal terminals in aged mice exhibiting varying levels of axonal transport integrity. After initial axonal transport failure, retinal terminal densities did not vary compared with either transport-intact or control tissue. Although retinal terminals lacked overt signs of neurodegeneration, transport-intact areas of glaucomatous SC exhibited larger retinal terminals and associated mitochondria. This likely indicates increased oxidative capacity and may be a compensatory response to the stressors that this projection is experiencing. Areas devoid of transported tracer label showed reduced mitochondrial volumes as well as decreased active zone number and surface area, suggesting that oxidative capacity and synapse strength are reduced as disease progresses but before degeneration of the synapse. Mitochondrial volume was a strong predictor of bouton size independent of pathology. These findings indicate that RGC axons retain connectivity after losing function early in the disease process, creating an important therapeutic opportunity for protection or restoration of vision in glaucoma. J. Comp. Neurol. 524:3503-3517, 2016. (c) 2016 Wiley Periodicals, Inc.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/cne.24012" target="_blank" rel="noreferrer noopener">10.1002/cne.24012</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Axonal Transport/physiology
*bouton
*Mitochondria
*neurodegeneration
*retinal
*RRID:IMSRJAX:000671
*RRID:IMSRJAX:007048
*RRID:SCR002716
*RRID:SCR002865
*superior colliculus
*synapse
2016
Animal
Animals
Crish Samuel D
Dengler-Crish Christine M
Department of Anatomy & Neurobiology
Department of Pharmaceutical Sciences
Disease Models
Electron
Fening Kelly M
Glaucoma/metabolism/*pathology
Imaging
Inbred DBA
Inman Denise M
Mice
Microscopy
Mitochondria/pathology
NEOMED College of Medicine
NEOMED College of Pharmacy
Neuroanatomical Tract-Tracing Techniques
Regression Analysis
Retinal Ganglion Cells/metabolism/*pathology
Scanning
Schofield Brett R
Smith Matthew A
Superior Colliculi/metabolism/*pathology
Synapses/metabolism/*pathology
The Journal of comparative neurology
Three-Dimensional
Visual Pathways/metabolism/pathology
Xia Christina Z
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ar.1092360308" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ar.1092360308</a>
Pages
479–485
Issue
3
Volume
236
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Apical excrescences in the gallbladder epithelium of the female Syrian hamster in response to medroxyprogesterone.
Publisher
An entity responsible for making the resource available
The Anatomical record
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-07
Subject
The topic of the resource
Animals; Bile/metabolism; Cholelithiasis/*chemically induced/pathology; Cholesterol/metabolism; Cricetinae; Electron; Epithelium/ultrastructure; Female; Gallbladder/*drug effects/metabolism/ultrastructure; Medroxyprogesterone Acetate/*pharmacology/toxicity; Mesocricetus/*anatomy & histology; Microscopy; Mucus/metabolism; Ovariectomy; Scanning; Sex Factors
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Karkare S; Kelly T R
Description
An account of the resource
All the intact female Syrian hamsters treated with medroxyprogesterone (MP) for a one-month period, without dietary manipulation, display gallbladder surface epithelial changes, and intraluminal deposits. These changes include excrescences in various stages, bulging, and extrusion of material from the epithelial cells. The most striking scanning electron microscopic observations are the dramatic events, comparable to apocrine-like secretory events observed in another related study using oophorectomized hamsters. Since the hamster gallbladder does not possess mucous goblet cells, it appears that this phenomenon could be a response to the MP treatment, thus providing a larger amount of mucous product than usual with cellular material, in addition to the possible alteration in the quality of the bile following this treatment. As a result of MP treatment, intraluminal deposits were also confirmed by using light and transmission electron microscopy. In control hamsters these events were not observed, however, small blebs outlining surface epithelial cells are seen. The results in this report complement the previous studies using the male and oophorectomized Syrian hamster model subjected to similar experimental conditions.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ar.1092360308" target="_blank" rel="noreferrer noopener">10.1002/ar.1092360308</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Animals
Bile/metabolism
Cholelithiasis/*chemically induced/pathology
Cholesterol/metabolism
Cricetinae
Electron
Epithelium/ultrastructure
Female
Gallbladder/*drug effects/metabolism/ultrastructure
Gilloteaux J
Karkare S
Kelly T R
Medroxyprogesterone Acetate/*pharmacology/toxicity
Mesocricetus/*anatomy & histology
Microscopy
Mucus/metabolism
Ovariectomy
Scanning
Sex Factors
The Anatomical record
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/aja.1001860206" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/aja.1001860206</a>
Pages
161–172
Issue
2
Volume
186
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Endocardial surface and atrial morphological changes during development and aging.
Publisher
An entity responsible for making the resource available
The American journal of anatomy
Date
A point or period of time associated with an event in the lifecycle of the resource
1989
1989-10
Subject
The topic of the resource
*Aging; Animals; Cricetinae; Electron; Embryonic and Fetal Development; Endocardium/embryology/growth & development/*ultrastructure; Endothelium/ultrastructure; Female; Heart Atria/embryology/growth & development/*ultrastructure; Male; Mesocricetus; Microscopy; Microvilli/ultrastructure; Pregnancy; Scanning
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Linz D
Description
An account of the resource
Light, scanning, and transmission electron microscopic observations related to morphological changes of the right atrium as well as the atrial endocardium during development (15th embryonic day and 1 day old) and aging (560 days old) in the Syrian hamster were described and correlated. From the fetus to the adult, the atrial endocardium differentiates in parallel with, or in response to, the subjacent proliferating myocytes in the atrial wall and the trabeculae. Simultaneously, the atrium compartmentalizes grossly into a main chamber and an appendicular region. There is a progressive differentiation from a rudimentary, open chamber with primitive mural ridges in the fetal atria to a distinct, separate, atrial main chamber and appendage with a dense network of trabeculae in the adult. The fetal and neonatal endocardial, endothelial cells are convex with a central nuclear bulging and attenuated cytoplasmic extensions; the adult endocardium shows a squamous endothelium. Two cell surface specializations were observed in all age groups: microvilli and blebs or cytoplasmic protrusions. The general atrial morphology and surface endocardial changes were correlated with growth and the role of the endocardial endothelium as a barrier which controls metabolic exchanges, including the transport of atrial natriuretic factor, between the myocytes and the blood. This endothelial function appears to be essential in the fetal and neonatal age groups since no blood vessels are detected in these groups.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/aja.1001860206" target="_blank" rel="noreferrer noopener">10.1002/aja.1001860206</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Aging
1989
Animals
Cricetinae
Electron
Embryonic and Fetal Development
Endocardium/embryology/growth & development/*ultrastructure
Endothelium/ultrastructure
Female
Gilloteaux J
Heart Atria/embryology/growth & development/*ultrastructure
Linz D
Male
Mesocricetus
Microscopy
Microvilli/ultrastructure
Pregnancy
Scanning
The American journal of anatomy