1
40
8
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/2054358118792229" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/2054358118792229</a>
Pages
2054358118792229–2054358118792229
Volume
5
Dublin Core
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Title
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Antibiotic Dosing in Sustained Low-Efficiency Dialysis in Critically Ill Patients.
Publisher
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Canadian journal of kidney health and disease
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
1905-07
Subject
The topic of the resource
antibiotics; extended daily dialysis; pharmacokinetics; SLED; sustained low-efficiency dialysis
Creator
An entity primarily responsible for making the resource
Sethi Sidharth Kumar; Krishnappa Vinod; Nangethu Nisha; Nemer Paul; Frazee Lawrence A; Raina Rupesh
Description
An account of the resource
Purpose of review: Sustained low-efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. There is, therefore, a greater need for the understanding of the antibiotic dosage and pharmacokinetics in these patients, to provide them with optimal therapy. Sources of information: PubMed/Medline, Embase, and Google Scholar. Methods: PubMed/Medline, Embase, and Google Scholar databases were searched using a combination of key words: dialysis, end stage renal disease, renal failure, sustained low efficiency dialysis, extended daily dialysis, prolonged intermittent renal replacement therapy (PIRRT), and antibiotic dosing. Studies that investigated antibiotic dosing and pharmacokinetics during SLED/extended daily dialysis/PIRRT were selected for this review. Key findings: Eleven studies met inclusion criteria and selected for data extraction. The data with regard to dialysis specifications, type of antibiotic including dosages, drug clearances, and dosage recommendations are summarized in Table 1. It is a challenge to find therapeutic doses for antibiotics during SLED therapy because, in general, only aminoglycosides and vancomycin can be assayed in clinical laboratories. Limitations: Although current studies on antibiotic dosing in SLED are limited due to diverse and undersized patient populations, antibiotic dosage adjustments for patients receiving SLED discussed here will serve as a valuable guide. Future large-scale research should focus on establishing guidelines for antibiotic dosage in SLED. Implications: Pharmacokinetic principles should be taken into consideration for the appropriate dosing of drugs during SLED, yet it is vital to monitor response to drug to make sure therapeutic goals are achieved. Antibiotic dosing and timing relative to the initiation of SLED may be important to maximize either the time above the minimum inhibitory concentration (MIC) (time-dependent) or the peak to MIC ratio (concentration-dependent), balancing efficacy and toxicity concerns. Critical care physicians should liaise with nephrologists to make decisions regarding appropriate antibiotic dosing in patients undergoing SLED.
Identifier
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<a href="http://doi.org/10.1177/2054358118792229" target="_blank" rel="noreferrer noopener">10.1177/2054358118792229</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Antibiotics
Canadian journal of kidney health and disease
Department of Internal Medicine
extended daily dialysis
Frazee Lawrence A
Krishnappa Vinod
Nangethu Nisha
Nemer Paul
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
pharmacokinetics
Raina Rupesh
Sethi Sidharth Kumar
SLED
sustained low-efficiency dialysis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1038/s41581-020-0267-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/s41581-020-0267-8</a>
ISSN
1759-507X 1759-5061
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1038/s41581-020-0267-8" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1038/s41581-020-0267-8</a>
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Update Year & Number
June 2020 Update II
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
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Title
A name given to the resource
Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy.
Publisher
An entity responsible for making the resource available
Nature reviews. Nephrology
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-04-08
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Bedoyan Jirair K; Lichter-Konecki Uta; Jouvet Philippe; Picca Stefano; Mew Nicholas Ah; Machado Marcel C; Chakraborty Ronith; Vemuganti Meghana; Grewal Manpreet K; Bunchman Timothy; Sethi Sidharth Kumar; Krishnappa Vinod; McCulloch Mignon; Alhasan Khalid; Bagga Arvind; Basu Rajit K; Schaefer Franz; Filler Guido; Warady Bradley A
Description
An account of the resource
Hyperammonaemia in children can lead to grave consequences in the form of cerebral oedema, severe neurological impairment and even death. In infants and children, common causes of hyperammonaemia include urea cycle disorders or organic acidaemias. Few studies have assessed the role of extracorporeal therapies in the management of hyperammonaemia in neonates and children. Moreover, consensus guidelines are lacking for the use of non-kidney replacement therapy (NKRT) and kidney replacement therapies (KRTs, including peritoneal dialysis, continuous KRT, haemodialysis and hybrid therapy) to manage hyperammonaemia in neonates and children. Prompt treatment with KRT and/or NKRT, the choice of which depends on the ammonia concentrations and presenting symptoms of the patient, is crucial. This expert Consensus Statement presents recommendations for the management of hyperammonaemia requiring KRT in paediatric populations. Additional studies are required to strengthen these recommendations.
