1
40
2
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.1993.265.4.H1184" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.1993.265.4.H1184</a>
Pages
H1184–1188
Issue
4
Volume
265
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine.
Publisher
An entity responsible for making the resource available
The American journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-10
Subject
The topic of the resource
*Physical Exertion; Animals; Arginine/analogs & derivatives/pharmacology; Blood Flow Velocity; Blood Pressure/drug effects; Blood Vessels/*drug effects; Dose-Response Relationship; Drug; Female; Heart Rate/drug effects; Iliac Artery/drug effects/physiology; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide/antagonists & inhibitors/*physiology; Phenylephrine/*pharmacology; Rats; Sprague-Dawley; Time Factors; Vasoconstriction/drug effects/physiology
Creator
An entity primarily responsible for making the resource
Patil R D; DiCarlo S E; Collins H L
Description
An account of the resource
The influence of the release of endothelium-derived nitric oxide (NO) on the vasoconstrictor response to phenylephrine (PE) was evaluated before and after a single bout of dynamic exercise. Each rat ran on a motor-driven treadmill at
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.1993.265.4.H1184" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.1993.265.4.H1184</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Physical Exertion
1993
Animals
Arginine/analogs & derivatives/pharmacology
Blood Flow Velocity
Blood Pressure/drug effects
Blood Vessels/*drug effects
Collins H L
DiCarlo S E
Dose-Response Relationship
Drug
Female
Heart Rate/drug effects
Iliac Artery/drug effects/physiology
Male
NG-Nitroarginine Methyl Ester
Nitric Oxide/antagonists & inhibitors/*physiology
Patil R D
Phenylephrine/*pharmacology
Rats
Sprague-Dawley
The American journal of physiology
Time Factors
Vasoconstriction/drug effects/physiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/jappl.1998.84.2.618" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/jappl.1998.84.2.618</a>
Pages
618–623
Issue
2
Volume
84
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effect of neuropeptide Y on hemodynamics of the rabbit lung.
Publisher
An entity responsible for making the resource available
Journal of applied physiology (Bethesda, Md. : 1985)
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1998-02
Subject
The topic of the resource
Animals; Cisterna Magna; Hemodynamics/*physiology; In Vitro Techniques; Injections; Neuropeptide Y/blood/pharmacology/*physiology; Norepinephrine/pharmacology; Perfusion; Pulmonary Circulation/drug effects/*physiology; Rabbits; Sympathetic Nervous System/drug effects/physiology; Vascular Resistance/drug effects/physiology; Vasoconstriction/drug effects/physiology; Vasoconstrictor Agents/pharmacology; Veratrine/administration & dosage/pharmacology
Creator
An entity primarily responsible for making the resource
Lang S A; Maron M B
Description
An account of the resource
We evaluated the effect of neuropeptide Y (NPY) on the hemodynamics of the isolated rabbit lung perfused at constant flow and outflow pressure. Doses of 10(-8) and 10(-7) M NPY increased pulmonary arterial pressure (Ppa) from 11.5 +/- 1.0 (SE) mmHg to, respectively, 16.4 +/- 1.5 and 26.0 +/- 3.8 mmHg (P \textless 0.05, n = 5 mmHg lungs), with 78 +/- 4% of the increase at 10(-7) M resulting from an increased arterial resistance. At the latter dose, pulmonary capillary pressure increased from 5.8 +/- 0.9 to 9.4 +/- 1.0 mmHg (P \textless 0.05). When administered in the presence of norepinephrine, 10(-8) and 10(-7) M NPY (n = 6) produced extreme increases in Ppa to 66.1 +/- 20.5 and 114.7 +/- 25.5 mmHg, respectively, that were due primarily to an increased arterial resistance. To determine the significance of circulating NPY as a pulmonary vasoactive agent, we measured plasma NPY-like immunoreactivity in anesthetized rabbits after massively activating the sympathetic nervous system with veratrine. NPY-like immunoreactivity increased from 74 +/- 10 to 111 +/- 10 (SE) pM (P \textless 0.05). Thus, although NPY is a potent vasoconstrictor in the rabbit lung, it is not likely that plasma NPY concentrations rise sufficiently, even after massive sympathetic nervous system activation, to produce pulmonary vasoconstriction in the intact rabbit.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/jappl.1998.84.2.618" target="_blank" rel="noreferrer noopener">10.1152/jappl.1998.84.2.618</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1998
Animals
Cisterna Magna
Hemodynamics/*physiology
In Vitro Techniques
Injections
Journal of applied physiology (Bethesda, Md. : 1985)
Lang S A
Maron M B
Neuropeptide Y/blood/pharmacology/*physiology
Norepinephrine/pharmacology
Perfusion
Pulmonary Circulation/drug effects/*physiology
Rabbits
Sympathetic Nervous System/drug effects/physiology
Vascular Resistance/drug effects/physiology
Vasoconstriction/drug effects/physiology
Vasoconstrictor Agents/pharmacology
Veratrine/administration & dosage/pharmacology