1
40
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Text
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<a href="http://doi.org/10.12659/AJCR.926064" target="_blank" rel="noreferrer noopener">http://doi.org/10.12659/AJCR.926064</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
e926064
Volume
21
ISSN
1941-5923 1941-5923
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Update Year & Number
October 2020 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Mercy Health St Elizabeth Youngstown Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Suspected levetiracetam-induced rhabdomyolysis: A case report and literature review.
Publisher
An entity responsible for making the resource available
The American Journal of Case Reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-10-28
Subject
The topic of the resource
Seizures; Rhabdomyolysis; Creatine Kinase
Creator
An entity primarily responsible for making the resource
Moinuddin IA
Description
An account of the resource
BACKGROUND Levetiracetam (LEV) is an anticonvulsant commonly used for treatment of generalized and partial seizure disorder. Some of the common side effects associated with levetiracetam include somnolence, dizziness, headaches, and mood changes. Rhabdomyolysis and increase in creatine kinase (CK) levels is one of the rarely reported effects of LEV. CASE REPORT We report a case of a 22-year-old man admitted for evaluation of new-onset generalized tonic-clonic seizures. The patient was started on levetiracetam 500 mg twice a day, after which his CK levels started to increase, with maximum level of 21 936 IU/L noted on day 5. No improvement in CK levels was observed even with aggressive intravenous hydration. In the absence of any other obvious cause, the persistent elevation in patient's CK levels was suspected to be due to LEV. Our suspicion was supported by significant decrease in CK levels (from 21 936 IU/L to 11 337 IU/L) after about 30 h of discontinuation of LEV. We reviewed cases of LEV-induced rhabdomyolysis reported in the literature over the last decade and found 13 cases with almost similar correlation between initiation of LEV and increase in CK levels. CONCLUSIONS Our case report stresses the importance of close monitoring of CK levels and kidney functions after initiation of LEV, and to consider changing the anticonvulsant medication if CK levels are noted to be significantly high to avoid kidney injury.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.12659/AJCR.926064" target="_blank" rel="noreferrer noopener">10.12659/AJCR.926064</a>
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The file format, physical medium, or dimensions of the resource
journalArticle
2020
Creatine Kinase
Department of Internal Medicine
journalArticle
Mercy Health St Elizabeth Youngstown Hospital
Moinuddin IA
NEOMED College of Medicine
October 2020 List
Rhabdomyolysis
Seizures
The American journal of case reports
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.12659/AJCR.913207" target="_blank" rel="noreferrer noopener">http://doi.org/10.12659/AJCR.913207</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
111-116
Volume
20
Dublin Core
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Title
A name given to the resource
Olmesartan Associated Enteropathy: A Rare Underdiagnosed Cause of Diarrhea and Weight Loss.
Publisher
An entity responsible for making the resource available
The American journal of case reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-01
Subject
The topic of the resource
Humans; Male; Middle Aged; Colitis; *Weight Loss; Antihypertensive Agents/*adverse effects; Diarrhea/*chemically induced; Imidazoles/*adverse effects; Tetrazoles/*adverse effects; Vomiting/*chemically induced; Lymphocytic/*chemically induced
Creator
An entity primarily responsible for making the resource
Gonakoti Sripriya; Khullar Sanjiv; Rajkumar Aarthi
Description
An account of the resource
BACKGROUND Olmesartan, an angiotensin receptor blockade class of antihypertensive medication has recently been associated with a seronegative sprue like enteropathy. Patients typically present with diarrhea and weight loss often prompting exhaustive diagnostic workup. Discontinuation of the drug leads to dramatic recovery and hence, physicians need to be aware of olmesartan associated enteropathy (OAE) in order to avoid unnecessary testing. CASE REPORT A
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.12659/AJCR.913207" target="_blank" rel="noreferrer noopener">10.12659/AJCR.913207</a>
*Weight Loss
2019
Antihypertensive Agents/*adverse effects
Colitis
Department of Internal Medicine
Diarrhea/*chemically induced
Gonakoti Sripriya
Humans
Imidazoles/*adverse effects
Khullar Sanjiv
Lymphocytic/*chemically induced
Male
Middle Aged
NEOMED College of Medicine
Rajkumar Aarthi
Tetrazoles/*adverse effects
The American journal of case reports
Vomiting/*chemically induced
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.12659/AJCR.913207" target="_blank" rel="noreferrer noopener">http://doi.org/10.12659/AJCR.913207</a>
Pages
111–116
Volume
20
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Olmesartan Associated Enteropathy: A Rare Underdiagnosed Cause of Diarrhea and Weight Loss.
Publisher
An entity responsible for making the resource available
The American journal of case reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-01
Creator
An entity primarily responsible for making the resource
Gonakoti Sripriya; Khullar Sanjiv; Rajkumar Aarthi
Description
An account of the resource
BACKGROUND Olmesartan, an angiotensin receptor blockade class of antihypertensive medication has recently been associated with a seronegative sprue like enteropathy. Patients typically present with diarrhea and weight loss often prompting exhaustive diagnostic workup. Discontinuation of the drug leads to dramatic recovery and hence, physicians need to be aware of olmesartan associated enteropathy (OAE) in order to avoid unnecessary testing. CASE REPORT A
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.12659/AJCR.913207" target="_blank" rel="noreferrer noopener">10.12659/AJCR.913207</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2019
Department of Internal Medicine
Gonakoti Sripriya
Khullar Sanjiv
NEOMED College of Medicine
Rajkumar Aarthi
The American journal of case reports
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.12659/ajcr.903176" target="_blank" rel="noreferrer noopener">http://doi.org/10.12659/ajcr.903176</a>
Pages
334–338
Volume
18
Dublin Core
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Title
A name given to the resource
Gall Bladder Agenesis: A Rare Embryonic Cause of Recurrent Biliary Colic.
