Browse Items · NEOMED Bibliography Database

Effectiveness of a group exercise program in a long-term care facility: a randomized pilot trial.

OBJECTIVE: The purpose of this pilot was to determine whether a strength and flexibility program in frail long-term care facility (LTC) residents would result in improved function. DESIGN: A prospective, randomized, controlled, semicrossover trial…

Relationship between breast cancer and meningioma.

Several authors have suggested the existence of a relationship between breast cancer and meningioma occurring in the same patient. I describe four patients who had both of these neoplasms and present findings that dispute the implied relationship…

Tags: 1992, Aged, Breast Neoplasms/*diagnosis, Carcinoma, Female, Humans, Intraductal, Meningeal Neoplasms/*diagnosis, Meningioma/*diagnosis, Middle Aged, Neoplasms, Noninfiltrating/*diagnosis, Ovarian Neoplasms/diagnosis, Second Primary/*diagnosis, Smith-Behn J, Southern medical journal, Time Factors

Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.

Cytochrome P450 (CYP) enzymes mediate mixed-function oxidation reactions important in drug metabolism. The aromatic heterocyclic cation, diphenyleneiodonium (DPI), binds flavin in cytochrome P450 reductase and inhibits

Recommendations for treatment of hospital-acquired and ventilator-associated pneumonia: review of recent international guidelines.

Recently published guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia are reviewed for recommendations regarding diagnosis and antimicrobial therapy to assess the implications for development of future…

Tags: *Practice Guidelines as Topic, 2010, Anti-Bacterial Agents/*therapeutic use, Bacteria/drug effects/isolation & purification, Bacterial/diagnosis/*drug therapy, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Clinical Trials as Topic, Cross Infection/diagnosis/*drug therapy, Department of Internal Medicine, File Thomas M Jr, Hospitals, Humans, Microbial Sensitivity Tests, NEOMED College of Medicine, Pneumonia, Time Factors, Ventilator-Associated/diagnosis/*drug therapy

What can we learn from the time course of untreated and partially treated community-onset Streptococcus pneumoniae pneumonia? A clinical perspective on superiority and noninferiority trial designs for mild community-acquired pneumonia.

There are no well-designed placebo-controlled clinical trials in the recent era that precisely define the magnitude of the drug effect of antimicrobial therapy for mild community-acquired pneumonia (CAP). However, there is evidence that ineffective…

Tags: *Research Design, 2008, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/*drug therapy/microbiology, Department of Internal Medicine, Disease Progression, File Thomas M Jr, Humans, NEOMED College of Medicine, Pneumococcal/*drug therapy/microbiology, Pneumonia, Randomized Controlled Trials as Topic/*methods, Schentag Jerome J, Streptococcus pneumoniae/*isolation & purification, Time Factors, Treatment Outcome

A multi-level modeling approach examining PTSD symptom reduction during prolonged exposure therapy: moderating effects of number of trauma types experienced, having an HIV-related index trauma, and years since HIV diagnosis among

People living with HIV (PLWH) have extensive interpersonal trauma histories and higher rates of posttraumatic stress disorder (PTSD) than the general population. Prolonged exposure (PE) therapy is efficacious in reducing PTSD across a variety of…

Tags: *HIV/AIDS, *prolonged exposure therapy, *PTSD, *trauma history, 2017, Adult, AIDS care, Boarts Jessica M, Ciesla Jeffrey A, Coleman Jennifer A, Delahanty Douglas L, Descriptive Statistics, Feeny Norah C, Female, HIV Infections/*psychology, HIV-Infected Patients – Psychosocial Factors, Human, Humans, Implosive Therapy/*methods, Jones Tracy, Junglen Angela G, LONGITUDINAL method, Male, Middle Aged, Pacella Maria L, Post-Traumatic – Symptoms, Post-Traumatic – Therapy, POST-traumatic stress disorder, Post-Traumatic/diagnosis/*psychology/*therapy, Prospective Studies, Psychological/*psychology/therapy, PSYCHOLOGY of HIV-positive people, Smith Brian C, Stress, Stress Disorders, Time, Time Factors, Trauma – Classification, Trauma – History, TREATMENT effectiveness, TREATMENT of post-traumatic stress disorder, Treatment Outcome, Treatment Outcomes – Evaluation, United States, WOUNDS & injuries – Classification, WOUNDS & injuries – History

A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.

