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Text
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URL Address
<a href="http://doi.org/10.1016/j.bjps.2009.07.032" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.bjps.2009.07.032</a>
Pages
1344–1348
Issue
8
Volume
63
Dublin Core
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Title
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Keloid treatment: is there a role for acellular human dermis (Alloderm)?
Publisher
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Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Date
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2010
2010-08
Subject
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Artificial; Child; Collagen/*therapeutic use; Female; Follow-Up Studies; Glucocorticoids/administration & dosage; Humans; Injections; Intralesional; Keloid/*therapy; Male; Middle Aged; Reconstructive Surgical Procedures/*methods; Retrospective Studies; Skin; Time Factors; Treatment Outcome; Triamcinolone Acetonide/administration & dosage; Young Adult
Creator
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Patel Nima P; Cervino A Lawrence
Description
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BACKGROUND: Keloid management is faced with high recurrence rates. Keloid fibroblasts lack the normal negative feedback mechanism resulting in an exuberant scar formation. Alloderm doesn't undergo the same proliferative process as keloidal scar dermis. OBJECTIVE: To evaluate Alloderm as a treatment modality for keloids METHODS: A retrospective chart review of six patients with a total of eight large recurrent keloids was performed. Patients were treated with excision of the keloid followed by placement of Alloderm. Each patient was evaluated for recurrence and complications. RESULTS: During follow-up ranging from 1 month to 4(1/2) years there were 0% recurrences. Two out of 8 (25%) had residual induration. one of the two patients with residual induration, required an intralesional injection of kenalog at 6 months post-op. CONCLUSION: Our results from this small study show that with the use of Alloderm after keloid excision, recurrence is low. Further study is warranted.
Identifier
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<a href="http://doi.org/10.1016/j.bjps.2009.07.032" target="_blank" rel="noreferrer noopener">10.1016/j.bjps.2009.07.032</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2010
Artificial
Cervino A Lawrence
Child
Collagen/*therapeutic use
Female
Follow-Up Studies
Glucocorticoids/administration & dosage
Humans
Injections
Intralesional
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Keloid/*therapy
Male
Middle Aged
Patel Nima P
Reconstructive Surgical Procedures/*methods
Retrospective Studies
Skin
Time Factors
Treatment Outcome
Triamcinolone Acetonide/administration & dosage
Young Adult