1
40
12
-
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URL
https://doi.org/10.1002/jez.2574
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Title
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Robust locomotor performance of squirrel monkeys (Saimiri boliviensis) in response to simulated changes in support diameter and compliance
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Nicole M Schapker
Brad A Chadwell
Jesse W Young
Date
A point or period of time associated with an event in the lifecycle of the resource
2022
Description
An account of the resource
Arboreal environments require overcoming navigational challenges not typically encountered in other terrestrial habitats. Supports are unevenly distributed and vary in diameter, orientation, and compliance. To better understand the strategies that arboreal animals use to maintain stability in this environment, laboratory researchers must endeavor to mimic those conditions. Here, we evaluate how squirrel monkeys (Saimiri boliviensis) adjust their locomotor mechanics in response to variation in support diameter and compliance. We used high-speed cameras to film two juvenile female monkeys as they walked across poles of varying diameters (5, 2.5, and 1.25 cm). Poles were mounted on either a stiff wooden base ("stable" condition) or foam blocks ("compliant" condition). Six force transducers embedded within the pole trackway recorded substrate reaction forces during locomotion. We predicted that squirrel monkeys would walk more slowly on narrow and compliant supports and adopt more "compliant" gait mechanics, increasing stride lengths, duty factors, and an average number of limbs gripping the support, while the decreasing center of mass height, stride frequencies, and peak forces. We observed few significant adjustments to squirrel monkey locomotor kinematics in response to changes in either support diameter or compliance, and the changes we did observe were often tempered by interactions with locomotor speed. These results differ from a similar study of common marmosets (i.e., Callithrix jacchus, with relatively poor grasping abilities), where variation in diameter and compliance substantially impacted gait kinematics. Squirrel monkeys' strong grasping apparatus, long and mobile tails, and other adaptations for arboreal travel likely facilitate robust locomotor performance despite substrate precarity.
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J Exp Zool A Ecol Integr Physiol
. 2022 Jun;337(5):417-433. doi: 10.1002/jez.2574. Epub 2022 Jan 5.
Language
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English
2022
Balance
Branch stiffness
Fine branch niche
Locomotion
Stability
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/icb/icab096" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/icb/icab096</a>
ISSN
1557-7023 1540-7063
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Update Year & Number
June 2021 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Anatomy & Neurobiology
NEOMED Student Publications
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The stabilizing function of the tail during arboreal quadrupedalism.
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Integrative And Comparative Biology
Date
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2021
2021-05-22
Subject
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angular momentum; balance; locomotor biomechanics; primates; Stability
Creator
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Young JW; Chadwell BA; Dunham NT; McNamara A; Phelps T; Hieronymous TL; Shapiro LJ
Description
An account of the resource
Locomotion on the narrow and compliant supports of the arboreal environment is inherently precarious. Previous studies have identified a host of morphological and behavioral specializations in arboreal animals broadly thought to promote stability when on precarious substrates. Less well-studied is the role of the tail in maintaining balance. However, prior anatomical studies have found that arboreal taxa frequently have longer tails for their body size than their terrestrial counterparts, and prior laboratory studies of tail kinematics and the effects of tail reduction in focal taxa have broadly supported the hypothesis that the tail is functionally important for maintaining balance on narrow and mobile substrates. In the current set of studies, we extend this work in two ways. First, we use a laboratory dataset on three-dimensional segmental kinematics and tail inertial properties in squirrel monkeys (Saimiri boliviensis) to investigate how tail angular momentum is modulated during steady-state locomotion on narrow supports. In the second study, we use a quantitative dataset on quadrupedal locomotion in wild platyrrhine monkeys to investigate how free-ranging arboreal animals adjust tail movements in response to substrate variation, focusing on kinematic measures validated in prior laboratory studies of tail mechanics (including the laboratory data presented). Our laboratory results show that S. boliviensis significantly increase average tail angular momentum magnitudes and amplitudes on narrow supports, and primarily regulate that momentum by adjusting the linear and angular velocity of the tail (rather than via changes in tail posture per se). We build on these findings in our second study by showing that wild platyrrhines responded to the precarity of narrow and mobile substrates by extending the tail and exaggerating tail displacements, providing ecological validity to the laboratory studies of tail mechanics presented here and elsewhere. In conclusion, our data support the hypothesis that the long and mobile tails of arboreal animals serve a biological role of enhancing stability when moving quadrupedally over narrow and mobile substrates. Tail angular momentum could be used to cancel out the angular momentum generated by other parts of the body during steady-state locomotion, thereby reducing whole-body angular momentum and promoting stability, and could be used to mitigate the effects of destabilizing torques about the support should the animals encounter large, unexpected perturbations. Overall, these studies suggest that long and mobile tails should be considered among the fundamental suite of adaptations promoting safe and efficient arboreal locomotion.