Publisher
An entity responsible for making the resource available
The American journal of case reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-04
Subject
The topic of the resource
Female; Humans; Young Adult; Recurrence; Rare Diseases; Gallbladder/*abnormalities; *Congenital Abnormalities; Biliary Tract Diseases/*etiology; Colic/*etiology
Creator
An entity primarily responsible for making the resource
Rajkumar Aarthi; Piya Albina
Description
An account of the resource
BACKGROUND Gallbladder agenesis (GA) is an extremely rare anatomic anomaly with a reported incidence of less than 0.5%. It is usually asymptomatic, but can present with features of biliary colic and cholecystitis. We present here a case of GA in a patient with recurrent biliary colic. CASE REPORT A 24-year-old African American woman presented with recurrent episodes of right upper-quadrant abdominal pain. During her first episode, she was found to have elevated transaminases and clinical features of cholecystitis, but ultrasound did not visualize a gallbladder and she was discharged with a diagnosis of biliary colic. She returned within a week with worsening liver enzymes, severe pain, and vomiting. A hepatobiliary iminodiacetic acid (HIDA) scan was done, which again did not show the gall bladder. On clinical suspicion of acute cholecystitis, she underwent laparoscopic surgery. Intraoperatively, the gall bladder fossa was empty and a diagnosis of gall bladder agenesis was made. She presented a third time with similar complaints and magnetic resonance cholangiopancreatography (MRCP) was done, which showed normal biliary tract anatomy and absent gall bladder. A diagnosis of sphincter of Oddi dysfunction was made and she was discharged on antispasmodics. CONCLUSIONS Diagnosing GA is challenging. The rarity of this entity combined with classic clinical features of cholecystitis and non-visualization of the gall bladder on routine investigation prompts unnecessary surgical intervention. Awareness of this condition, along with use of better imaging modalities like preoperative MRCP, can aide physicians to appropriately manage this uncommon clinical condition.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.12659/ajcr.903176" target="_blank" rel="noreferrer noopener">10.12659/ajcr.903176</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Congenital Abnormalities
2017
Biliary Tract Diseases/*etiology
Colic/*etiology
Female
Gallbladder/*abnormalities
Humans
Piya Albina
Rajkumar Aarthi
Rare Diseases
Recurrence
The American journal of case reports
Young Adult
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.12659/ajcr.900701" target="_blank" rel="noreferrer noopener">http://doi.org/10.12659/ajcr.900701</a>
Pages
869–873
Volume
17
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A Rare Case of Tubulointerstitial Nephritis and Uveitis Syndrome Treated with a Multi-Specialty Approach.
Publisher
An entity responsible for making the resource available
The American journal of case reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-11
Subject
The topic of the resource
Female; Humans; Young Adult; Follow-Up Studies; Biopsy; Glucocorticoids/administration & dosage; Kidney/*diagnostic imaging; Prednisolone/administration & dosage/*analogs & derivatives; Prednisone/*administration & dosage; Recurrence; Uveitis/diagnosis/*drug therapy; Diagnosis; Dose-Response Relationship; Drug; Differential; Drug Therapy; Combination; Interstitial/diagnosis/*drug therapy; Nephritis
Creator
An entity primarily responsible for making the resource
Purt Boonkit; Hiremath Siri; Smith Sarah; Erzurum Sergul; Sarac Erdal
Description
An account of the resource
BACKGROUND It is important for an ophthalmologist and nephrologist to look for hidden causes of uveitis and nephritis, respectively. Delay in diagnosis leads to increased morbidity and failure to systemically manage the patient results in future recurrence of disease. It is likely that TINU remains underdiagnosed and could potentially account for some of the cases of idiopathic uveitis, especially when greater than 50% of uveitis cases have no identifiable cause. Fewer than 300 cases of tubulointerstitial nephritis and uveitis (TINU) syndrome have been reported. In TINU syndrome, inflammation affects the renal tubules, interstitial tissue, and uveal tract. Its pathogenesis remains poorly understood. CASE REPORT We report a rare case of TINU syndrome in a 23-year-old female who was treated using a multispecialty approach. Her primary care physician diagnosed her with proteinuria and acute kidney injury and referred her to the nephrologist, who later referred her to the ophthalmologist. A left kidney biopsy confirmed acute interstitial nephritis. Following the discovery of a "pink eye", the patient was referred to ophthalmology and diagnosed with anterior uveitis, confirming TINU syndrome. Without the additional findings of uveitis, the diagnosis would have been missed. Resolution was obtained through steroid therapy. CONCLUSIONS Correctly diagnosing TINU syndrome requires a multispecialty approach and may not be obvious upon initial presentation. Therefore, the ophthalmologist needs to consider TINU in the differential diagnosis for a patient with bilateral uveitis and evaluate a urinalysis for proteinuria as part of the work up.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.12659/ajcr.900701" target="_blank" rel="noreferrer noopener">10.12659/ajcr.900701</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2016
Biopsy
Combination
Department of Internal Medicine
Diagnosis
Differential
Dose-Response Relationship
Drug
Drug Therapy
Erzurum Sergul
Female
Follow-Up Studies
Glucocorticoids/administration & dosage
Hiremath Siri
Humans
Interstitial/diagnosis/*drug therapy
Kidney/*diagnostic imaging
NEOMED College of Medicine
Nephritis
Prednisolone/administration & dosage/*analogs & derivatives
Prednisone/*administration & dosage
Purt Boonkit
Recurrence
Sarac Erdal
Smith Sarah
The American journal of case reports
Uveitis/diagnosis/*drug therapy
Young Adult