Browse Items (9 total)
- Tags: Sequence Analysis
Genetic Inactivation of ZCCHC6 Suppresses Interleukin‐6 Expression and Reduces the Severity of Experimental Osteoarthritis in Mice.
Tags: 2019, Ahmad Nashrah, ANIMAL experimentation, Ansari Mohammad Y, Arthritis & Rheumatology, Cartilage, CARTILAGE cells, Dactinomycin, Department of Anatomy & Neurobiology, DNA-Binding Proteins, Gene Expression, GENETIC aspects, Green Jonathan, Haqqi Tariq M, In Vivo Studies, Interleukins, June 2019 Update, Khan Nazir M, Mice, MicroRNA, NEOMED College of Medicine, Novak Kimberly, Osteoarthritis, Prevention, Sequence Analysis, Severity of Illness Index, SYNOVITIS, Transcription Factors
Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha).
Tags: *DNA-Binding Proteins, 2003, Base Sequence, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Bile Acids and Salts/*pharmacology, Binding Sites/genetics, Cell Line, Chen Wenling, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Cholestanetriol 26-Monooxygenase, Cloning, Cultured, Cytoplasmic and Nuclear/genetics/metabolism, Department of Integrative Medical Sciences, DNA, DNA/chemistry/genetics, Dose-Response Relationship, Drug, gene, Gene Expression Regulation/drug effects, Genetic/*genetics, Hepatocyte Nuclear Factor 4, Humans, Luciferases/genetics/metabolism, Molecular, Molecular Sequence Data, Mutagenesis, Mutation, NEOMED College of Medicine, Phosphoproteins/genetics/*metabolism, Promoter Regions, Receptors, Recombinant Fusion Proteins/genetics/metabolism, Response Elements/genetics, Sequence Analysis, Site-Directed, Steroid Hydroxylases/*genetics, Transcription Factors/genetics/*metabolism, Transfection, Tumor Cells
Intrastrain variants of herpes simplex virus type 1 isolated from a neonate with fatal disseminated infection differ in the ICP34.5 gene, glycoprotein processing, and neuroinvasiveness.
Tags: *Genetic Variation, *Protein Processing, 1999, Amino Acid, Amino Acid Sequence, Animal, Animals, Base Sequence, Bower J R, Deoxyribonuclease BamHI, Deoxyribonuclease EcoRI, Detwiler M, Disease Models, DNA, Durishin C, Genes, Glycoproteins/metabolism, Herpesvirus 1, Human/*genetics/growth & development/isolation & purification, Humans, Inbred BALB C, Journal of virology, Karban T L, Male, Mao H, Mice, Molecular Sequence Data, Nucleic Acid, Polymerase Chain Reaction/methods, Polymorphism, Post-Translational, Rempinski D, Restriction Fragment Length, Rosenthal K S, Rozenbom E, Sequence Analysis, Sequence Homology, Viral, Viral Envelope Proteins/analysis, Viral Proteins/*genetics
Tags: *Paleopathology/instrumentation/methods, *Rheumatology, 2002, Animals, Arthritis, Body Temperature, Bone and Bones/chemistry/diagnostic imaging/immunology, Bone Diseases/*pathology, Bone Remodeling, Collagen/immunology/isolation & purification, Dinosaurs, DNA, DNA/genetics/isolation & purification, Fossils, Gout/pathology, Humans, Imaging, Immunohistochemistry, Infectious/pathology, Joint Diseases/*pathology, Mammals, Microscopy/methods, Osteoarthritis/pathology, Phylogeny, Radiography, Reactive/pathology, Reumatismo, Rheumatic Diseases/pathology, Rothschild B, Sequence Analysis, Three-Dimensional
Congenital anomaly of the inferior vena cava and factor V Leiden mutation predisposing to deep vein thrombosis.