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<a href="http://doi.org/10.1093/icb/icab096" target="_blank" rel="noreferrer noopener">10.1093/icb/icab096</a>
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journalArticle
2021
angular momentum
Balance
Chadwell BA
Department of Anatomy & Neurobiology
Dunham NT
Hieronymous TL
Integrative and comparative biology
journalArticle
June 2021 List
locomotor biomechanics
McNamara A
NEOMED College of Medicine
NEOMED Student Publications
Phelps T
Primates
Shapiro LJ
Stability
Young JW
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1242/jeb.217562" target="_blank" rel="noreferrer noopener">http://doi.org/10.1242/jeb.217562</a>
ISSN
1477-9145 0022-0949
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Update Year & Number
June 2020 Update II
NEOMED College
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Department of Anatomy & Neurobiology
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Asymmetrical gait kinematics of free-ranging callitrichines in response to changes in substrate diameter and orientation.
Publisher
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The Journal of experimental biology
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-05-15
Subject
The topic of the resource
locomotion; Primate; Stability
Creator
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Dunham Noah T; McNamara Allison; Shapiro Liza J; Phelps Taylor; Young Jesse W
Description
An account of the resource
Arboreal environments present considerable biomechanical challenges for animals moving and foraging among substrates varying in diameter, orientation, and compliance. Most studies of quadrupedal gait kinematics in primates and other arboreal mammals have focused on symmetrical walking gaits and the significance of diagonal sequence gaits. Considerably less research has examined asymmetrical gaits, despite their prevalence in small-bodied arboreal taxa. Here we examine whether and how free-ranging callitrichine primates adjust asymmetrical gait kinematics to changes in substrate diameter and orientation, as well as how variation in gait kinematics affects substrate displacement. We used high-speed video to film free-ranging Saguinus tripartitus and Cebuella pygmaea inhabiting the Tiputini Biodiversity Station, Ecuador. We found that Saguinus used bounding and half-bounding gaits on larger substrates versus gallops and symmetrical gaits on smaller substrates, and also shifted several kinematic parameters consistent with attenuating forces transferred from the animal to the substrate. Similarly, Cebuella shifted from high impact bounding gaits on larger substrates to using more half-bounding gaits on smaller substrates; however, kinematic adjustments to substrate diameter were not as profound as in Saguinus Both species adjusted gait kinematics to changes in substrate orientation; however, gait kinematics did not significantly affect empirical measures of substrate displacement in either species. Due to their small body size, claw-like nails, and reduced grasping capabilities, callitrichines arguably represent extant biomechanical analogues for an early stage in primate evolution. As such, greater attention should be placed on understanding asymmetrical gait dynamics for insight into hypotheses concerning early primate locomotor evolution.
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<a href="http://doi.org/10.1242/jeb.217562" target="_blank" rel="noreferrer noopener">10.1242/jeb.217562</a>
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Format
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journalArticle
2020
Department of Anatomy & Neurobiology
Dunham Noah T
journalArticle
June 2020 Update II
Locomotion
McNamara Allison
NEOMED College of Medicine Student
NEOMED Student Publications
Phelps Taylor
Primate
Shapiro Liza J
Stability
The Journal of experimental biology
Young Jesse W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jhevol.2020.102767" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jhevol.2020.102767</a>
Pages
102767
Volume
142
ISSN
1095-8606 0047-2484
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Update Year & Number
June 2020 Update II
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Anatomy & Neurobiology
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Not all fine-branch locomotion is equal: Grasping morphology determines locomotor performance on narrow supports.