Identifier
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<a href="http://doi.org/10.1038/s41581-020-0267-8" target="_blank" rel="noreferrer noopener">10.1038/s41581-020-0267-8</a>
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journalArticle
2020
Alhasan Khalid
Bagga Arvind
Basu Rajit K
Bedoyan Jirair K
Bunchman Timothy
Chakraborty Ronith
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Filler Guido
Grewal Manpreet K
journalArticle
Jouvet Philippe
June 2020 Update II
Krishnappa Vinod
Lichter-Konecki Uta
Machado Marcel C
McCulloch Mignon
Mew Nicholas Ah
Nature reviews. Nephrology
NEOMED College of Medicine
Picca Stefano
Raina Rupesh
Schaefer Franz
Sethi Sidharth Kumar
Vemuganti Meghana
Warady Bradley A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.urology.2017.07.040" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.urology.2017.07.040</a>
Pages
184–191
Volume
110
Dublin Core
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Title
A name given to the resource
Cystic Diseases of Childhood: A Review.
Publisher
An entity responsible for making the resource available
Urology
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-12
Subject
The topic of the resource
*Kidney Diseases; Child; Cystic – Diagnosis; Cystic – Therapy; Cystic/diagnosis/therapy; Humans; Kidney
Creator
An entity primarily responsible for making the resource
Kwatra Shivani; Krishnappa Vinod; Mhanna Christiane; Murray Taryn; Novak Robert; Sethi Sidharth Kumar; Kumar Deepak; Raina Rupesh
Description
An account of the resource
Renal cystic lesions are considered the most common abnormality associated with the kidneys. Most renal cysts are usually uncomplicated simple cysts that are not life-threatening; however, fatal renal cystic diseases can develop from these space-occupying lesions. Although renal cystic diseases are similar in presentation, they possess distinct features, variable prognoses, and complications later in life. Early identification and effective management of these respected diseases has led to longer survival rates and better quality of life. The purpose of this review is to provide a comprehensive analysis of the most prevalent cystic diseases of the pediatric population in hopes to aid in early distinction and appropriate treatment.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.urology.2017.07.040" target="_blank" rel="noreferrer noopener">10.1016/j.urology.2017.07.040</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Kidney Diseases
2017
Child
Cystic – Diagnosis
Cystic – Therapy
Cystic/diagnosis/therapy
Department of Internal Medicine
Humans
Kidney
Krishnappa Vinod
Kumar Deepak
Kwatra Shivani
Mhanna Christiane
Murray Taryn
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Novak Robert
Raina Rupesh
Sethi Sidharth Kumar
Urology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3389/fped.2018.00306" target="_blank" rel="noreferrer noopener">http://doi.org/10.3389/fped.2018.00306</a>
Pages
306–306
Volume
6
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Fluid Overload in Critically Ill Children.
