Subject
Adult; Humans; Male; Chronic Disease; Immunohistochemistry; Follow-Up Studies; Biopsy; Risk Assessment; Amputation/methods; Osteomyelitis/*complications/*pathology; Patella/*pathology; Skin Neoplasms/etiology/*pathology/surgery; Carcinoma; Needle; Cell Transformation; Neoplastic/*pathology; Squamous Cell/etiology/*pathology/surgery