Publisher
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Journal of human evolution
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-05
Subject
The topic of the resource
angular-momentum; arboreal locomotion; body-size; Fine-branch niche; Marmosets; minutus rodentia muridae; positional behavior; Primate origins; Primate origins; quadrupedal locomotion; Squirrel monkeys; Squirrel monkeys; Squirrel monkeys; Squirrels; Stability; substrate use; trade-offs
Creator
An entity primarily responsible for making the resource
Young Jesse W; Chadwell Brad A
Description
An account of the resource
Fine-branch models have long played a central role in primate evolutionary research. Nevertheless, recent studies of positional behavior in nonprimate arboreal mammals have challenged the idea that synapomorphic primate features, such as grasping extremities, uniquely facilitated access to the fine-branch zone. We test the alternative hypothesis that grasping extremities specifically improve locomotor performance in a fine-branch environment by examining how support diameter influences locomotor mechanics in one sciurid rodent (Sciurus carolinensis) and two platyrrhine primates (Callithrix jacchus and Saimiri boliviensis). These species were chosen to broadly model different stages in the evolution of primate grasping morphology. The results showed that transitioning from broad to narrower supports required the greatest kinematic adjustment in squirrels and the least adjustment in squirrel monkeys, with marmosets displaying an intermediate level of adjustment. Moreover, on any given support, squirrels' locomotor mechanics differed from marmosets' in a manner consistent with a greater need for stability, despite superficial ecomorphological similarities between sciurid rodents and callitrichine primates. Morphological analyses of autopodial size and proportions suggest that variation in locomotor performance more closely tracked variation in overall hand and foot size rather than digit length per se. Indeed, a broad comparative analysis revealed that for their body mass, primates have longer hands than similarly sized arboreal rodents and marsupials (although only the primate-rodent comparison was significant after incorporating phylogenetic relatedness). Inclusion of fossil stem primates (plesiadapiforms) and euprimates (adapiforms) in these analyses suggests that this primate-wide grade shift in relative autopodial size must have occurred early in the evolutionary history of the group. Overall, our findings show that basal primate morphological adaptations may have specifically facilitated improved locomotor performance in a fine-branch niche, rather than merely permitting access to the environment. As such, future adaptive hypotheses of primate origins should incorporate the import of primate-like morphology on locomotor performance as well.
Identifier
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<a href="http://doi.org/10.1016/j.jhevol.2020.102767" target="_blank" rel="noreferrer noopener">10.1016/j.jhevol.2020.102767</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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journalArticle
2020
angular-momentum
arboreal locomotion
body-size
Chadwell Brad A
Department of Anatomy & Neurobiology
Fine-branch niche
Journal of human evolution
journalArticle
June 2020 Update II
marmosets
minutus rodentia muridae
NEOMED College of Medicine
Positional behavior
Primate origins
quadrupedal locomotion
Squirrel monkeys
SQUIRRELS
Stability
substrate use
trade-offs
Young Jesse W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2146/ajhp100214" target="_blank" rel="noreferrer noopener">http://doi.org/10.2146/ajhp100214</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
69-72
Issue
1
Volume
68
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Title
A name given to the resource
Stability Of Extemporaneously Prepared Acetylcysteine 1% And 10% Solutions For Treatment Of Meconium Ileus
Publisher
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American Journal of Health-System Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011-01
Subject
The topic of the resource
Acetylcysteine; Chromatography; Color; Compounding; Concentration; cystic fibrosis; Diluents; edta; equivalent; Hydrogen ion concentration; Hydrogen sulfide; Ileus; Infant; liquid; management; Mucolytic agents; n-acetylcysteine; nonoperative treatment; obstruction; Odors; Pharmacology & Pharmacy; Sodium chloride; Stability; Storage
Creator
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Fohl A L; Johnson C E; Cober M P
Identifier
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<a href="http://doi.org/10.2146/ajhp100214" target="_blank" rel="noreferrer noopener">10.2146/ajhp100214</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2011