Publisher
An entity responsible for making the resource available
Frontiers in pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
1905-07
Subject
The topic of the resource
acute kidney injury; critical care; fluid overload; intensive care; pediatric nephrology
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Sethi Sidharth Kumar; Wadhwani Nikita; Vemuganti Meghana; Krishnappa Vinod; Bansal Shyam B
Description
An account of the resource
Background: A common practice in the management of critically ill patients is fluid resuscitation. An excessive administration of fluids can lead to an imbalance in fluid homeostasis and cause fluid overload (FO). In pediatric critical care patients, FO can lead to a multitude of adverse effects and increased risk of morbidity. Objectives: To review the literature highlighting impact of FO on a multitude of outcomes in critically-ill children, causative vs. associative relationship of FO with critical illness and current pediatric fluid management guidelines. Data Sources: A literature search was conducted using PubMed/Medline and Embase databases from the earliest available date until June 2017. Data Extraction: Two authors independently reviewed the titles and abstracts of all articles which were assessed for inclusion. The manuscripts of studies deemed relevant to the objectives of this review were then retrieved and associated reference lists hand-searched. Data Synthesis: Articles were segregated into various categories namely pathophysiology and sequelae of fluid overload, assessment techniques, epidemiology and fluid management. Each author reviewed the selected articles in categories assigned to them. All authors participated in the final review process. Conclusions: Recent evidence has purported a relationship between mortality and FO, which can be validated by prospective RCTs (randomized controlled trials). The current literature demonstrates that "clinically significant" degree of FO could be below 10%. The lack of a standardized method to assess FB (fluid balance) and a universal definition of FO are issues that need to be addressed. To date, the impact of early goal directed therapy and utility of hemodynamic parameters in predicting fluid responsiveness remains underexplored in pediatric resuscitation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3389/fped.2018.00306" target="_blank" rel="noreferrer noopener">10.3389/fped.2018.00306</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Acute kidney injury
Bansal Shyam B
Critical Care
Department of Internal Medicine
fluid overload
Frontiers in pediatrics
intensive care
Krishnappa Vinod
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
pediatric nephrology
Raina Rupesh
Sethi Sidharth Kumar
Vemuganti Meghana
Wadhwani Nikita
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1371/journal.pone.0195536" target="_blank" rel="noreferrer noopener">http://doi.org/10.1371/journal.pone.0195536</a>
Pages
e0195536–e0195536
Issue
4
Volume
13
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Heparin free dialysis in critically sick children using sustained low efficiency dialysis (SLEDD-f): A new hybrid therapy for dialysis in developing world.
Publisher
An entity responsible for making the resource available
PloS one
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
1905-07
Subject
The topic of the resource
Humans; Adolescent; Retrospective Studies; Child; Infant; *Critical Care/methods; Acute Kidney Injury/blood/mortality/*therapy; Critical Illness/*therapy; Developing Countries; Feasibility Studies; Follow-Up Studies; Length of Stay; Renal Dialysis/adverse effects/instrumentation/*methods; Treatment Outcome; Preschool
Creator
An entity primarily responsible for making the resource
Sethi Sidharth Kumar; Bansal Shyam B; Khare Anshika; Dhaliwal Maninder; Raghunathan Veena; Wadhwani Nikita; Nandwani Ashish; Yadav Dinesh Kumar; Mahapatra Amit Kumar; Raina Rupesh
Description
An account of the resource
BACKGROUND: In critically sick adults, sustained low efficiency dialysis [SLED] appears to be better tolerated hemodynamically and outcomes seem to be comparable to CRRT. However, there is paucity of data in critically sick children. In children, two recent studies from Taiwan (n = 11) and India (n = 68) showed benefits of SLED in critically sick children. AIMS AND OBJECTIVES: The objective of the study was to look at the feasibility and tolerability of sustained low efficiency daily dialysis-filtration [SLEDD-f] in critically sick pediatric patients. MATERIAL AND METHODS: Design: Retrospective study Inclusion criteria: All pediatric patients who had undergone heparin free SLEDD-f from January 2012 to October 2017. Measurements: Data collected included demographic details, vital signs, PRISM III at admission, ventilator parameters (where applicable), number of inotropes, blood gas and electrolytes before, during, and on conclusion of SLED therapy. Technical information was gathered regarding SLEDD-f prescription and complications. RESULTS: Between 2012-2017, a total of 242 sessions of SLEDD-f were performed on 70 patients, out of