Tags: *Mutation, 2014, Activated Protein C Resistance/*complications/diagnosis/drug therapy/genetics, Anticoagulants – Therapeutic Use, Anticoagulants/therapeutic use, Blood Coagulation Factors, deep vein thrombosis (DVT), Disease Susceptibility, DNA Mutational Analysis, Erickson Cameron R, Factor V/*genetics, Genetic Predisposition to Disease, Hematologic Diseases, Hematologic Diseases – Complications, Hematologic Diseases – Diagnosis, Hematologic Diseases – Drug Therapy, Human, Humans, Inferior – Abnormalities, Inferior – Radiography, Inferior – Ultrasonography, inferior vena cava (IVC), Inferior/*abnormalities/diagnostic imaging, Kulthia Arun, Lamparello Brooke M, lower extremities, Male, Mutation, Phlebography – Methods, Phlebography/methods, Predictive Value of Tests, Risk Factors, Sequence Analysis, Thet Zeyar, thrombophilic, Tomography, Ultrasonography, Vascular Health and Risk Management, Vascular Malformations – Complications, Vascular Malformations – Diagnosis, Vascular Malformations/*complications/diagnosis, Vena Cava, venography, Venous Thrombosis, Venous Thrombosis – Diagnosis, Venous Thrombosis – Drug Therapy, Venous Thrombosis – Etiology, Venous Thrombosis/diagnosis/drug therapy/*etiology/genetics, Virparia Vasudev, X-Ray Computed, Young Adult
Tags: 2018, Animals, Bosco Dale B, Department of Pharmaceutical Sciences, Eyo Ukpong B, Feng Lijie, Gene Expression Profiling, Gene Ontology, Hippocampus/*pathology, Huang Jun, Immunity, Interferon-beta/metabolism, Kainic Acid, Mice, Microglia/*metabolism/*pathology, Molecular brain, NEOMED College of Pharmacy, Peng Jiyun, Richardson Jason R, RNA/*methods, Seizures/*chemically induced, Sequence Analysis, Signal Transduction/genetics, Tang Ke, Up-Regulation/genetics, Wang Hui, Wu Gongxiong, Wu Long-Jun, Xu Zhiyan, Yan Cheng, Zheng Jiaying
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Tags: 1994, Acyclovir/pharmacology, Amino Acid Sequence, Antiviral Agents/metabolism/*pharmacology, Base Sequence, Binding Sites, Bromodeoxyuridine/*analogs & derivatives/metabolism/pharmacology, Deoxyuridine/analogs & derivatives/pharmacology, DNA, Docherty J J, Drug Resistance, Herpesvirus 1, Human/drug effects/*enzymology/genetics, Humans, Kinetics, Microbial, Molecular Sequence Data, Phosphonoacetic Acid/pharmacology, Phosphorylation, Point Mutation/genetics, Sequence Analysis, The Journal of general virology, Thymidine Kinase/genetics/metabolism, Thymidine/metabolism, Vidarabine/pharmacology, Wilber B A
Promoter activity and regulation of the CYP4F2 leukotriene B(4) omega-hydroxylase gene by peroxisomal proliferators and retinoic acid in HepG2 cells.
Tags: *Gene Expression Regulation, *Promoter Regions, 2000, Amino Acid Sequence, Archives of biochemistry and biophysics, Base Sequence, Cell Line, Chen L, Cloning, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System/*genetics/metabolism, Cytochrome P450 Family 4, Cytoplasmic and Nuclear/metabolism, Department of Integrative Medical Sciences, DNA, DNA Footprinting, Enzymologic, Exons, Genes, Genetic, Genetic/drug effects, Hardwick J P, Humans, Introns, Leukotriene B4/metabolism, Mixed Function Oxygenases/metabolism, Models, Molecular, Molecular Sequence Data, NEOMED College of Medicine, Peroxisome Proliferators/*metabolism, Receptors, Reporter, Retinoic Acid Receptor alpha, Retinoic Acid/metabolism, Sequence Analysis, Transcription, Transcription Factors/metabolism, Transfection, Tretinoin/*metabolism, Zhang X