Acetylcysteine
American Journal of Health-System Pharmacy
Chromatography
Cober M P
Color
compounding
Concentration
CYSTIC fibrosis
Department of Pharmacy Practice
Diluents
edta
equivalent
Fohl A L
hydrogen ion concentration
Hydrogen sulfide
Ileus
Infant
Johnson C E
Liquid
Management
Mucolytic agents
n-acetylcysteine
NEOMED College of Pharmacy
nonoperative treatment
obstruction
Odors
Pharmacology & Pharmacy
Sodium chloride
Stability
Storage
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/1069072708329035" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/1069072708329035</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
189-200
Issue
2
Volume
17
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Title
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Personality, Vocational Interests, And Work Values Of Medical Students
Publisher
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Journal of Career Assessment
Date
A point or period of time associated with an event in the lifecycle of the resource
2009
2009-05
Subject
The topic of the resource
career specialty choice; dissatisfaction; interests; Medical students; neo-pi-r; personality; physicians; Psychology; satisfaction; selection; Stability; traits; values
Creator
An entity primarily responsible for making the resource
Duffy R D; Borges N J; Hartung P J
Identifier
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<a href="http://doi.org/10.1177/1069072708329035" target="_blank" rel="noreferrer noopener">10.1177/1069072708329035</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2009
Borges N J
Career specialty choice
Department of Family & Community Medicine
dissatisfaction
Duffy R D
Hartung P J
Interests
Journal of Career Assessment
medical students
neo-pi-r
NEOMED College of Medicine
Personality
Physicians
Psychology
satisfaction
Selection
Stability
traits
values
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2146/ajhp090505" target="_blank" rel="noreferrer noopener">http://doi.org/10.2146/ajhp090505</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1195-1198
Issue
14
Volume
67
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Dublin Core
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Title
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Physical Compatibility Of 4% Sodium Citrate With Selected Antimicrobial Agents
Publisher
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American Journal of Health-System Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2010
2010-07
Subject
The topic of the resource
Aminoglycosides; antibiotic-lock technique; antibiotics; Anticoagulants; Antiinfective agents; catheter-related infection; Concentration; Daptomycin; Gentamicin; hemodialysis; Hydrogen ion concentration; Incompatibilities; Injections; Linezolid; management; Pharmacology & Pharmacy; Photodecomposition; Precipitation; prevention; Sodium citrate; Spectrometry; Stability; Storage; Temperature; Tobramycin; Turbidity; Vancomycin
Creator
An entity primarily responsible for making the resource
Dotson B; Lynn S; Savakis K; Churchwell M D
Identifier
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<a href="http://doi.org/10.2146/ajhp090505" target="_blank" rel="noreferrer noopener">10.2146/ajhp090505</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2010
American Journal of Health-System Pharmacy
Aminoglycosides
antibiotic-lock technique
Antibiotics
Anticoagulants
Antiinfective Agents
catheter-related infection
Churchwell M D
Concentration
Daptomycin
Dotson B
Gentamicin
Hemodialysis
hydrogen ion concentration
Incompatibilities
Injections
Linezolid
Lynn S
Management
Pharmacology & Pharmacy
Photodecomposition
Precipitation
Prevention
Savakis K
Sodium citrate
Spectrometry
Stability
Storage
Temperature
Tobramycin
Turbidity
vancomycin
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2146/100247" target="_blank" rel="noreferrer noopener">http://doi.org/10.2146/100247</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
843-845
Issue
9
Volume
68
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Title
A name given to the resource
Stability of extemporaneously prepared glycopyrrolate oral suspensions
Publisher
An entity responsible for making the resource available
American Journal of Health-System Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011-05
Subject
The topic of the resource
Color; Chromatography; Suspensions; Taste; Pharmacology & Pharmacy; liquid; Stability; Compounding; Concentration; Contamination; Glycopyrrolate; Hydrogen ion concentration; Parasympatholytic agents; sialorrhea; Storage; Vehicles
Creator
An entity primarily responsible for making the resource
Cober M P; Johnson C E; Sudekum D; Penprase K
Description
An account of the resource