Prox1, an early specific marker for developing liver and pancreas in foregut endoderm has recently been shown to interact with alpha-fetoprotein transcription factor and repress cholesterol 7alpha-hydroxylase (CYP7A1) gene transcription. Using a…

Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques

Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.

Bcl-2 is an anti-apoptotic protein that has recently been shown to regulate other cellular functions. We previously reported that Bcl-2 regulates chondrocyte matrix gene expression, independent of its anti-apoptotic function. Here, we further…

Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko

Prostate apoptosis response-4 enhances secretion of amyloid beta peptide 1-42 in human neuroblastoma IMR-32 cells by a caspase-dependent pathway.

Prostate apoptosis response-4 (Par-4) is a leucine zipper protein that promotes neuronal cell death in Alzheimer's disease (AD). Neuronal degeneration in AD may result from extracellular accumulation of amyloid beta peptide (Abeta) 1-42. To examine…

A comparison of costs associated with screening for gestational diabetes with two-tiered and one-tiered testing protocols.

OBJECTIVE: The Fourth International Workshop on Gestational Diabetes recently suggested that two techniques, a 2-tiered protocol and a 1-tiered protocol, to screen for gestational diabetes mellitus are acceptable alternatives. This study was…

Tags: 2001, American journal of obstetrics and gynecology, Cost-Benefit Analysis, Diabetes, Female, Gestational/*diagnosis/*economics, Glucose Tolerance Test/*economics/*methods, Humans, Lavin B, Lavin J P Jr, Mass Screening/economics, O'Donnell N, Pregnancy, Time Factors

Panniculectomy at the time of gynecologic surgery in morbidly obese patients.

OBJECTIVE: Our goal was to demonstrate that panniculectomy performed at the time of gynecologic surgery aids in reducing the operative time and exposure and does not increase the wound infection rate in morbidly obese patients. STUDY DESIGN: A…

Long-term evaluation of the long-pulsed alexandrite laser for the removal of bikini hair at shortened treatment intervals.

BACKGROUND: Laser-assisted hair removal is becoming the treatment of choice for removing unwanted hair. OBJECTIVE: The purpose of this work was to determine the long-term efficacy of the long-pulsed infrared (LPIR) laser at shortened treatment…

Tags: *Laser Therapy, 2000, Adolescent, Adult, Department of Internal Medicine, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], Female, Hair Removal/*methods, Humans, Lloyd J R, Male, Middle Aged, Mirkov Mirko, NEOMED College of Medicine, Time Factors, Treatment Outcome

Whales originated from aquatic artiodactyls in the Eocene epoch of India.

Although the first ten million years of whale evolution are documented by a remarkable series of fossil skeletons, the link to the ancestor of cetaceans has been missing. It was known that whales are related to even-toed ungulates (artiodactyls), but…

Two components of long-term potentiation induced by different patterns of afferent activation.

Long-term potentiation (LTP) of excitatory synaptic transmission could be a mechanism underlying memory. Induction of LTP requires Ca2+ influx into postsynaptic neurons through ion channels gated by NMDA (N-methyl-D-aspartate) receptors in…

Tags: 1990, 2-Amino-5-phosphonovalerate/*pharmacology, Afferent Pathways/physiology, Animals, Calcium/*physiology, Grover L M, Hippocampus/*physiology, In Vitro Techniques, Membrane Potentials, Memory/*physiology, N-Methyl-D-Aspartate/*physiology, Nature, Neuronal Plasticity, Receptors, Synaptic Transmission, Teyler T J, Time Factors

Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial.

BACKGROUND: Although repeat radiation treatment has been shown to palliate pain in patients with bone metastases from multiple primary origin sites, data for the best possible dose fractionation schedules are lacking. We aimed to assess two dose…

