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40
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Text
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<a href="http://doi.org/10.1038/s41581-020-0267-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/s41581-020-0267-8</a>
ISSN
1759-507X 1759-5061
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1038/s41581-020-0267-8" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1038/s41581-020-0267-8</a>
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Update Year & Number
June 2020 Update II
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
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Title
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Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy.
Publisher
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Nature reviews. Nephrology
Date
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2020
2020-04-08
Creator
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Raina Rupesh; Bedoyan Jirair K; Lichter-Konecki Uta; Jouvet Philippe; Picca Stefano; Mew Nicholas Ah; Machado Marcel C; Chakraborty Ronith; Vemuganti Meghana; Grewal Manpreet K; Bunchman Timothy; Sethi Sidharth Kumar; Krishnappa Vinod; McCulloch Mignon; Alhasan Khalid; Bagga Arvind; Basu Rajit K; Schaefer Franz; Filler Guido; Warady Bradley A
Description
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Hyperammonaemia in children can lead to grave consequences in the form of cerebral oedema, severe neurological impairment and even death. In infants and children, common causes of hyperammonaemia include urea cycle disorders or organic acidaemias. Few studies have assessed the role of extracorporeal therapies in the management of hyperammonaemia in neonates and children. Moreover, consensus guidelines are lacking for the use of non-kidney replacement therapy (NKRT) and kidney replacement therapies (KRTs, including peritoneal dialysis, continuous KRT, haemodialysis and hybrid therapy) to manage hyperammonaemia in neonates and children. Prompt treatment with KRT and/or NKRT, the choice of which depends on the ammonia concentrations and presenting symptoms of the patient, is crucial. This expert Consensus Statement presents recommendations for the management of hyperammonaemia requiring KRT in paediatric populations. Additional studies are required to strengthen these recommendations.
Identifier
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<a href="http://doi.org/10.1038/s41581-020-0267-8" target="_blank" rel="noreferrer noopener">10.1038/s41581-020-0267-8</a>
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journalArticle
2020
Alhasan Khalid
Bagga Arvind
Basu Rajit K
Bedoyan Jirair K
Bunchman Timothy
Chakraborty Ronith
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Filler Guido
Grewal Manpreet K
journalArticle
Jouvet Philippe
June 2020 Update II
Krishnappa Vinod
Lichter-Konecki Uta
Machado Marcel C
McCulloch Mignon
Mew Nicholas Ah
Nature reviews. Nephrology
NEOMED College of Medicine
Picca Stefano
Raina Rupesh
Schaefer Franz
Sethi Sidharth Kumar
Vemuganti Meghana
Warady Bradley A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00467-018-4190-1" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00467-018-4190-1</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
925-941
Issue
5
Volume
34
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Pediatric intradialytic hypotension: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup
Publisher
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Pediatric Nephrology (Berlin, Germany)
Date
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2019
2019-05
Subject
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Blood pressure monitoring; Blood volume monitoring; Children; Dialysate cooling; Intradialytic hypotension; Mannitol; Midodrine; Sodium profiling
Creator
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Raina Rupesh; Lam Stephanie; Raheja Hershita; Krishnappa Vinod; Hothi Daljit; Davenport Andrew; Chand Deepa; Kapur Gaurav; Schaefer Franz; Sethi Sidharth Kumar; McCulloch Mignon; Bagga Arvind; Bunchman Timothy; Warady Bradley A
Description
An account of the resource
Intradialytic hypotension (IDH) is a common adverse event resulting in premature interruption of hemodialysis, and consequently, inadequate fluid and solute removal. IDH occurs in response to the reduction in blood volume during ultrafiltration and subsequent poor compensatory mechanisms due to abnormal cardiac function or autonomic or baroreceptor failure. Pediatric patients are inherently at risk for IDH due to the added difficulty of determining and attaining an accurate dry weight. While frequent blood pressure monitoring, dialysate sodium profiling, ultrafiltration-guided blood volume monitoring, dialysate cooling, hemodiafiltration, and intradialytic mannitol and midodrine have been used to prevent IDH, they have not been extensively studied in pediatric population. Lack of large-scale studies on IDH in children makes it difficult to develop evidence-based management guidelines. Here, we aim to review IDH preventative strategies in the pediatric population and outlay recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup. Without strong evidence in the literature, our recommendations from the expert panel reflect expert opinion and serve as a valuable guide.
Identifier
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<a href="http://doi.org/10.1007/s00467-018-4190-1" target="_blank" rel="noreferrer noopener">10.1007/s00467-018-4190-1</a>
2019
Bagga Arvind
Blood Pressure Monitoring
Blood volume monitoring
Bunchman Timothy
Chand Deepa
Children
Davenport Andrew
Department of Internal Medicine
Dialysate cooling
Germany)
Hothi Daljit
Intradialytic hypotension
June 2019 Update
Kapur Gaurav
Krishnappa Vinod
Lam Stephanie
Mannitol
McCulloch Mignon
Midodrine
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Pediatric nephrology (Berlin
Pediatric nephrology (Berlin, Germany)
Raheja Hershita
Raina Rupesh
Schaefer Franz
Sethi Sidharth Kumar
Sodium profiling
Warady Bradley A