Browse Items (4 total)
- Tags: Superoxides/metabolism
Increased mitochondrial prooxidant activity mediates up-regulation of Complex I
Tags: *Up-Regulation, 2015, Animals, Chen Chwen-Lih, Chen Yeong-Renn, Complex I, Department of Integrative Medical Sciences, Electron Spin Resonance Spectroscopy, eNOS(-/-) murine heart, Free radical biology & medicine, Glutathione/*metabolism, Heart/*metabolism, Kang Patrick T, Knockout, Mice, Mitochondria, Myocardium/enzymology/*metabolism, NEOMED College of Medicine, Nitric Oxide Synthase Type III/genetics/*metabolism, Oxidation-Reduction, Oxidative Stress, Protein thiyl radical, Reactive Oxygen Species/*metabolism, S-Glutathionylation, Superoxides/metabolism
Protein thiyl radical mediates S-glutathionylation of complex I.
Tags: *Oxidative Stress, 2012, Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Cattle, Cell Line, Chen Chwen-Lih, Chen Jingfeng, Chen Yeong-Renn, Cyclic N-Oxides/chemistry/pharmacology, Cysteine/chemistry/*metabolism, Department of Integrative Medical Sciences, Electron Transport Complex I/chemistry/*metabolism, Free radical biology & medicine, Free Radical Scavengers/chemistry/pharmacology, Free Radicals/chemistry/*metabolism, Glutathione/chemistry/*metabolism, Green Kari B, Heart/enzymology/metabolism, Kang Patrick T, Mice, Mitochondria, Models, Molecular, Molecular Sequence Data, Muscle Cells/drug effects/metabolism, NEOMED College of Medicine, Onium Compounds/pharmacology, Peptide Fragments/chemistry, Peptide Mapping, Protein, Rats, Rotenone/pharmacology, Structural Homology, Superoxides/metabolism, Zhang Liwen
Vitamin B12 protects against superoxide-induced cell injury in human aortic endothelial cells.
Tags: 2011, Aorta/pathology, Apoptosis/drug effects, Atherosclerosis/*drug therapy/metabolism/pathology/physiopathology, Brasch Nicola E, Cell Line, Cell Survival/drug effects, Cytoprotection, Department of Integrative Medical Sciences, Endothelium, Free radical biology & medicine, Free Radical Scavengers/*pharmacology, Humans, Mitochondria/drug effects/metabolism/pathology, Moreira Edward S, NEOMED College of Medicine, Oxidative Stress/drug effects, Reperfusion Injury/*drug therapy/metabolism/pathology/physiopathology, Superoxides/metabolism, Vascular/*drug effects/metabolism/pathology, Vitamin B 12/*pharmacology, Vitamin B Complex/*pharmacology, Yun June
Impairment of pH gradient and membrane potential mediates redox dysfunction in the mitochondria of the post-ischemic heart.
Tags: *Energy Metabolism, *Membrane potential, *Mitochondria, *Myocardial ischemia and reperfusion, *Oxidative Stress, *pH gradient, *Redox dysfunction, 2017, Aconitate Hydratase/metabolism, Animal, Animals, Basic research in cardiology, Cell Line, Chen Chwen-Lih, Chen Yeong-Renn, Chilian William M, Department of Family & Community Medicine, Department of Integrative Medical Sciences, Disease Models, Electron Transport Chain Complex Proteins/metabolism, Heart/*metabolism/pathology, Hydrogen Peroxide/metabolism, Hydrogen-Ion Concentration, Ionophores/pharmacology, Kang Patrick T, Lin Paul, Male, Mitochondria, Mitochondrial, Myocardial Infarction/*metabolism/pathology, Myocardium/*metabolism/pathology, NEOMED College of Medicine, Oxidation-Reduction, Potassium/metabolism, Rats, Sprague-Dawley, Superoxides/metabolism