Tags: *Dose Fractionation, *Radiotherapy, 2014, Aged, Analgesics – Therapeutic Use, Analgesics/therapeutic use, Australia, Babington Scott, Bone Neoplasms, Bone Neoplasms – Complications, Bone Neoplasms – Radiotherapy, Bone Neoplasms/complications/*radiotherapy/*secondary, Brief pain inventory, Brundage Michael D, Canada, Cauda Equina, Chen Bingshu E, Chi Square Test, Chi-Square Distribution, Chow Edward, Clinical Assessment Tools, Clinical Trials, Computer-Assisted, Computer-Assisted – Adverse Effects, Computer-Assisted/adverse effects, Demas William F, Europe, Female, Fractures, Funding Source, Hartsell William F, Hoskin Peter, Human, Humans, Intention to Treat Analysis, Israel, Logistic Models, Logistic Regression, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, New Zealand, Odds Ratio, Oei Bing, Pain – Diagnosis, Pain – Drug Therapy, Pain – Etiology, Pain – Radiotherapy, Pain Measurement, Pain/diagnosis/drug therapy/*etiology/*radiotherapy, Questionnaires, Radiation, Radiation Dosage, Radiotherapy, Radiotherapy Planning, Risk Factors, Roos Daniel, Scales, Spinal Cord Compression – Etiology, Spinal Cord Compression/etiology, Spontaneous – Etiology, Spontaneous/etiology, Surveys and Questionnaires, The Lancet. Oncology, Time Factors, Tissing-Tan Caroline J A, Treatment Outcome, Treatment Outcomes, van der Linden Yvette M, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y

A new dosing paradigm: high-dose, short-course fluoroquinolone therapy for community-acquired pneumonia.

The goals of optimal antimicrobial therapy are to treat infection effectively, to improve the clinical condition of the patient, and to prevent the emergence of resistant bacterial strains. For ideal drug usage the World Health Organization…

Tags: 2003, Clinical cornerstone, Community-Acquired Infections/*drug therapy, Department of Internal Medicine, File Thomas M Jr, Fluoroquinolones/*administration & dosage/pharmacology/therapeutic use, Humans, NEOMED College of Medicine, Ofloxacin/administration & dosage/pharmacology/therapeutic use, Pneumococcal/*drug therapy, Pneumonia, Safety, Time Factors, Treatment Outcome

Physician assessment of patient motivation: influence on disposition for follow-up care.

This study of 3,318 outpatient visits evaluated the influence of the physician-assessed level of patient motivation on the level of physician involvement in follow-up care. Data collected included patient demographics, health risk factors,…

Olfactory bulb norepinephrine depletion abolishes vasopressin and oxytocin preservation of social recognition responses in rats.

Male rats were implanted bilaterally with cannulae directed at the olfactory bulbs and infused with either vehicle or 6-OHDA to selectively deplete norepinephrine concentrations at this site. At 5-7 days following this treatment, these animals…

Tags: *Social Behavior, 1998, Animals, Arginine Vasopressin/administration & dosage/*pharmacology, Dluzen D E, Infusions, Landgraf R, Male, Muraoka S, Neuroscience letters, Norepinephrine/*physiology, Olfactory Bulb/drug effects/*physiology, Oxidopamine/administration & dosage/pharmacology, Oxytocin/administration & dosage/*pharmacology, Parenteral, Rats, Time Factors, Wistar

Drug-drug discrimination: stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum.

Ten male N/Nih rats were trained to discriminate between the interoceptive cues produced by the purportedly dopaminergically-mediated drug d-amphetamine at 0.4 mg/kg intraperitoneally administered 20 min prior to training and those produced by the…

Awake aortic aneurysm repair in patients with severe pulmonary disease.

BACKGROUND: We report the use of retroperitoneal aortic aneurysm repair utilizing exclusive regional anesthesia (no intubation or inhalation anesthetic) in high pulmonary risk patients. METHODS: Six patients were retrospectively reviewed. Pulmonary…

Tags: *Consciousness, 1999, Abdominal/*surgery, Administration, Aged, Albuterol/administration & dosage/therapeutic use, American journal of surgery, Anesthesia, Aortic Aneurysm, Blood Loss, Bronchodilator Agents/administration & dosage/therapeutic use, Critical Care, Epidural, Forced Expiratory Volume/physiology, General, Hirko M K, Home Care Services, Hospitalization, Humans, Hypnotics and Sedatives/administration & dosage, Iliac Aneurysm/*surgery, Inhalation, Intravenous, Koler A J, Labat G C, Length of Stay, Lung Diseases/*complications/drug therapy/therapy, McGregor W E, Oxygen Inhalation Therapy, Perni V, Retroperitoneal Space, Retrospective Studies, Risk Factors, Rubin J R, Safety, Steroids/administration & dosage/therapeutic use, Surgical, Theophylline/administration & dosage/therapeutic use, Time Factors, Vital Capacity/physiology

Expression of pituitary adenylate cyclase activating peptide in the uterine cervix, lumbosacral dorsal root ganglia and spinal cord of rats during pregnancy.