which 40 children survived. The median age of patients in years was 12 (range 0.8-17 years), and the median weight was 39 kg (range 8.5-66 kg). The mean PRISM score at admission was 8.77+/-7.22. SLEDD-f sessions were well tolerated, with marked improvement in fluid status and acidosis. Premature terminations had to be done in 23 (9.5%) of the sessions. There were 21 sessions (8.6%) terminated due to hypotension and 2 sessions (0.8%) terminated due to circuit clotting. Post- SLEDD-f hypocalcemia occurred in 15 sessions (6.2%), post- SLEDD-f hypophosphatemia occurred in 1 session (0.4%), and post- SLEDD-f hypokalemia occurred in 17 sessions (7.0%). CONCLUSIONS: This study is the largest compiled data on pediatric SLEDD-f use in critically ill patients. Our study confirms the feasibility of heparin free SLEDD-f in a larger pediatric population, and even in children weighing \textless20 kg on inotropic support.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1371/journal.pone.0195536" target="_blank" rel="noreferrer noopener">10.1371/journal.pone.0195536</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Critical Care/methods
2018
Acute Kidney Injury/blood/mortality/*therapy
Adolescent
Bansal Shyam B
Child
Critical Illness/*therapy
Department of Internal Medicine
Developing Countries
Dhaliwal Maninder
Feasibility Studies
Follow-Up Studies
Humans
Infant
Khare Anshika
Length of Stay
Mahapatra Amit Kumar
Nandwani Ashish
NEOMED College of Medicine
PloS one
Preschool
Raghunathan Veena
Raina Rupesh
Renal Dialysis/adverse effects/instrumentation/*methods
Retrospective Studies
Sethi Sidharth Kumar
Treatment Outcome
Wadhwani Nikita
Yadav Dinesh Kumar
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00467-018-4190-1" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00467-018-4190-1</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
925-941
Issue
5
Volume
34
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pediatric intradialytic hypotension: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup
Publisher
An entity responsible for making the resource available
Pediatric Nephrology (Berlin, Germany)
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-05
Subject
The topic of the resource
Blood pressure monitoring; Blood volume monitoring; Children; Dialysate cooling; Intradialytic hypotension; Mannitol; Midodrine; Sodium profiling
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Lam Stephanie; Raheja Hershita; Krishnappa Vinod; Hothi Daljit; Davenport Andrew; Chand Deepa; Kapur Gaurav; Schaefer Franz; Sethi Sidharth Kumar; McCulloch Mignon; Bagga Arvind; Bunchman Timothy; Warady Bradley A
Description
An account of the resource
Intradialytic hypotension (IDH) is a common adverse event resulting in premature interruption of hemodialysis, and consequently, inadequate fluid and solute removal. IDH occurs in response to the reduction in blood volume during ultrafiltration and subsequent poor compensatory mechanisms due to abnormal cardiac function or autonomic or baroreceptor failure. Pediatric patients are inherently at risk for IDH due to the added difficulty of determining and attaining an accurate dry weight. While frequent blood pressure monitoring, dialysate sodium profiling, ultrafiltration-guided blood volume monitoring, dialysate cooling, hemodiafiltration, and intradialytic mannitol and midodrine have been used to prevent IDH, they have not been extensively studied in pediatric population. Lack of large-scale studies on IDH in children makes it difficult to develop evidence-based management guidelines. Here, we aim to review IDH preventative strategies in the pediatric population and outlay recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup. Without strong evidence in the literature, our recommendations from the expert panel reflect expert opinion and serve as a valuable guide.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00467-018-4190-1" target="_blank" rel="noreferrer noopener">10.1007/s00467-018-4190-1</a>
2019
Bagga Arvind
Blood Pressure Monitoring
Blood volume monitoring
Bunchman Timothy
Chand Deepa
Children
Davenport Andrew
Department of Internal Medicine
Dialysate cooling
Germany)
Hothi Daljit
Intradialytic hypotension
June 2019 Update
Kapur Gaurav
Krishnappa Vinod
Lam Stephanie
Mannitol
McCulloch Mignon
Midodrine
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Pediatric nephrology (Berlin
Pediatric nephrology (Berlin, Germany)
Raheja Hershita
Raina Rupesh
Schaefer Franz
Sethi Sidharth Kumar
Sodium profiling
Warady Bradley A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s12098-019-03150-9" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s12098-019-03150-9</a>
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<a href="http://ezproxy.neomed.idm.oclc.org/login?url=http://doi.org/10.1007/s12098-019-03150-9" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1007/s12098-019-03150-9</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
March 2020 Update
NEOMED College
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Renal Replacement Therapy in Pediatric Acute Kidney Injury.
