1 40 2 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1002/jmri.26555" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jmri.26555</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 1694-1703 Issue 6 Volume 49 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Intra- and interreader reproducibility of PI-RADSv2: A multireader study Publisher An entity responsible for making the resource available Journal of magnetic resonance imaging: JMRI Date A point or period of time associated with an event in the lifecycle of the resource 2019 2019-06 Subject The topic of the resource MRI; PI-RADS; prostate cancer; reader reproducibility Creator An entity primarily responsible for making the resource Smith Clayton P; Harmon Stephanie A; Barrett Tristan; Bittencourt Leonardo K; Law Yan Mee; Shebel Haytham; An Julie Y; Czarniecki Marcin; Mehralivand Sherif; Coskun Mehmet; Wood Bradford J; Pinto Peter A; Shih Joanna H; Choyke Peter L; Turkbey Baris Description An account of the resource BACKGROUND: The Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) has been in use since 2015; while interreader reproducibility has been studied, there has been a paucity of studies investigating the intrareader reproducibility of PI-RADSv2. PURPOSE: To evaluate both intra- and interreader reproducibility of PI-RADSv2 in the assessment of intraprostatic lesions using multiparametric magnetic resonance imaging (mpMRI). STUDY TYPE: Retrospective. POPULATION/SUBJECTS: In all, 102 consecutive biopsy-naïve patients who underwent prostate MRI and subsequent MR/transrectal ultrasonography (MR/TRUS)-guided biopsy. FIELD STRENGTH/SEQUENCES: Prostate mpMRI at 3T using endorectal with phased array surface coils (TW MRI, DW MRI with ADC maps and b2000 DW MRI, DCE MRI). ASSESSMENT: Previously detected and biopsied lesions were scored by four readers from four different institutions using PI-RADSv2. Readers scored lesions during two readout rounds with a 4-week washout period. STATISTICAL TESTS: Kappa (κ) statistics and specific agreement (Po ) were calculated to quantify intra- and interreader reproducibility of PI-RADSv2 scoring. Lesion measurement agreement was calculated using the intraclass correlation coefficient (ICC). RESULTS: Overall intrareader reproducibility was moderate to substantial (κ = 0.43-0.67, Po = 0.60-0.77), while overall interreader reproducibility was poor to moderate (κ = 0.24, Po = 46). Readers with more experience showed greater interreader reproducibility than readers with intermediate experience in the whole prostate (P = 0.026) and peripheral zone (P = 0.002). Sequence-specific interreader agreement for all readers was similar to the overall PI-RADSv2 score, with κ = 0.24, 0.24, and 0.23 and Po = 0.47, 0.44, and 0.54 in T2 -weighted, diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE), respectively. Overall intrareader and interreader ICC for lesion measurement was 0.82 and 0.71, respectively. DATA CONCLUSION: PI-RADSv2 provides moderate intrareader reproducibility, poor interreader reproducibility, and moderate interreader lesion measurement reproducibility. These findings suggest a need for more standardized reader training in prostate MRI. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 2. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/jmri.26555" target="_blank" rel="noreferrer noopener">10.1002/jmri.26555</a> 2019 An Julie Y Barrett Tristan Bittencourt Leonardo K Choyke Peter L Coskun Mehmet Czarniecki Marcin Harmon Stephanie A Journal of magnetic resonance imaging: JMRI June 2019 Update Law Yan Mee Mehralivand Sherif MRI NEOMED College of Medicine NEOMED College of Medicine Student NEOMED Student Publications PI-RADS Pinto Peter A Prostate cancer reader reproducibility Shebel Haytham Shih Joanna H Smith Clayton P Turkbey Baris Wood Bradford J Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1002/jmri.26555" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jmri.26555</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Intra- and interreader reproducibility of PI-RADSv2: A multireader study. Publisher An entity responsible for making the resource available Journal of magnetic resonance imaging : JMRI Date A point or period of time associated with an event in the lifecycle of the resource 2018 2018-12 Subject The topic of the resource MRI; PI-RADS; prostate cancer; reader reproducibility Creator An entity primarily responsible for making the resource Smith Clayton P; Harmon Stephanie A; Barrett Tristan; Bittencourt Leonardo K; Law Yan Mee; Shebel Haytham; An Julie Y; Czarniecki Marcin; Mehralivand Sherif; Coskun Mehmet; Wood Bradford J; Pinto Peter A; Shih Joanna H; Choyke Peter L; Turkbey Baris Description An account of the resource BACKGROUND: The Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) has been in use since 2015; while interreader reproducibility has been studied, there has been a paucity of studies investigating the intrareader reproducibility of PI-RADSv2. PURPOSE: To evaluate both intra- and interreader reproducibility of Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/jmri.26555" target="_blank" rel="noreferrer noopener">10.1002/jmri.26555</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). 2018 An Julie Y Barrett Tristan Bittencourt Leonardo K Choyke Peter L Coskun Mehmet Czarniecki Marcin Harmon Stephanie A Journal of magnetic resonance imaging : JMRI Law Yan Mee Mehralivand Sherif MRI PI-RADS Pinto Peter A Prostate cancer reader reproducibility Shebel Haytham Shih Joanna H Smith Clayton P Turkbey Baris Wood Bradford J