Ectopic Thyroid Nodular Goiter Presenting As A Porta Hepatis Mass
Surgery
An ectopic thyroid goiter was found in a 58-year-old woman who presented with abdominal and low back pain, diarrhea, and generalized weakness. Initial workup, including abdominal CT scan, revealed a mass extending from the duodenum to the porta hepatis. After resection and upon pathologic examination of the tissue, nodular arrangement of thyroid follicles and colloid lakes with focal hyperplastic and nodular goiter changes were identified.
Jamshidi M; Kasirye O; Smith D J
American Surgeon
1998
1998-04
Journal Article or Conference Abstract Publication
n/a
The Local Monoaminergic Dependency Of Spinal Ketamine
(intrathecal); 5-ht (5-hydroxytryptamine; analgesia; antinociception; cord; inhibition; ketamine; neurons; norepinephrine; opiate; opioid receptors; optical isomers; pharmacology; Pharmacology & Pharmacy; rat-brain; receptor; serotonin; tail-flick test
Crisp T; Perrotti J M; Smith D L; Stafinsky J L; Smith D J
European Journal of Pharmacology
1991
1991-03
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/0014-2999(91)90101-u" target="_blank" rel="noreferrer noopener">10.1016/0014-2999(91)90101-u</a>
EVALUATION OF THE INTERACTIONS OF SEROTONERGIC AND ADRENERGIC-DRUGS WITH MU, DELTA, AND KAPPA OPIOID BINDING-SITES
receptor; Neurosciences & Neurology; involvement; rat-brain; morphine; dorsal horn; adrenergic; cord; mu opioid; nociceptive; periaqueductal gray; phentolamine; raphe magnus stimulation; reflexes; serotonergic; spinal antinociceptive action; spiroxatrine; delta opioid; kappa opioid
Several serotonergic and adrenergic agents were tested for an ability to interact with mu, delta, and kappa opioid binding sites. Spiroxatrine interacted nearly equipotently with all three opioid subtypes, yielding K(i) values near 110 nM. A number of other serotonergic and adrenergic agents interacted with affinities in the 1-50-mu-M range. Most of the other compounds tested in this study were found to compete for opioid binding to some degree, though not achieving a 50% inhibition of binding at concentrations up to 100-mu-M. If this interaction between monoaminergic agents and opioid receptors is found to have functional significance, it must be considered in the interpretation of results from studies using these agents to evaluate the contribution of monoaminergic systems to opioid-mediated events.
Monroe P J; Perschke S E; Crisp T; Smith D J
Neuroscience Letters
1991
1991-12
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/0304-3940(91)90576-f" target="_blank" rel="noreferrer noopener">10.1016/0304-3940(91)90576-f</a>
Acute mesenteric vein thrombosis and pancreatitis
Physiology; Endocrinology & Metabolism; pancreatitis; intestinal ischemia; mesenteric vein thrombosis
This article presents a case of acute mesenteric vein thrombosis with small bowel infarction associated with pancreatitis. Although a rare occurrence, the authors suggest this diagnosis should be considered as a possible complication of pancreatic inflammation.
Cornu-Labat G; Kasirajan A; Simon R; Smith D J; Herman M L; Rubin J R
International Journal of Pancreatology
1997
1997-06
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1007/bf02821611" target="_blank" rel="noreferrer noopener">10.1007/bf02821611</a>
Small-bowel perforation secondary to metastatic carcinoma of the breast
Surgery
Perforation from a solitary metastatic lesion of the small bowel is rare. We report a case of acute perforation with no evidence of metastatic disease within the abdomen. Resection of the small bowel was performed.
Cornu-Labat G; Ghani A; Smith D J; McDonald A D; Kasirajan K
American Surgeon
1998
1998-04
Journal Article or Conference Abstract Publication
n/a