The uterine cervix is highly innervated by the sensory nerves containing neuropeptides which change during pregnancy and are regulated, in part, by estrogen. These neuropeptides act as transmitters both in the spinal cord and cervix. The present…

Relationships among gender, age, time, and temperature in methamphetamine-induced striatal dopaminergic neurotoxicity.

A neurotoxic regimen of methamphetamine (MA-40 mg/kg ip) administered at 0 (control-MA vehicle), 0.5 and 72 h prior to determinations of striatal dopamine (DA) and DOPAC (3,4-dihydroxyphenylacetic acid)/DA ratios were compared among juvenile and…

Early development of intrinsic and synaptic properties of chicken nucleus laminaris neurons.

Onset of auditory brainstem responses in chickens takes place at about embryonic day 11/12 (E11/12). We investigated early development of neuronal properties of chicken nucleus laminaris neurons, the third-order auditory neurons critically involved…

Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.

Inflammation arising from central and/or peripheral sources contributes to the pathogenesis of multiple neurodegenerative diseases including Parkinson's disease (PD). Emerging data suggest that differential activation of glia could lead to the…

Safe Readministration of Intravenous Thrombolysis in Recurrent Basilar Thrombosis.

We report a patient who had recurrence of stroke in the basilar artery territory because of repeat thrombosis, and was administered intravenous recombinant tissue plasminogen activator (IV-rtPA) twice within a span of 3 weeks without any adverse…

Tags: 2018, Aged, Basilar Artery, Basilar Artery – Drug Effects, Basilar Artery – Physiopathology, Basilar Artery/diagnostic imaging/*drug effects/physiopathology, Cerebral Angiography – Methods, Cerebral Angiography/methods, Computed Tomography Angiography, Department of Internal Medicine, Drug Administration Schedule, Fibrinolytic Agents – Administration and Dosage, Fibrinolytic Agents – Adverse Effects, Fibrinolytic Agents/*administration & dosage/adverse effects, Humans, Infusions, Intracranial Thrombosis, Intracranial Thrombosis – Drug Therapy, Intracranial Thrombosis – Physiopathology, Intracranial Thrombosis/diagnostic imaging/*drug therapy/physiopathology, Intravenous, Itrat Ahmed, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Khan Alina, Magnetic Resonance Imaging, Male, medication safety, NEOMED College of Medicine, Recombinant Proteins – Administration and Dosage, Recombinant Proteins/administration & dosage, Recurrence, recurrent stroke, Repeat Procedures, Retreatment, thrombolysis, Thrombolytic Therapy – Adverse Effects, Thrombolytic Therapy – Methods, Thrombolytic Therapy/adverse effects/*methods, Thrombosis, Time Factors, Tissue Plasminogen Activator – Administration and Dosage, Tissue Plasminogen Activator – Adverse Effects, Tissue Plasminogen Activator/*administration & dosage/adverse effects, Treatment Outcome, Treatment Outcomes

Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?

Reversal of antiplatelet therapy with platelet transfusion in traumatic intracranial hemorrhage remains controversial. Several studies have examined this topic but few have investigated whether the timing of transfusion affects outcomes. Patients…

An improved approach to separating startle data from noise.

BACKGROUND: The acoustic startle reflex (ASR) is a rapid, involuntary movement to sound, found in many species. The ASR can be modulated by external stimuli and internal state, making it a useful tool in many disciplines. ASR data collection and…

The effect of freezing and extraction upon striatal dopaminergic function.

Determinations of striatal dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) concentrations were compared under conditions where tissue was either frozen followed by extraction (FE) or extracted followed by freezing (EF). In Experiment 1,…

Tags: *Freezing, 2011, 3, 4-Dihydroxyphenylacetic Acid/metabolism, Analysis of Variance, Animals, Chemical Fractionation/methods, Corpus Striatum/*metabolism, Cryopreservation/methods, Dluzen Dean E, Dopamine/*metabolism, Journal of neuroscience methods, Male, Mice, Time Factors

Macrolide therapy for community-acquired pneumonia due to atypical pathogens: outcome assessment at an early time point.

