1
40
7
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0361-9230(91)90228-c" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0361-9230(91)90228-c</a>
Pages
211–214
Issue
2
Volume
26
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Ontogenesis of the depressant activity of carbachol on synaptic activity in rat visual cortex.
Publisher
An entity responsible for making the resource available
Brain research bulletin
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991-02
Subject
The topic of the resource
Animals; Rats; Synapses/drug effects/*physiology; Carbachol/*pharmacology; Visual Cortex/drug effects/metabolism/*physiology; Receptors; Muscarinic/drug effects/metabolism
Creator
An entity primarily responsible for making the resource
Vaknin G; Teyler T J
Description
An account of the resource
We studied the ontogeny of muscarinic depression in the developing rat visual cortex using carbachol (a nonhydrolyzable cholinergic agonist) application to neocortical slices obtained from four postnatal age groups: 9-10 days, 15 days,
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0361-9230(91)90228-c" target="_blank" rel="noreferrer noopener">10.1016/0361-9230(91)90228-c</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1991
Animals
Brain research bulletin
Carbachol/*pharmacology
Muscarinic/drug effects/metabolism
Rats
Receptors
Synapses/drug effects/*physiology
Teyler T J
Vaknin G
Visual Cortex/drug effects/metabolism/*physiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0892-0362(88)90090-6" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0892-0362(88)90090-6</a>
Pages
539–548
Issue
6
Volume
10
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Triethyltin exposure suppresses synaptic transmission in area CA1 of the rat hippocampal slice.
Publisher
An entity responsible for making the resource available
Neurotoxicology and teratology
Date
A point or period of time associated with an event in the lifecycle of the resource
1988
1988-12
Subject
The topic of the resource
Female; Animals; Rats; In Vitro Techniques; Synapses/drug effects/*physiology; Evoked Potentials/drug effects; Synaptic Transmission/*drug effects; Hippocampus/drug effects/*pathology/physiology; Pyramidal Tracts/drug effects/*pathology/physiology; Trialkyltin Compounds/*toxicity; Triethyltin Compounds/*toxicity
Creator
An entity primarily responsible for making the resource
Fountain S B; Ting Y L; Hennes S K; Teyler T J
Description
An account of the resource
To examine the effects of TET on the electrophysiology of area CA1 of hippocampus, hippocampal slices were obtained from adult hooded rats and were maintained in vitro using standard techniques. Stimulating and recording electrodes were placed in the Schaffer collaterals and CA1 pyramidal cell body layer, respectively. Following baseline measurements, slices were exposed to either 0, 1, 3, 6, or 10 microM TET in the incubating medium. Both pyramidal cell excitability and recurrent/feedforward inhibition were suppressed in a dose-dependent manner within 3 hr postexposure. The evoked population spike and population excitatory postsynaptic potential (EPSP) were suppressed significantly by 2 hr postexposure for 1 and 3 microM TET exposures, and by 45 min postexposure for 6 and 10 microM exposures. A similar dose-dependency was observed for the suppression of recurrent/feedforward inhibition in hippocampal CA1. A second procedure tested the specificity of TET effects to axonal conduction of Schaffer collaterals. Both the stimulating and recording electrode were placed in the Schaffer collaterals so that both the Schaffer collateral population fiber volley and the CA1 pyramidal cell population EPSP could be recorded. TET exposure suppressed pyramidal cell EPSPs without significantly affecting the amplitude of Schaffer collateral fiber volleys. The results support the view that acute TET exposure suppresses synaptic transmission in area CA1 of hippocampus.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0892-0362(88)90090-6" target="_blank" rel="noreferrer noopener">10.1016/0892-0362(88)90090-6</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1988
Animals
Evoked Potentials/drug effects
Female
Fountain S B
Hennes S K
Hippocampus/drug effects/*pathology/physiology
In Vitro Techniques
Neurotoxicology and teratology
Pyramidal Tracts/drug effects/*pathology/physiology
Rats
Synapses/drug effects/*physiology
Synaptic Transmission/*drug effects
Teyler T J
Ting Y L
Trialkyltin Compounds/*toxicity
Triethyltin Compounds/*toxicity
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3389/fncir.2013.00175" target="_blank" rel="noreferrer noopener">http://doi.org/10.3389/fncir.2013.00175</a>
Pages
175–175
Volume
7
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
High concentrations of divalent cations isolate monosynaptic inputs from local circuits in the auditory midbrain.
