1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/(sici)1097-4598(199712)20:12%3C1549::aid-mus10%3E3.0.co;2-w" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/(sici)1097-4598(199712)20:12%3C1549::aid-mus10%3E3.0.co;2-w</a>
Pages
1549–1560
Issue
12
Volume
20
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Afferent-inherent regulation of myosin heavy chain isoforms in rat muscle spindles.
Publisher
An entity responsible for making the resource available
Muscle & nerve
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
1997-12
Subject
The topic of the resource
Afferent Pathways/physiology; Afferent/*physiology; Animals; Denervation; Female; Ganglia; Ganglionectomy; Isomerism; Muscle Spindles/*metabolism; Myosin Heavy Chains/*metabolism; Neurons; Rats; Spinal Cord/physiology; Spinal/physiology; Sprague-Dawley; Toes/innervation
Creator
An entity primarily responsible for making the resource
Walro J M; Wang J; Story G M
Description
An account of the resource
Whether afferents exert their morphogenetic influence on spindles through release of trophic factors at intrafusal fiber junctions or via participation in proprioceptive pathways which modulate the motor activity to muscles was investigated by comparing myosin heavy chain (MHC) expression in intrafusal fibers after ablation of afferents (deafferentation, or DA) to the extensor digitorum longus (EDL) of adult rats or after ablation of the corresponding central processes of afferents to the spinal cord (central-process ablation, or CPA). DA and CPA elicited an exaggerated pedal plantarflexion, and hypertrophy of the EDL concomitant with atrophy of the soleus in the affected hindlimb. Frequencies and patterns of expression of seven MHCs expressed by intrafusal fibers in CPA muscles were indistinguishable from normal rats. However, frequencies and patterns of expression of several MHCs were abnormal following DA. Thus factors transported anterogradely from afferents to intrafusal fibers may regulate MHC expression in intrafusal fibers.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/(sici)1097-4598(199712)20:12%3C1549::aid-mus10%3E3.0.co;2-w" target="_blank" rel="noreferrer noopener">10.1002/(sici)1097-4598(199712)20:12%3C1549::aid-mus10%3E3.0.co;2-w</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1997
Afferent Pathways/physiology
Afferent/*physiology
Animals
Denervation
Female
Ganglia
Ganglionectomy
Isomerism
Muscle & nerve
Muscle Spindles/*metabolism
Myosin Heavy Chains/*metabolism
Neurons
Rats
Spinal Cord/physiology
Spinal/physiology
Sprague-Dawley
Story G M
Toes/innervation
Walro J M
Wang J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/jnr.490310412" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jnr.490310412</a>
Pages
678–692
Issue
4
Volume
31
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Inhibition of nerve growth factor-stimulated neurite outgrowth by methylamine-modified alpha 2-macroglobulin.
Publisher
An entity responsible for making the resource available
Journal of neuroscience research
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-04
Subject
The topic of the resource
alpha-Macroglobulins/metabolism/*pharmacology; Animals; Cells; Chick Embryo; Cultured; Drug Interactions; Female; Ganglia; Humans; Male; Methylamines/*pharmacology; Mice; Nerve Growth Factors/antagonists & inhibitors/metabolism/*pharmacology; Neurites/drug effects/*physiology/ultrastructure; Neurons/cytology/physiology; Placenta; Pregnancy; Spinal/physiology; Submandibular Gland
Creator
An entity primarily responsible for making the resource
Koo P H; Liebl D J
Description
An account of the resource
alpha 2-Macroglobulin (alpha 2M) is a rather ubiquitous protein in extracellular spaces of mammals. It is an inhibitor of endopeptidases, can be modified by aliphatic amines, and combines with a number of hormones/cytokines such as beta-nerve growth factor (NGF) [Koo PH, Stach RW (1989): J Neurosci Res 22:247]. The objective of this study is to compare the NGF-binding properties of methylamine-modified human alpha 2M (MA-alpha 2M) versus normal alpha 2M and their effects on the biological activity of NGF and neurite extension by embryonic chicken dorsal root ganglia. As determined by gel filtration, polyacrylamide gel electrophoresis, and equilibrium binding studies, these two forms of alpha 2M are similar in their binding affinities, with MA-alpha 2M binding about twice as much NGF as normal alpha 2M. Both normal alpha 2M and
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/jnr.490310412" target="_blank" rel="noreferrer noopener">10.1002/jnr.490310412</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
alpha-Macroglobulins/metabolism/*pharmacology
Animals
Cells
Chick Embryo
Cultured
Drug Interactions
Female
Ganglia
Humans
Journal of neuroscience research
Koo P H
Liebl D J
Male
Methylamines/*pharmacology
Mice
Nerve Growth Factors/antagonists & inhibitors/metabolism/*pharmacology
Neurites/drug effects/*physiology/ultrastructure
Neurons/cytology/physiology
Placenta
Pregnancy
Spinal/physiology
Submandibular Gland
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/002215540405201001" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/002215540405201001</a>
Pages
1249–1258
Issue
10
Volume
52
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The role of sensory neurons in cervical ripening: effects of estrogen and neuropeptides.
Publisher
An entity responsible for making the resource available
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-10
Subject
The topic of the resource
Afferent/metabolism/*physiology; Cervical Ripening/*physiology; Cervix Uteri/innervation; Estrogen/physiology; Estrogens/*physiology; Female; Ganglia; Humans; Neurons; Neuropeptides/biosynthesis/*physiology; Pregnancy; Receptors; Spinal/physiology
Creator
An entity primarily responsible for making the resource
Mowa C N; Papka R E
Description
An account of the resource
Central nervous system nuclei and circuits, such as the medial preoptic, ventromedial and paraventricular nuclei of the hypothalamus, play important roles in reproduction and parturition, and are influenced by estrogen. Peripheral autonomic and sensory neurons also play important roles in pregnancy and parturition. Moreover, the steroid hormone estrogen acts directly, not only on the reproductive tract organs (uterus and cervix), but also on the central and peripheral nerves by regulating expression of various neuronal genes. The peripheral primary afferent neurons innervating the uterine cervix relay mechanical and biochemical sensory information induced by local cervical events and by passage of fetuses, to the spinal cord and supraspinal centers. Consequently, the birth process in mammals is influenced by the combined action of neurons and hormones. Peripheral sensory stimuli, induced physiologically by fetal expulsion or mechanically by vaginocervical stimulation, alter behavior, as well as autonomic and neuroendocrine systems. Recent evidence indicates that primary afferent neurons innervating the cervix, in addition to their sensory effects, likely exert local "efferent" actions on the ripening cervix near term. These efferent effects may involve estrogen-regulated production of such neuropeptides as substance P and calcitonin gene-related peptide in lumbosacral dorsal root ganglia, and their release in the cervix. Collectively, these findings suggest an interrelationship among estrogen, cervix-related sensory neurons, and local cervical events near term.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/002215540405201001" target="_blank" rel="noreferrer noopener">10.1177/002215540405201001</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2004
Afferent/metabolism/*physiology
Cervical Ripening/*physiology
Cervix Uteri/innervation
Estrogen/physiology
Estrogens/*physiology
Female
Ganglia
Humans
Mowa C N
Neurons
Neuropeptides/biosynthesis/*physiology
Papka R E
Pregnancy
Receptors
Spinal/physiology
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society