Publisher
An entity responsible for making the resource available
Indian journal of pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-01
Subject
The topic of the resource
Acute kidney injury; Dialysis; Pediatric; Renal replacement therapy
Creator
An entity primarily responsible for making the resource
Sethi Sidharth Kumar; Chakraborty Ronith; Joshi Hirva; Raina Rupesh
Description
An account of the resource
Acute kidney injury (AKI) is common in critically ill children and affects nearly
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s12098-019-03150-9" target="_blank" rel="noreferrer noopener">10.1007/s12098-019-03150-9</a>
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Format
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Journal Article
2020
Acute kidney injury
Chakraborty Ronith
Dialysis
Indian journal of pediatrics
Joshi Hirva
NEOMED College of Medicine Student
NEOMED Student Publications
Pediatric
Raina Rupesh
renal replacement therapy
Sethi Sidharth Kumar
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1371/journal.pone.0178233" target="_blank" rel="noreferrer noopener">http://doi.org/10.1371/journal.pone.0178233</a>
Pages
e0178233–e0178233
Issue
5
Volume
12
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of AKI in developing and developed countries: An international survey of pediatric dialysis modalities.
Publisher
An entity responsible for making the resource available
PloS one
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017
Subject
The topic of the resource
Humans; Child; Surveys and Questionnaires; *Developed Countries; *Developing Countries; Acute Kidney Injury/*therapy; Renal Dialysis/*methods
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Chauvin Abigail M; Bunchman Timothy; Askenazi David; Deep Akash; Ensley Michael J; Krishnappa Vinod; Sethi Sidharth Kumar
Description
An account of the resource
HYPOTHESIS: Acute kidney injury (AKI) is a common cause of morbidity and mortality worldwide, with a pediatric incidence ranging from 19.3% to 24.1%. Treatment of pediatric AKI is a source of debate in varying geographical regions. Currently CRRT is the treatment for pediatric AKI, but limitations due to cost and accessibility force use of adult equipment and other therapeutic options such as peritoneal dialysis (PD) and hemodialysis (HD). It was hypothesized that more cost-effective measures would likely be used in developing countries due to lesser resource availability. METHODS: A 26-question internet-based survey was distributed to 650 pediatric Nephrologists. There was a response rate of 34.3% (223 responses). The survey was distributed via pedneph and pcrrt email servers, inquiring about demographics, technology, resources, pediatric-specific supplies, and preference in renal replacement therapy (RRT) in pediatric AKI. The main method of analysis was to compare responses about treatments between nephrologists in developed countries and nephrologists in developing countries using difference-of-proportions tests. RESULTS: PD was available in all centers surveyed, while HD was available in 85.1% and 54.1% (p = 0.00), CRRT was available in 60% and 33.3% (p = 0.001), and SLED was available in 20% and 25% (p = 0.45) centers of developed and developing world respectively. In developing countries, 68.5% (p = 0.000) of physicians preferred PD to costlier therapies, while in developed countries it was found that physicians favored HD (72%, p = 0.00) or CRRT (24%, p = 0.041) in infants. CONCLUSIONS: Lack of availability of resources, trained physicians and funds often preclude standards of care in developing countries, and there is much development needed in terms of meeting higher global standards for treating pediatric AKI patients. PD remains the main modality of choice for treatment of AKI in infants in developing world.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1371/journal.pone.0178233" target="_blank" rel="noreferrer noopener">10.1371/journal.pone.0178233</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Developed Countries
*Developing Countries
2017
Acute Kidney Injury/*therapy
Askenazi David
Bunchman Timothy
Chauvin Abigail M
Child
Deep Akash
Department of Internal Medicine
Ensley Michael J
Humans
Krishnappa Vinod
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
PloS one
Raina Rupesh
Renal Dialysis/*methods
Sethi Sidharth Kumar
Surveys and Questionnaires