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Text
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URL Address
<a href="http://doi.org/10.1155/2014/502093" target="_blank" rel="noreferrer noopener">http://doi.org/10.1155/2014/502093</a>
Pages
502093–502093
Volume
2014
Dublin Core
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Title
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Role of the adjacent stroma cells in prostate cancer development and progression: synergy between TGF-beta and IGF signaling.
Publisher
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BioMed research international
Date
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2014
1905-07
Subject
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Androgens/metabolism; Animals; Disease Progression; Epithelial Cells/cytology; Estrogen/metabolism; Estrogens/metabolism; Humans; Male; Mice; Prostate/metabolism; Prostatic Neoplasms/*metabolism; Receptors; Signal Transduction; Somatomedins/*metabolism; Stromal Cells/*cytology; Transforming Growth Factor beta/*metabolism
Creator
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Lee Chung; Jia Zhenyu; Rahmatpanah Farah; Zhang Qiang; Zi Xiaolin; McClelland Michael; Mercola Dan
Description
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This review postulates the role of transforming growth factor-beta (TGF-beta) and insulin-like growth factor (IGF-I/IGF-II) signaling in stromal cells during prostate carcinogenesis and progression. It is known that stromal cells have a reciprocal relationship to the adjacent epithelial cells in the maintenance of structural and functional integrity of the prostate. An interaction between
Identifier
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<a href="http://doi.org/10.1155/2014/502093" target="_blank" rel="noreferrer noopener">10.1155/2014/502093</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2014
Androgens/metabolism
Animals
BioMed research international
Disease Progression
Epithelial Cells/cytology
Estrogen/metabolism
Estrogens/metabolism
Humans
Jia Zhenyu
Lee Chung
Male
McClelland Michael
Mercola Dan
Mice
Prostate/metabolism
Prostatic Neoplasms/*metabolism
Rahmatpanah Farah
Receptors
Signal Transduction
Somatomedins/*metabolism
Stromal Cells/*cytology
Transforming Growth Factor beta/*metabolism
Zhang Qiang
Zi Xiaolin