Vancomycin Combined with Piperacillin-Tazobactam Increases the Risk for Acute Kidney Injury.
Antibiotics; Drug Interactions; Kidney Failure; Drug Therapy; Vancomycin; Ampicillin – Therapeutic Use; Vancomycin – Therapeutic Use; Acute – Risk Factors; Cefepime Hydrochloride – Therapeutic Use; Combination – Adverse Effects; Lactam – Adverse Effects
The article comments on the retrospective cohort study "Risk of acute kidney injury in patients on concomitant vancomycin and piperacillin-tazobactam compared to those on vancomycin and cefepime" by B. Navalkele and colleagues. The study found that vancomycin paired with piperacillin-tazobactam increases the risk of acute kidney injury. It recommends clinicians to weigh the risks and benefits of vancomycin and piperacillin-tazobactam given the onset of acute kidney injury.
Watkins Richard R
Infectious Disease Alert
2017
2017-03
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Fidaxomicin More Effective than Vancomycin for Clostridium difficile Infection in Cancer Patients?
Cancer Patients; Randomized Controlled Trials; Double-Blind Studies; Vancomycin – Therapeutic Use; Clostridium Infections – Drug Therapy; Confidence Intervals – Utilization; Odds Ratio – Utilization; Fidaxomicin – Therapeutic Use; Recurrence – Prevention and Control
Watkins Richard R
Infectious Disease Alert
2013
2013-12
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Fecal Transplant vs. Oral Vancomycin Taper for Recurrent Clostridium difficile Infection.
Recurrence; Costs and Cost Analysis; Enema; Administration; Oral; Treatment Outcomes; Randomized Controlled Trials; Cost Benefit Analysis; Microbiota; Transplant Donors; Vancomycin – Therapeutic Use; Clostridium Infections – Drug Therapy; Clostridium Infections – Prevention and Control; Clostridium Infections – Therapy; Feces – Transplantation; Recurrence – Therapy; Vancomycin – Administration and Dosage; Vancomycin – Economics
In a small randomized, controlled trial that compared fecal microbiota transplant (FMT) administered by enema to a six-week oral vancomycin taper, FMT was not more effective for patients with recurrent Clostridium difficile infection.
Watkins Richard R
Infectious Disease Alert
2017
2017-01
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Cefazolin Leads to Better Outcomes for Methicillin-susceptible Staphylococcus aureus Bacteremia Than Nafcillin or Oxacillin.
Treatment Outcomes; Staphylococcal Infections – Drug Therapy; Treatment Outcomes – Evaluation; Bacteremia – Drug Therapy; Cefazolin – Therapeutic Use; Drug Therapy – Evaluation; Nafcillin – Therapeutic Use; Oxacillin – Therapeutic Use; Vancomycin – Therapeutic Use
A retrospective study that included patients from 119 Veterans Affairs hospitals found lower mortality and a similar recurrence rate for methicillin-susceptible Staphylococcus aureus bacteremia treated with cefazolin compared to nafcillin and oxacillin.
Watkins Richard R
Infectious Disease Alert
2017
2017-08
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).