Publisher
An entity responsible for making the resource available
Frontiers in neural circuits
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
1905-07
Subject
The topic of the resource
inferior colliculus; Animals; Mice; Acoustic Stimulation; Neural Inhibition/drug effects/*physiology; high divalents; local circuits; monosynaptic; first spike latency; Inferior Colliculi/drug effects/*physiology; Reaction Time/drug effects/physiology; Synapses/drug effects/*physiology; Cations; Divalent/*pharmacology
Creator
An entity primarily responsible for making the resource
Sivaramakrishnan Shobhana; Sanchez Jason Tait; Grimsley Calum Alex
Description
An account of the resource
Hierarchical processing of sensory information occurs at multiple levels between the peripheral and central pathway. Different extents of convergence and divergence in top down and bottom up projections makes it difficult to separate the various components activated by a sensory input. In particular, hierarchical processing at sub-cortical levels is little understood. Here we have developed a method to isolate extrinsic inputs to the inferior colliculus (IC), a nucleus in the midbrain region of the auditory system, with extensive ascending and descending convergence. By applying a high concentration of divalent cations (HiDi) locally within the IC, we isolate a HiDi-sensitive from a HiDi-insensitive component of responses evoked by afferent input in brain slices and in vivo during a sound stimulus. Our results suggest that the HiDi-sensitive component is a monosynaptic input to the IC, while the HiDi-insensitive component is a local polysynaptic circuit. Monosynaptic inputs have short latencies, rapid rise times, and underlie first spike latencies. Local inputs have variable delays and evoke long-lasting excitation. In vivo, local circuits have variable onset times and temporal profiles. Our results suggest that high concentrations of divalent cations should prove to be a widely useful method of isolating extrinsic monosynaptic inputs from local circuits in vivo.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3389/fncir.2013.00175" target="_blank" rel="noreferrer noopener">10.3389/fncir.2013.00175</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2013
Acoustic Stimulation
Animals
Cations
Divalent/*pharmacology
first spike latency
Frontiers in neural circuits
Grimsley Calum Alex
high divalents
Inferior Colliculi/drug effects/*physiology
inferior colliculus
local circuits
Mice
monosynaptic
Neural Inhibition/drug effects/*physiology
Reaction Time/drug effects/physiology
Sanchez Jason Tait
Sivaramakrishnan Shobhana
Synapses/drug effects/*physiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0304-3940(93)90166-i" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0304-3940(93)90166-i</a>
Pages
39–42
Issue
1
Volume
154
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Role of adenosine in heterosynaptic, posttetanic depression in area CA1 of hippocampus.
Publisher
An entity responsible for making the resource available
Neuroscience letters
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-05
Subject
The topic of the resource
Adenosine/*physiology; Afferent/drug effects/physiology; Animals; Dendrites/drug effects/physiology; Electric Stimulation; Evoked Potentials/drug effects/physiology; Hippocampus/cytology/drug effects/*physiology; In Vitro Techniques; Neuronal Plasticity/drug effects/physiology; Neurons; Purinergic Antagonists; Rats; Synapses/drug effects/*physiology; Synaptic Transmission/drug effects/physiology; Theophylline/analogs & derivatives/pharmacology; Xanthines/pharmacology
Creator
An entity primarily responsible for making the resource
Grover L M; Teyler T J
Description
An account of the resource
Conditioning stimulation of afferent fibers in hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of responses evoked by stimulation of an independent set of afferent fibers. PTD was present within 5 s of conditioning stimulation, amounted to a 60-80% reduction of excitatory postsynaptic potentials (EPSPs), and required a period of 3-5 min for recovery. Antagonists of A1 adenosine receptors substantially reduced PTD. Adenosine released into, or formed in, the extracellular space during conditioning stimulation may diffuse within the slice to depress evoked release of glutamate.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0304-3940(93)90166-i" target="_blank" rel="noreferrer noopener">10.1016/0304-3940(93)90166-i</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Adenosine/*physiology
Afferent/drug effects/physiology
Animals
Dendrites/drug effects/physiology
Electric Stimulation
Evoked Potentials/drug effects/physiology
Grover L M
Hippocampus/cytology/drug effects/*physiology
In Vitro Techniques
Neuronal Plasticity/drug effects/physiology
Neurons
Neuroscience letters
Purinergic Antagonists
Rats
Synapses/drug effects/*physiology
Synaptic Transmission/drug effects/physiology
Teyler T J
Theophylline/analogs & derivatives/pharmacology
Xanthines/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0006-8993(94)91335-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0006-8993(94)91335-8</a>
Pages
353–356
Issue
2
Volume
647
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Spermine depresses NMDA, K/AMPA and GABAA-mediated synaptic transmission in the rat hippocampal slice preparation.