Purpose. The stability of extemporaneously prepared glycopyrrolate 0.5-mg/mL suspensions was evaluated. Methods. An oral suspension of glycopyrrolate 0.5 mg/mL was prepared by thoroughly grinding 30 1-mg tablets of glycopyrrolate in a glass mortar. Thirty milliliters of Ora-Plus and 30 mL of either Ora-Sweet or Ora-Sweet SF were mixed and added to the powder to make a final volume of 60 mL. Three identical samples of the formulation were prepared and placed in 2-oz amber plastic bottles with child-resistant caps and stored at room temperature (23-25 degrees C). A 1-mL sample was withdrawn from each of the three bottles with a micropipette immediately after preparation and 7, 15, 30, 60, and 90 days afterward. After further dilution to an expected concentration of 50 mu g/mL with sample diluent, the samples were assayed in duplicate by stability-indicating high-performance liquid chromatography. The samples were visually examined for any color change and evaluated for pH on each day of analysis. Taste evaluations were performed at the beginning and end of the study. Stability was defined as the retention of at least 90% of the initial concentration. Results. At least 95% of the initial glycopyrrolate remained throughout the 90-day study period in both preparations. There were no detectable changes in color, odor, taste, and pH, and no visible microbial growth was observed in any sample. Conclusion. Extemporaneously compounded suspensions of glycopyrrolate 0.5 mg/mL in a 1:1 mixture of Ora-Plus/Ora-Sweet or Ora-Plus/Ora-Sweet SF were stable for at least 90 days when stored in amber plastic bottles at room temperature.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.2146/100247" target="_blank" rel="noreferrer noopener">10.2146/100247</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2011
American Journal of Health-System Pharmacy
Chromatography
Cober M P
Color
compounding
Concentration
Contamination
Department of Pharmacy Practice
Glycopyrrolate
hydrogen ion concentration
Johnson C E
Journal Article or Conference Abstract Publication
Liquid
NEOMED College of Pharmacy
Parasympatholytic agents
Penprase K
Pharmacology & Pharmacy
sialorrhea
Stability
Storage
Sudekum D
Suspensions
Taste
Vehicles
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1117/12.2293992" target="_blank" rel="noreferrer noopener">http://doi.org/10.1117/12.2293992</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Volume
10575
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Empirical Evaluation of Cross-Site Reproducibility in Radiomic Features for Characterizing Prostate MRI
Publisher
An entity responsible for making the resource available
Medical Imaging 2018: Computer-Aided Diagnosis
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018
Subject
The topic of the resource
mri; Stability; prostate; feature analysis; multi-site; radiomics; reproducibility; variance
Creator
An entity primarily responsible for making the resource
Chirra P; Leo P; Yim M; Bloch B N; Rastinehad A R; Purysko A; Rosen M; Madabhushi A; Viswanath S
Description
An account of the resource
The recent advent of radiomics has enabled the development of prognostic and predictive tools which use routine imaging, but a key question that still remains is how reproducible these features may be across multiple sites and scanners. This is especially relevant in the context of MRI data, where signal intensity values lack tissue specific, quantitative meaning, as well as being dependent on acquisition parameters (magnetic field strength, image resolution, type of receiver coil). In this paper we present the first empirical study of the reproducibility of 5 different radiomic feature families in a multi-site setting; specifically, for characterizing prostate MRI appearance. Our cohort comprised 147 patient T2w MRI datasets from 4 different sites, all of which were first pre-processed to correct acquisition-related for artifacts such as bias field, differing voxel resolutions, as well as intensity drift (non-standardness). 406 3D voxel wise radiomic features were extracted and evaluated in a cross-site setting to determine how reproducible they were within a relatively homogeneous non-tumor tissue region; using 2 different measures of reproducibility: Multivariate Coefficient of Variation and Instability Score. Our results demonstrated that Haralick features were most reproducible between all 4 sites. By comparison, Laws features were among the least reproducible between sites, as well as performing highly variably across their entire parameter space. Similarly, the Gabor feature family demonstrated good cross-site reproducibility, but for certain parameter combinations alone. These trends indicate that despite extensive pre-processing, only a subset of radiomic features and associated parameters may be reproducible enough for use within radiomics-based machine learning classifier schemes.
