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Text
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URL Address
<a href="http://doi.org/10.1007/bf01271567" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/bf01271567</a>
Pages
209–222
Issue
3
Volume
95
Dublin Core
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Title
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The effect of reserpine treatment in vivo upon L-dopa and amphetamine evoked dopamine and DOPAC efflux in vitro from the corpus striatum of male rats.
Publisher
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Journal of neural transmission. General section
Date
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1994
1994
Subject
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3; 4-Dihydroxyphenylacetic Acid/*metabolism; Amphetamine/*pharmacology; Animals; Cell Compartmentation; Corpus Striatum/*drug effects/metabolism; Dopamine/*metabolism; Drug Interactions; Levodopa/*pharmacology; Male; Rats; Research Design; Reserpine/*pharmacology; Secretory Rate/drug effects; Sprague-Dawley
Creator
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Dluzen D E; Liu B
Description
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In the present experiment we tested the effects of L-DOPA and amphetamine upon dopamine and DOPAC efflux in vitro from superfused corpus striatal tissue fragments of male rats who had been pretreated with reserpine. Male rats were treated with reserpine (5 mg/kg) or its vehicle at 24 hours prior to sacrifice and superfusion of the corpus striatum. Two different modes of L-DOPA (5 microM) and amphetamine (10 microM) stimulation, a brief 10-minute and a continuous
Identifier
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<a href="http://doi.org/10.1007/bf01271567" target="_blank" rel="noreferrer noopener">10.1007/bf01271567</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
3
4-Dihydroxyphenylacetic Acid/*metabolism
Amphetamine/*pharmacology
Animals
Cell Compartmentation
Corpus Striatum/*drug effects/metabolism
Dluzen D E
Dopamine/*metabolism
Drug Interactions
Journal of neural transmission. General section
Levodopa/*pharmacology
Liu B
Male
Rats
Research Design
Reserpine/*pharmacology
Secretory Rate/drug effects
Sprague-Dawley