Publisher
An entity responsible for making the resource available
Brain research
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-06
Subject
The topic of the resource
AMPA/antagonists & inhibitors; Animals; Calcium Channels/drug effects; Evoked Potentials/drug effects; Excitatory Amino Acid Antagonists/*pharmacology; GABA-A Receptor Antagonists; Hippocampus/drug effects/*physiology; In Vitro Techniques; N-Methyl-D-Aspartate/antagonists & inhibitors; Rats; Receptors; Spermine/*pharmacology; Synapses/drug effects/*physiology; Synaptic Transmission/*drug effects
Creator
An entity primarily responsible for making the resource
DiScenna P G; Ferchmin P A; Eterovic V A; Teyler T J
Description
An account of the resource
The effects of spermine, an endogenous polyamine, were examined in area CA1 of the rat hippocampal slice preparation. Spermine, at low millimolar concentrations, rapidly and potently depressed NMDA and K/AMPA-mediated population EPSPs, and GABA-mediated monosynaptic population IPSPs. These effects contrast with its well-known potentiation of NMDA currents at lower concentrations. Our results raise the possibility that the large intracellular stores of spermine that are released after various neural insults could act as an endogenous neuroprotective mechanism by limiting excessive calcium entry.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0006-8993(94)91335-8" target="_blank" rel="noreferrer noopener">10.1016/0006-8993(94)91335-8</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
AMPA/antagonists & inhibitors
Animals
Brain research
Calcium Channels/drug effects
DiScenna P G
Eterovic V A
Evoked Potentials/drug effects
Excitatory Amino Acid Antagonists/*pharmacology
Ferchmin P A
GABA-A Receptor Antagonists
Hippocampus/drug effects/*physiology
In Vitro Techniques
N-Methyl-D-Aspartate/antagonists & inhibitors
Rats
Receptors
Spermine/*pharmacology
Synapses/drug effects/*physiology
Synaptic Transmission/*drug effects
Teyler T J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/syn.890150207" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/syn.890150207</a>
Pages
149–157
Issue
2
Volume
15
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Presynaptic mechanism for heterosynaptic, posttetanic depression in area CA1 of rat hippocampus.
Publisher
An entity responsible for making the resource available
Synapse (New York, N.Y.)
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-10
Subject
The topic of the resource
Afferent/drug effects; Animals; Electric Stimulation; Electrophysiology; Evoked Potentials/physiology; Glutamate/drug effects; Glutamates/pharmacology; Glutamic Acid; Hippocampus/drug effects/*physiology; In Vitro Techniques; Membrane Potentials/physiology; N-Methyl-D-Aspartate/antagonists & inhibitors; Neuronal Plasticity/drug effects/physiology; Neurons; Presynaptic/drug effects/*physiology; Pyramidal Cells/drug effects; Rats; Receptors; Synapses/drug effects/*physiology
Creator
An entity primarily responsible for making the resource
Grover L M; Teyler T J
Description
An account of the resource
Conditioning stimulation applied to afferent fibers in stratum radiatum or stratum oriens of hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of excitatory postsynaptic potentials (EPSPs). PTD amounted to a
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/syn.890150207" target="_blank" rel="noreferrer noopener">10.1002/syn.890150207</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Afferent/drug effects
Animals
Electric Stimulation
Electrophysiology
Evoked Potentials/physiology
Glutamate/drug effects
Glutamates/pharmacology
Glutamic Acid
Grover L M
Hippocampus/drug effects/*physiology
In Vitro Techniques
Membrane Potentials/physiology
N-Methyl-D-Aspartate/antagonists & inhibitors
Neuronal Plasticity/drug effects/physiology
Neurons
Presynaptic/drug effects/*physiology
Pyramidal Cells/drug effects
Rats
Receptors
Synapse (New York, N.Y.)
Synapses/drug effects/*physiology
Teyler T J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/hipo.450040602" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/hipo.450040602</a>
Pages
623–634
Issue
6
Volume
4
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Multideterminant role of calcium in hippocampal synaptic plasticity.
Publisher
An entity responsible for making the resource available
Hippocampus
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-12
Subject
The topic of the resource
Animals; Calcium/*physiology; Hippocampus/drug effects/*physiology; Humans; Neuronal Plasticity/drug effects/*physiology; Synapses/drug effects/*physiology
Creator
An entity primarily responsible for making the resource
Teyler T J; Cavus I; Coussens C; DiScenna P; Grover L; Lee Y P; Little Z
Description
An account of the resource
Hippocampal CA1 cells possess several varieties of long-lasting synaptic plasticity: two different forms of long-term potentiation (LTP) and at least one form of long-term depression (LTD). All forms of synaptic plasticity are induced by afferent activation, all involve Ca2+ influx, all can be blocked by Ca2+ chelators, and all activate Ca(2+)-dependent mechanisms. The question arises as how different physiological responses can be initiated by activation of the same second messenger. We consider two hypotheses which could account for these phenomena: voltage-dependent differences in cytosolic Ca2+ concentration acting upon Ca2+ substrates of differing Ca2+ affinities and compartmentalization of the Ca2+ and its substrates.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/hipo.450040602" target="_blank" rel="noreferrer noopener">10.1002/hipo.450040602</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
Animals
Calcium/*physiology
Cavus I
Coussens C
DiScenna P
Grover L
Hippocampus
Hippocampus/drug effects/*physiology
Humans
Lee Y P
Little Z
Neuronal Plasticity/drug effects/*physiology
Synapses/drug effects/*physiology
Teyler T J