1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.spinee.2021.03.007" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.spinee.2021.03.007</a> ISSN 1878-1632 1529-9430 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1016/j.spinee.2021.03.007" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1016/j.spinee.2021.03.007</a> <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Update Year & Number April 2021 List NEOMED College NEOMED College of Medicine Student NEOMED Department NEOMED Student Publications Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Prospective comparison of the accuracy of the New England spinal metastasis score (NESMS) to legacy scoring systems in prognosticating outcomes following treatment of spinal metastases. Publisher An entity responsible for making the resource available The Spine Journal Date A point or period of time associated with an event in the lifecycle of the resource 2021 2021-03-16 Subject The topic of the resource Decision-making; NESMS; Prognostic score; SINS; Spinal metastases; Survival; Tokuhashi; Tomita Creator An entity primarily responsible for making the resource Schoenfeld AJ; Ferrone ML; Blucher JA; Agaronnik N; Nguyen L; Tobert Daniel G; Balboni TA; Schwab JH; Shin JH; Sciubba DM; Harris MB Description An account of the resource BACKGROUND CONTEXT: We developed the New England Spinal Metastasis Score (NESMS) as a simple, informative, scoring scheme that could be applied to both operative and non-operative patients. The performance of the NESMS to other legacy scoring systems has not previously been compared using appropriately powered, prospectively collected, longitudinal data. PURPOSE: To compare the predictive capacity of the NESMS to the Tokuhashi, Tomita and Spinal Instability Neoplastic Score (SINS) in a prospective cohort, where all scores were assigned at the time of baseline enrollment. PATIENT SAMPLE: We enrolled 202 patients with spinal metastases who met inclusion criteria between 2017-2019. OUTCOME MEASURES: One-year survival (primary); 3-month mortality and ambulatory function at 3- and 6-months were considered secondarily. METHODS: All prognostic scores were assigned based on enrollment data, which was also assigned as time-zero. Patients were followed until death or survival at 365 days after enrollment. Survival was assessed using Kaplan-Meier curves and score performance was determined via logistic regression testing and observed to expected plots. The discriminative capacity (c-statistic) of the scoring measures were compared via the z-score. RESULTS: When comparing the discriminative capacity of the predictive scores, the NESMS had the highest c-statistic (0.79), followed by the Tomita (0.69), the Tokuhashi (0.67) and the SINS (0.54). The discriminative capacity of the NESMS was significantly greater (p-value range: 0.02 to <0.001) than any of the other predictive tools. The NESMS was also able to inform independent ambulatory function at 3- and 6-months, a function that was only uniformly replicated by the Tokuhashi score. CONCLUSIONS: The results of this prospective validation study indicate that the NESMS was able to differentiate survival to a significantly higher degree than the Tokuhashi, Tomita and SINS. We believe that these findings endorse the utilization of the NESMS as a prognostic tool capable of informing care for patients with spinal metastases. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.spinee.2021.03.007" target="_blank" rel="noreferrer noopener">10.1016/j.spinee.2021.03.007</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Format The file format, physical medium, or dimensions of the resource journalArticle 2021 Agaronnik N April 2021 List Balboni TA Blucher JA Decision-making Ferrone ML Harris MB journalArticle NEOMED College of Medicine Student NESMS Nguyen L Prognostic score Schoenfeld AJ Schwab JH Sciubba DM Shin JH SINS Spinal metastases Survival The Spine Journal Tobert Daniel G Tokuhashi Tomita