BACKGROUND: Therapy directed against atypical pathogens in patients with community-acquired pneumonia (CAP) is often recommended. This post-hoc analysis evaluated the effect of addition of a macrolide to ceftaroline fosamil or ceftriaxone treatment…

Tags: 2017, 80 and over, Adult, Aged, Anti-Bacterial Agents/adverse effects/*therapeutic use, Atypical pathogen, Bacterial/*drug therapy, Ceftaroline fosamil, Ceftriaxone/adverse effects/*therapeutic use, Cephalosporins/adverse effects/*therapeutic use, Chlamydial Pneumonia, Chlamydophila pneumoniae, Clinical Trials, Combination/adverse effects/methods, Community-Acquired Infections/*drug therapy, Community-acquired pneumonia, Department of Internal Medicine, Double-Blind Method, Drug Therapy, Eckburg Paul B, Female, File Thomas M Jr, Friedland H David, Humans, International journal of antimicrobial agents, Legionella pneumophila, Llorens Lily, Macrolide, Macrolides/adverse effects/*therapeutic use, Male, Middle Aged, Mycoplasma, Mycoplasma pneumoniae, NEOMED College of Medicine, Phase III as Topic, Pneumonia, Randomized Controlled Trials as Topic, Talbot George H, Time Factors, Treatment Outcome

Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma.

Glaucoma challenges the survival of retinal ganglion cell axons in the optic nerve through processes dependent on both aging and ocular pressure. Relevant stressors likely include complex interplay between axons and astrocytes, both in the retina and…

Pregnancy zone protein is a carrier and modulator of placental protein-14 in

A successful pregnancy can only occur when the maternal immune system fails to attack the allogeneic fetus. Two plasma proteins with described immunoregulatory activities, pregnancy zone protein (PZP) and placental protein-14 (PP14; also known as…

Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-kappaB/HIF-1alpha pathway.

Due to the existence of cancer stem cells (CSCs), persistence and relapse of human hepatocellular carcinoma (HCC) are common after treatment with existing anti-cancer therapies. Emerging evidence indicates that lipopolysaccharide (LPS) plays a…

Tags: *Cancer stem cells, *Lipopolysaccharide, *Plasticity, *Stemness maintenance, *Tumor microenvironment, 2016, AC133 Antigen/genetics/*metabolism, alpha Subunit/genetics/*metabolism, Animals, Antineoplastic Agents – Pharmacodynamics, Antineoplastic Agents/pharmacology, Body Weights and Measures, Cancer letters, Carcinoma, Cell Line, Cell Movement – Drug Effects, Cell Movement/drug effects, Cell Physiology, Cell Physiology – Drug Effects, Cell Proliferation/drug effects, Department of Integrative Medical Sciences, Drug Resistance, Gene Expression Regulation, Genes, Genetic Techniques, Han Zhi-Peng, Hepatocellular, Hepatocellular – Drug Therapy, Hepatocellular – Metabolism, Hepatocellular – Pathology, Hepatocellular/drug therapy/genetics/*metabolism/pathology, Humans, Hypoxia-Inducible Factor 1, Inbred BALB C, Jing Ying-Ying, Lai Fo-Bao, Li Rong, Li Xiao-Yong, Lipopolysaccharides – Pharmacodynamics, Lipopolysaccharides/*pharmacology, Liu Jing-Feng, Liu Wen-Ting, Liver Neoplasms, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms/drug therapy/genetics/*metabolism/pathology, Male, Mice, NEOMED College of Medicine, Neoplasm, Neoplasm Invasiveness, Neoplastic, Neoplastic Stem Cells/*drug effects/metabolism/pathology, NF-kappa B – Metabolism, NF-kappa B/*metabolism, Nude, Pan Xiao-Rong, Phenotype, Proteins, Proteins – Metabolism, RNA Interference, Shi Rong-Yu, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Stem Cells – Drug Effects, Stem Cells – Metabolism, Stem Cells – Pathology, Time Factors, Transfection, Tumor Burden, Tumor Microenvironment, Wei Li-Xin, Wu Meng-Chao, Yang Xue, Yu Guo-Feng, Zeng Jian-Xing, Zhang Hang-Jie, Zhang Ping, Zhao Qiu-Dong

Keloid treatment: is there a role for acellular human dermis (Alloderm)?

BACKGROUND: Keloid management is faced with high recurrence rates. Keloid fibroblasts lack the normal negative feedback mechanism resulting in an exuberant scar formation. Alloderm doesn't undergo the same proliferative process as keloidal scar…

Temperature-sensitive Medications in Interfacility Transport: The Ice Pack Myth.

INTRODUCTION: Critical Care Transport teams use various strategies to maintain temperature sensitive drugs and equipment at optimal temperature. The purpose of this study was to examine the effectiveness of current passive refrigeration of…

Outcomes of non-STEMI patients transported by emergency medical services vs private vehicle.

