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Text
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URL Address
<a href="http://doi.org/10.3390/microorganisms8040490" target="_blank" rel="noreferrer noopener">http://doi.org/10.3390/microorganisms8040490</a>
Issue
4
Volume
8
ISSN
2076-2607 2076-2607
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.3390/microorganisms8040490" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.3390/microorganisms8040490</a>
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Update Year & Number
June 2020 Update I
NEOMED College
NEOMED College of Medicine
NEOMED Department
NEOMED Student Publications
Dublin Core
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Title
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The Microbiota-Gut-Brain Axis Heart Shunt Part I: The French Paradox, Heart Disease and the Microbiota.
Publisher
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Microorganisms
Date
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2020
2020-03-30
Subject
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Alzheimer; blood brain barrier; Celiac disease; cerebrovascular; co-metabolism; French paradox; heart brain shunt; HMG-Co A; leaky gut; microbiota-gut-brain axis; polyphenol; red wine; redox; TMANO; TMAO; Trimethyl-Amine-N-Oxide; vascular dementia
Creator
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Obrenovich Mark; Siddiqui Bushra; McCloskey Benjamin; Reddy V Prakash
Description
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It has been well established that a vegetarian and polyphenol-rich diet, including fruits, vegetables, teas, juices, wine, indigestible fiber and whole grains, provide health-promoting phytochemicals and phytonutrients that are beneficial for the heart and brain. What is not well-characterized is the affect these foods have when co-metabolized within our dynamic gut and its colonizing flora. The concept of a heart shunt within the microbiota-gut-brain axis underscores the close association between brain and heart health and the so-called "French paradox" offers clues for understanding neurodegenerative and cerebrovascular diseases. Moreover, oxidation-redox reactions and redox properties of so-called brain and heart-protective foods are underappreciated as to their enhanced or deleterious mechanisms of action. Focusing on prodromal stages, and common mechanisms underlying heart, cerebrovascular and neurodegenerative diseases, we may unmask and understanding the means to better treat these related diseases.
Identifier
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<a href="http://doi.org/10.3390/microorganisms8040490" target="_blank" rel="noreferrer noopener">10.3390/microorganisms8040490</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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journalArticle
2020
Alzheimer
blood brain barrier
celiac disease
cerebrovascular
co-metabolism
French paradox
heart brain shunt
HMG-Co A
Journal Article
journalArticle
June 2020 Update I
leaky gut
McCloskey Benjamin
microbiota-gut-brain axis
microorganisms
NEOMED College of Medicine Student
NEOMED Student Publications
Obrenovich Mark
polyphenol
red wine
Reddy V Prakash
Redox
Siddiqui Bushra
TMANO
TMAO
Trimethyl-Amine-N-Oxide
vascular dementia