Identifier
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<a href="http://doi.org/10.1117/12.2293992" target="_blank" rel="noreferrer noopener">10.1117/12.2293992</a>
Format
The file format, physical medium, or dimensions of the resource
Book Chapter
2018
Bloch B N
Book Chapter
Chirra P
feature analysis
Leo P
Madabhushi A
Medical Imaging 2018: Computer-Aided Diagnosis
MRI
multi-site
Prostate
Purysko A
radiomics
Rastinehad A R
reproducibility
Rosen M
Stability
variance
Viswanath S
Yim M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/107110070302400405" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/107110070302400405</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
332-337
Issue
4
Volume
24
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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First metatarsal-phalangeal joint arthrodesis: A biomechanical assessment of stability
Publisher
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Foot & Ankle International
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003-04
Subject
The topic of the resource
1st metatarsophalangeal joint; biomechanical testing; first metatarsal phalangeal joint arthrodesis; fixation; hallux rigidus; hallux valgus; Orthopedics; plate; rheumatoid-arthritis; stability
Creator
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Politi J; Hayes J; Njus G; Bennett G L; Kay D B
Description
An account of the resource
Background: First metatarsal phalangeal joint (MTP) arthrodesis is a commonly performed procedure for the treatment of hallux rigidus, severe and recurrent bunion deformities, rheumatoid arthritis and other less common disorders of the joint. There are different techniques of fixation of the joint to promote arthrodesis including oblique lag screw fixation, lag screw and dorsal plate fixation, crossed Kirschner wires, dorsal plate fixation alone and various types of external fixation. Ideally the fixation method should be reproducible, lead to a high rate of fusion, and have a low incidence of complications. Methods: In the present study, we compared the strength of fixation of five commonly utilized techniques of first MTP joint arthrodesis. These were: 1. Surface excision with machined conical reaming and fixation with a 3.5 mm cortical interfragmentary lag screw. 2. Surface excision with machined conical reaming and fixation with crossed 0.062 Kirschner wires. 3. Surface excision with machined conical reaming and fixation with a 3.5 mm cortical lag screw and a four hole dorsal miniplate secured with 3.5 mm cortical screws. 4. Surface excision with machined conical reaming and fixation with a four hole dorsal miniplate secured with 3.5 mm cortical screws and no lag screw. 5. Planar surface excision and fixation with a single oblique 3.5 mm interfragmentary cortical lag screw. Testing was done on an Instron materials testing device loading the first MTP joint in dorsiflexion. Liquid metal strain gauges were placed over the joint and micromotion was detected with varying loads and cycles. Results: The most stable technique was the combination of machined conical reaming and an oblique interfragmentary lag screw and dorsal plate. This was greater than two times stronger than an oblique lag screw alone. Dorsal plate alone and Kirschner wire fixation were the weakest techniques. Conclusions: First MTP fusion is a commonly performed procedure for the treatment of a variety of disorders of the first MTP joint. The most stable technique for obtaining fusion in this study was the combination of an oblique lag screw and a dorsal plate. This should lead to higher rates of arthrodesis.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/107110070302400405" target="_blank" rel="noreferrer noopener">10.1177/107110070302400405</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1st metatarsophalangeal joint
2003
Bennett G L
biomechanical testing
first metatarsal phalangeal joint arthrodesis
Fixation
Foot & ankle international
hallux rigidus
hallux valgus
Hayes J
Journal Article
Kay D B
Njus G
Orthopedics
plate
Politi J
rheumatoid-arthritis
Stability
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/ajhp/zxz174" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/ajhp/zxz174</a>
Pages
1492-1510
Issue
19
Volume
76
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Title
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Enteral and parenteral nutrition considerations in pediatric patients
Publisher
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American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-09
Subject
The topic of the resource
compounding; enteral; neonatal; nutrition; parenteral; pediatric; stability
October 2019 Update
Creator
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Cober Mary Petrea; Gura Kathleen M
Description
An account of the resource
