Outcomes In Obese And Overweight Acute Myeloid Leukemia (aml) Patients Receiving Chemotherapy Dosed According To Actual Body Weight
Hematology
Gallagher E M; Earl M; Yeh J Y; Kusick K; Kruse J; Swann C; Smith A; Davis R; Advani A S; Kalaycio M; Copelan E A; Sekeres M A
Blood
2011
2011-11
Journal Article or Conference Abstract Publication
n/a
Student College Of Clinical Pharmacy Provides Education About Medications And Fall Risk For Akron Area Agency On Aging Care Managers
Pharmacology & Pharmacy
Fredrickson M E; Smith A; Gallegos P; Soric M; Fosnight S
Pharmacotherapy
2012
2012-10
Journal Article or Conference Abstract Publication
n/a
Systemic consequences of oxidative stress following aortic surgery correlate with the degree of antioxidant defenses
Surgery; oxygen; pulmonary-edema; Cardiovascular System & Cardiology; capacity; ischemia-reperfusion injury; radicals; lung injury; depletion; mediators; xanthine-oxidase
The purpose of this study was to correlate the preoperative level of antioxidant defenses, measured by the plasma total antioxidant capacity (TAC), to the degree of postoperative systemic inflammatory response, measured by the severity of pulmonary injury following elective aortic surgery. Twenty-four patients had TAC measured preoperatively and 24 hr postoperatively. Chest radiography and arterial blood gases were obtained preoperatively and serially during the first 24 hr after surgery. Using objective radiologic criteria and blood gas analysis, the degree of pulmonary edema and pulmonary dysfunction were quantified. All patients showed evidence of pulmonary dysfunction in the first 24 hr following surgery. Fifteen of the 24 patients showed radiographic evidence of noncardiogenic pulmonary edema in the immediate postoperative period. In this group, the TAC was lower than in those without pulmonary edema immediately following surgery (p = 0.03). Preoperative TAC was associated with the degree of pulmonary edema in the postoperative period (r = -0.372, p = 0.067). These results suggest that preoperative antioxidant supplementation may favorably impact the severity of systemic inflammatory response following ischemia and reperfusion injury. DOI: 10.1007/s100169910006.
Cornu-Labat G; Serra M; Smith A; McGregor W E; Kasirajan K; Hirko M K; Turner J J; Rubin J R
Annals of Vascular Surgery
2000
2000-01
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1007/s100169910006" target="_blank" rel="noreferrer noopener">10.1007/s100169910006</a>
Prospective cohort study of type 2 Diabetes Mellitus and the risk of Parkinson's disease
Geriatrics & Gerontology
Smith A; Driver J A; Buring J E; Gaziano J M; Kurth T; Logroscino G
Journal of the American Geriatrics Society
2008
2008-04
Journal Article
n/a
MICROGLIAL ACTIVATION AND THE IMMUNOINFLAMMATORY RESPONSE AFTER A MODERATE TRAUMATIC BRAIN INJURY
activation; General & Internal Medicine; inflammation; mice; neuron; Neurosciences & Neurology
Smith A; Crish S
Journal of Neurotrauma
2016
2016-07
Journal Article
n/a