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Tags: Spin Labels

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Brain-targeted delivery of Tempol-loaded nanoparticles for neurological disorders.

Brain-targeted Tempol-loaded poly-(lactide-co-glycolide) (PLGA) nanoparticles (NPs) conjugated with a transferrin antibody (OX 26) were developed using the nanoprecipitation method. These NPs may have utility in treating neurodegenerative diseases…

Using O2 to probe membrane immersion depth by 19F NMR.

A fluorinated detergent, CF(3)(CF(2))(5)C(2)H(4)-O-maltose, was reconstituted into a lipid bilayer model membrane system to demonstrate the feasibility of determining solvent accessibility and membrane immersion depth of each fluorinated group by…

Tags: *Hydrocarbons, *Oxygen, 2000, Biological, Cyclic N-Oxides, Dimyristoylphosphatidylcholine/*chemistry, Fluorinated, Fluorine, Lipid Bilayers/*chemistry, Luchette P A, Magnetic Resonance Spectroscopy/*methods, Maltose/*analogs & derivatives, Models, Phospholipid Ethers/*chemistry, Pressure, Proceedings of the National Academy of Sciences of the United States of America, Prosser R S, Spin Labels, Westerman P W

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