PURPOSE: Current clinical practice guidelines on management of enteral nutrition (EN) and parenteral nutrition (PN) in pediatric patients are reviewed. SUMMARY: The provision of EN and PN in pediatric patients poses many unique considerations and challenges. Although indications for use of EN and PN are similar in adult and pediatric populations, recommended EN and PN practices differ for pediatric versus adult patients in areas such as selection of EN and PN formulations, timing of EN and PN initiation, advancement of nutrition support, and EN and PN goals. Additionally, provision of EN and PN to pediatric patients poses unique compounding and medication administration challenges. This article provides a review of current EN and PN best practices and special nutrition considerations for neonates, infants, and other pediatric patients. CONCLUSION: The provision of EN and PN to pediatric patients presents many unique challenges. It is important for pharmacists to keep current with pediatric- and neonatal-specific guidelines on nutritional management of various disease states, as well as strategies to address compounding and medication administration challenges, in order to optimize EN and PN outcomes.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/ajhp/zxz174" target="_blank" rel="noreferrer noopener">10.1093/ajhp/zxz174</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2019
American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists
Cober Mary Petrea
compounding
Department of Pharmacy Practice
enteral
Gura Kathleen M
NEOMED College of Pharmacy
Neonatal
nutrition
October 2019 Update
Parenteral
Pediatric
Stability
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1117/1.JMI.6.2.024502" target="_blank" rel="noreferrer noopener">http://doi.org/10.1117/1.JMI.6.2.024502</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
024502-024502
Issue
2
Volume
6
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Multisite evaluation of radiomic feature reproducibility and discriminability for identifying peripheral zone prostate tumors on MRI
Publisher
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Journal of Medical Imaging (Bellingham, Wash.)
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
The topic of the resource
discriminability; feature analysis; magnetic resonance imaging; multisite; prostate; radiomics; reproducibility; stability
Creator
An entity primarily responsible for making the resource
Chirra Prathyush; Leo Patrick; Yim Michael; Bloch B Nicolas; Rastinehad Ardeshir R; Purysko Andrei; Rosen Mark; Madabhushi Anant; Viswanath Satish E
Description
An account of the resource
Recent advances in the field of radiomics have enabled the development of a number of prognostic and predictive imaging-based tools for a variety of diseases. However, wider clinical adoption of these tools is contingent on their generalizability across multiple sites and scanners. This may be particularly relevant in the context of radiomic features derived from T1- or T2-weighted magnetic resonance images (MRIs), where signal intensity values are known to lack tissue-specific meaning and vary based on differing acquisition protocols between institutions. We present the first empirical study of benchmarking five different radiomic feature families in terms of both reproducibility and discriminability in a multisite setting, specifically, for identifying prostate tumors in the peripheral zone on MRI. Our cohort comprised 147 patient T2-weighted MRI datasets from four different sites, all of which are first preprocessed to correct for acquisition-related artifacts such as bias field, differing voxel resolutions, and intensity drift (nonstandardness). About 406 three-dimensional voxel-wise radiomic features from five different families (gray, Haralick, gradient, Laws, and Gabor) were evaluated in a cross-site setting to determine (a) how reproducible they are within a relatively homogeneous nontumor tissue region and (b) how well they could discriminate tumor regions from nontumor regions. Our results demonstrate that a majority of the popular Haralick features are reproducible in over 99% of all cross-site comparisons, as well as achieve excellent cross-site discriminability (classification accuracy of ≈ 0.8 ). By contrast, a majority of Laws features are highly variable across sites (reproducible in < 75 % of all cross-site comparisons) as well as resulting in low cross-site classifier accuracies ( < 0.6 ), likely due to a large number of noisy filter responses that can be extracted. These trends suggest that only a subset of radiomic features and associated parameters may be both reproducible and discriminable enough for use within machine learning classifier schemes.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1117/1.JMI.6.2.024502" target="_blank" rel="noreferrer noopener">10.1117/1.JMI.6.2.024502</a>
2019
Bloch B Nicolas
Chirra Prathyush
discriminability
feature analysis
Journal of Medical Imaging (Bellingham
Journal of Medical Imaging (Bellingham, Wash.)
Leo Patrick
Madabhushi Anant
Magnetic Resonance Imaging
multisite
NEOMED College of Medicine Student
NEOMED Student Publications
Prostate
Purysko Andrei
radiomics
Rastinehad Ardeshir R
reproducibility
Rosen Mark
September 2019 Update
Stability
Viswanath Satish E
Wash.)
Yim Michael