BACKGROUND: Non-ST-segment elevation myocardial infarctions (NSTEMIs) are more common but less studied than ST-segment elevation myocardial infarctions (STEMIs) treated by emergency medical services (EMS). OBJECTIVE: The purpose of this study was to…

Tags: *Electrocardiography, 2016, 80 and over, Adult, Age Distribution, Aged, Baughman Kristin, Bhalla Mary Colleen, Comparative Studies, Demography, Department of Family & Community Medicine, Dials Sarah, Electrocardiography, Emergency Medical Services – Methods, Emergency Medical Services – Statistics and Numerical Data, Emergency Medical Services/methods/*statistics & numerical data, Evaluation Research, Female, Frey Jennifer, Hospital Mortality, Human, Humans, Length of Stay – Statistics and Numerical Data, Length of Stay/statistics & numerical data, Male, Medical Records – Statistics and Numerical Data, Medical Records/statistics & numerical data, Middle Age, Middle Aged, Multicenter Studies, Myocardial Infarction – Diagnosis, Myocardial Infarction – Mortality, Myocardial Infarction – Therapy, Myocardial Infarction/diagnosis/*mortality/therapy, NEOMED College of Medicine, Ohio, Ohio/epidemiology, Outcome Assessment – Statistics and Numerical Data, Outcome Assessment (Health Care)/*statistics & numerical data, Retrospective Design, Retrospective Studies, Severity of Illness Index, Severity of Illness Indices, The American journal of emergency medicine, Time Factors, Transportation of Patients – Methods, Transportation of Patients – Statistics and Numerical Data, Transportation of Patients/*methods/*statistics & numerical data, Trauma Centers – Statistics and Numerical Data, Trauma Centers/statistics & numerical data, Validation Studies

A comparison of implanted cardioverter/defibrillator interrogation protocol effectiveness between 2 patients in the ED.

Ethanol-produced interoceptive stimuli are time dependent in selectively bred HAS and LAS rats.

Fourteenth generation high alcohol-sensitive (HAS) and low alcohol-sensitive (LAS) rats were trained to discriminate the effects of 600 mg/kg intraperitoneally administered ethanol from its vehicle at 6 and 30 min postadministration. Each of the…

Tags: *Discrimination Learning, 1992, Alcohol (Fayetteville, N.Y.), Animals, Dose-Response Relationship, Drug, Drug Tolerance, Ethanol/administration & dosage/*pharmacology, Male, Rats, Schechter M D, Time Factors

N-methyl-D-aspartate receptor-independent long-term potentiation in area CA1 of rat hippocampus: input-specific induction and preclusion in a non-tetanized pathway.

We previously reported that an N-methyl-D-aspartate receptor-independent component of long-term potentiation with an apparent delayed onset can be induced in area CA1 of the hippocampus. Here we show that some but not all of this delay in onset can…

Tags: 1992, 2-Amino-5-phosphonovalerate/*pharmacology, Animals, Electron, Evoked Potentials/drug effects, Grover L M, Hippocampus/*physiology, In Vitro Techniques, Microscopy, N-Methyl-D-Aspartate/*physiology, N-Methylaspartate/*pharmacology, Neuroscience, Pyramidal Tracts/drug effects/*physiology, Rats, Receptors, Teyler T J, Time Factors

Expression of alpha-cardiac myosin heavy chain in normal and denervated rat muscle spindles.

Whether any fibers in rat hindlimb muscles express alpha-cardiac myosin heavy chain (MHC) is uncertain. Expression of alpha-cardiac MHC mRNA and the polypeptide for which it codes were examined in control and denervated rat muscle spindles using in…

Tags: 1995, Animals, Denervation, In Situ Hybridization, McWhorter D L, Messenger/metabolism, Muscle Spindles/*metabolism/physiology, Myocardium/*metabolism, Myosin Heavy Chains/*metabolism, Neuroscience letters, Rats, RNA, Signs S A, Sprague-Dawley, Time Factors, Walro J M, Wang J

Serotonergic involvement in the regulation of prolactin and vasoactive intestinal peptide mRNA expression in the rat anterior pituitary.

These studies examined the contribution of serotonin (5-HT) to the control of prolactin (PRL) and vasoactive intestinal peptide (VIP) messenger RNA expression in rat anterior pituitary. Daily injection of rats with the biosynthetic precursor to…

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