1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.amjcard.2009.06.042" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.amjcard.2009.06.042</a> Pages 1251–1255 Issue 9 Volume 104 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Effects of bariatric surgery on inflammatory, functional and structural markers of coronary atherosclerosis. Publisher An entity responsible for making the resource available The American journal of cardiology Date A point or period of time associated with an event in the lifecycle of the resource 2009 2009-11 Subject The topic of the resource *Gastric Bypass; Adult; Biological Markers – Blood; Biomarkers/blood; Blood Flow Velocity – Physiology; Blood Flow Velocity/physiology; Blood Vessels – Pathology; Body Mass Index; Brachial Artery – Ultrasonography; Brachial Artery/diagnostic imaging; C-Reactive Protein – Analysis; C-Reactive Protein/analysis; Carotid Arteries – Pathology; Carotid Arteries/pathology; Cholesterol – Blood; Cholesterol/blood; Coronary Arteriosclerosis – Blood; Coronary Arteriosclerosis – Pathology; Coronary Arteriosclerosis – Physiopathology; Coronary Artery Disease/*blood/pathology/*physiopathology; Female; Follow-Up Studies; Gastric Bypass; Human; Humans; Male; Muscle; Prospective Studies; Smooth – Pathology; Triglycerides – Blood; Triglycerides/blood; Tunica Intima/pathology; Tunica Media/pathology; Ultrasonography; Vasodilation – Physiology; Vasodilation/physiology Creator An entity primarily responsible for making the resource Habib Phillip; Scrocco John David; Terek Megan; Vanek Vincent; Mikolich J Ronald Description An account of the resource This study was designed to assess the effects of bariatric weight loss surgery on structural, functional, and inflammatory markers of coronary atherosclerosis. Obesity is a worldwide epidemic and an independent risk factor for coronary atherosclerosis. It remains unclear whether surgically induced weight loss reduces cardiovascular risk. This prospective study enrolled 50 consecutive subjects with morbid obesity who underwent Roux-en-Y gastric bypass surgery (GBS) after failed attempts at medical weight loss. Subjects were recruited through a comprehensive weight loss center affiliated with an academic tertiary care hospital. All subjects had body mass indexes \textgreater or =40 kg/m(2) or body mass indexes of 35 to 40 kg/m(2) with \textgreater or =2 co-morbid obesity-related conditions. Markers of coronary atherosclerosis, including brachial artery flow-mediated dilation, carotid intima-media thickness, and high-sensitivity C-reactive protein, were measured before GBS and 6, 12, and 24 months after GBS. There were statistically significant improvements in all measured markers of coronary atherosclerosis after GBS. The mean body mass index decreased from 47 to 29.5 kg/m(2) at 24 months (p \textless0.001), the mean carotid intima-media thickness regressed from 0.84 to 0.50 mm at 24 months (p \textless0.001), mean flow-mediated dilation improved from 6.0% to 14.9% at 24 months (p \textless0.05), and mean high-sensitivity C-reactive protein decreased from 1.23 to 0.65 mg/dl at 6 months (p \textless0.001) and to 0.35 mg/dl at 24 months (p \textless0.001). In conclusion, GBS results in significant improvements in inflammatory, structural, and functional markers of coronary atherosclerosis. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.amjcard.2009.06.042" target="_blank" rel="noreferrer noopener">10.1016/j.amjcard.2009.06.042</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). *Gastric Bypass 2009 Adult Biological Markers – Blood Biomarkers/blood Blood Flow Velocity – Physiology Blood Flow Velocity/physiology Blood Vessels – Pathology Body Mass Index Brachial Artery – Ultrasonography Brachial Artery/diagnostic imaging C-Reactive Protein – Analysis C-Reactive Protein/analysis Carotid Arteries – Pathology Carotid Arteries/pathology Cholesterol – Blood Cholesterol/blood Coronary Arteriosclerosis – Blood Coronary Arteriosclerosis – Pathology Coronary Arteriosclerosis – Physiopathology Coronary Artery Disease/*blood/pathology/*physiopathology Department of Internal Medicine Female Follow-Up Studies Gastric Bypass Habib Phillip Human Humans Male Mikolich J Ronald Muscle NEOMED College of Medicine Prospective Studies Scrocco John David Smooth – Pathology Terek Megan The American journal of cardiology Triglycerides – Blood Triglycerides/blood Tunica Intima/pathology Tunica Media/pathology Ultrasonography Vanek Vincent Vasodilation – Physiology Vasodilation/physiology