1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.amjcard.2009.06.042" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.amjcard.2009.06.042</a>
Pages
1251–1255
Issue
9
Volume
104
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effects of bariatric surgery on inflammatory, functional and structural markers of coronary atherosclerosis.
Publisher
An entity responsible for making the resource available
The American journal of cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2009
2009-11
Subject
The topic of the resource
*Gastric Bypass; Adult; Biological Markers – Blood; Biomarkers/blood; Blood Flow Velocity – Physiology; Blood Flow Velocity/physiology; Blood Vessels – Pathology; Body Mass Index; Brachial Artery – Ultrasonography; Brachial Artery/diagnostic imaging; C-Reactive Protein – Analysis; C-Reactive Protein/analysis; Carotid Arteries – Pathology; Carotid Arteries/pathology; Cholesterol – Blood; Cholesterol/blood; Coronary Arteriosclerosis – Blood; Coronary Arteriosclerosis – Pathology; Coronary Arteriosclerosis – Physiopathology; Coronary Artery Disease/*blood/pathology/*physiopathology; Female; Follow-Up Studies; Gastric Bypass; Human; Humans; Male; Muscle; Prospective Studies; Smooth – Pathology; Triglycerides – Blood; Triglycerides/blood; Tunica Intima/pathology; Tunica Media/pathology; Ultrasonography; Vasodilation – Physiology; Vasodilation/physiology
Creator
An entity primarily responsible for making the resource
Habib Phillip; Scrocco John David; Terek Megan; Vanek Vincent; Mikolich J Ronald
Description
An account of the resource
This study was designed to assess the effects of bariatric weight loss surgery on structural, functional, and inflammatory markers of coronary atherosclerosis. Obesity is a worldwide epidemic and an independent risk factor for coronary atherosclerosis. It remains unclear whether surgically induced weight loss reduces cardiovascular risk. This prospective study enrolled 50 consecutive subjects with morbid obesity who underwent Roux-en-Y gastric bypass surgery (GBS) after failed attempts at medical weight loss. Subjects were recruited through a comprehensive weight loss center affiliated with an academic tertiary care hospital. All subjects had body mass indexes \textgreater or =40 kg/m(2) or body mass indexes of 35 to 40 kg/m(2) with \textgreater or =2 co-morbid obesity-related conditions. Markers of coronary atherosclerosis, including brachial artery flow-mediated dilation, carotid intima-media thickness, and high-sensitivity C-reactive protein, were measured before GBS and 6, 12, and 24 months after GBS. There were statistically significant improvements in all measured markers of coronary atherosclerosis after GBS. The mean body mass index decreased from 47 to 29.5 kg/m(2) at 24 months (p \textless0.001), the mean carotid intima-media thickness regressed from 0.84 to 0.50 mm at 24 months (p \textless0.001), mean flow-mediated dilation improved from 6.0% to 14.9% at 24 months (p \textless0.05), and mean high-sensitivity C-reactive protein decreased from 1.23 to 0.65 mg/dl at 6 months (p \textless0.001) and to 0.35 mg/dl at 24 months (p \textless0.001). In conclusion, GBS results in significant improvements in inflammatory, structural, and functional markers of coronary atherosclerosis.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.amjcard.2009.06.042" target="_blank" rel="noreferrer noopener">10.1016/j.amjcard.2009.06.042</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Gastric Bypass
2009
Adult
Biological Markers – Blood
Biomarkers/blood
Blood Flow Velocity – Physiology
Blood Flow Velocity/physiology
Blood Vessels – Pathology
Body Mass Index
Brachial Artery – Ultrasonography
Brachial Artery/diagnostic imaging
C-Reactive Protein – Analysis
C-Reactive Protein/analysis
Carotid Arteries – Pathology
Carotid Arteries/pathology
Cholesterol – Blood
Cholesterol/blood
Coronary Arteriosclerosis – Blood
Coronary Arteriosclerosis – Pathology
Coronary Arteriosclerosis – Physiopathology
Coronary Artery Disease/*blood/pathology/*physiopathology
Department of Internal Medicine
Female
Follow-Up Studies
Gastric Bypass
Habib Phillip
Human
Humans
Male
Mikolich J Ronald
Muscle
NEOMED College of Medicine
Prospective Studies
Scrocco John David
Smooth – Pathology
Terek Megan
The American journal of cardiology
Triglycerides – Blood
Triglycerides/blood
Tunica Intima/pathology
Tunica Media/pathology
Ultrasonography
Vanek Vincent
Vasodilation – Physiology
Vasodilation/physiology