Cardiovascular complications of cocaine abuse.
*Cocaine/adverse effects/analogs & derivatives/metabolism; Adult; Cardiomyopathies/etiology; Coronary Disease/etiology; Ethanol/metabolism; Heart Diseases/*etiology; Humans; Myocardial Infarction/etiology; Neurotransmitter Uptake Inhibitors/adverse effects; Substance-Related Disorders/*complications
Cocaine abuse may lead to serious cardiac complications, including myocardial ischemia and infarction, myocarditis, cardiomyopathy and arrhythmias. With concomitant use of alcohol and cocaine, cocaethylene is produced by hepatic transformation. Cocaethylene is now thought to be primarily responsible for the deaths that occur among cocaine abusers. Treatment of cardiovascular complications focuses on cocaine-induced ischemia, hypertension and arrhythmias. The use of thrombolytic agents in myocardial infarction remains controversial. Concurrent detoxification with bromocriptine and norepinephrine is recommended.
Bunn W H; Giannini A J
American Family Physician
1992
1992-09
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1007/978-1-4899-1648-8_17" target="_blank" rel="noreferrer noopener">10.1007/978-1-4899-1648-8_17</a>
From Boundary Spanning to Deep Partnerships.
*Cooperative Behavior; *Criminal Behavior; *Interdisciplinary Communication; *Interprofessional Relations; Humans; Mental Disorders/*complications; Substance-Related Disorders/*complications
Munetz Mark R; Bonfine Natalie
Psychiatric services (Washington, D.C.)
2015
2015-09
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1176/appi.ps.660902" target="_blank" rel="noreferrer noopener">10.1176/appi.ps.660902</a>