1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
85-88
Issue
2
Volume
10
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Role Of Urokinase Pais In The Control Of Cancer Invasion And Metastasis
Publisher
An entity responsible for making the resource available
Drug News & Perspectives
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
1997-03
Subject
The topic of the resource
adenocarcinomas; angiogenesis; cells; degradation; inhibition; in-vitro; migration; Pharmacology & Pharmacy; plasminogen-activator; receptor; tumor-metastasis
Creator
An entity primarily responsible for making the resource
Evans D M; Sloan-Stakleff K
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1997
adenocarcinomas
angiogenesis
Cells
degradation
Drug News & Perspectives
Evans D M
in-vitro
inhibition
migration
Pharmacology & Pharmacy
plasminogen-activator
Receptor
Sloan-Stakleff K
tumor-metastasis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
460-464
Issue
5
Volume
66
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Suppression Of The Invasive Capacity Of Human Breast Cancer Cells By Inhibition Of Urokinase Plasminogen Activator Via Amiloride And B428
Publisher
An entity responsible for making the resource available
American Surgeon
Date
A point or period of time associated with an event in the lifecycle of the resource
2000
2000-05
Subject
The topic of the resource
angiogenesis; carcinoma; integrins; migration; prevention; prognostic marker; proliferation; pulmonary metastases; receptor; Surgery; tumor-cells
Creator
An entity primarily responsible for making the resource
Evans D M; Sloan-Stakleff K
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2000
American Surgeon
angiogenesis
Carcinoma
Evans D M
integrins
migration
Prevention
prognostic marker
proliferation
pulmonary metastases
Receptor
Sloan-Stakleff K
Surgery
tumor-cells
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
353–357
Issue
4
Volume
16
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Time and dose dependency of the suppression of pulmonary metastases of rat mammary cancer by amiloride.
Publisher
An entity responsible for making the resource available
Clinical & experimental metastasis
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1998-05
Subject
The topic of the resource
Female; Animals; Rats; Drug Administration Schedule; Antineoplastic Agents/*administration & dosage; Neoplasm Transplantation; Amiloride/*administration & dosage; Lung Neoplasms/pathology/*prevention & control/*secondary; Plasminogen Activators/antagonists & inhibitors; Urokinase-Type Plasminogen Activator/antagonists & inhibitors; Dose-Response Relationship; Drug; Mammary Neoplasms; Experimental/*pathology; Inbred F344
Creator
An entity primarily responsible for making the resource
Evans D M; Sloan-Stakleff K; Arvan M; Guyton D P
Description
An account of the resource
Amiloride is an inhibitor of urokinase plasminogen activator (uPA), an essential component of the plasminogen/plasmin enzyme system. Inhibition of uPA prevents the conversion of plasminogen to tumor cell surface bound plasmin which is required for initiation of the metastatic process. MATB rat mammary cancer cells were introduced into the jugular venous system of 80 Fisher 344 female rats. Amiloride at high and low dosages was administered in the drinking water at the time of, prior to or several days following the tumor cell inoculation and continued daily for 10 days post inoculation. Control rats were maintained on water alone. The middle lobe of the right lung was examined microscopically for numbers of metastases. Suppression of metastases was significant at high amiloride dosages in all groups, and at low dosage when administered prior to inoculation. We conclude that amiloride suppresses induced metastases of rat mammary cancer, the effect being dose- and time-dependent.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1998
Amiloride/*administration & dosage
Animals
Antineoplastic Agents/*administration & dosage
Arvan M
Clinical & experimental metastasis
Dose-Response Relationship
Drug
Drug Administration Schedule
Evans D M
Experimental/*pathology
Female
Guyton D P
Inbred F344
Lung Neoplasms/pathology/*prevention & control/*secondary
Mammary Neoplasms
Neoplasm Transplantation
Plasminogen Activators/antagonists & inhibitors
Rats
Sloan-Stakleff K
Urokinase-Type Plasminogen Activator/antagonists & inhibitors