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                <text>Trends in demographics and markers of injury severity in traumatic cervical spinal cord injury.</text>
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                <text>cervical; epidemiology; MRI; spinal cord injury; trauma</text>
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                <text>Aarabi B; Albrecht JS; Simard JM; Chryssikos T; Schwartzbauer G; Sansur CA; Crandall K; Gertner M; Howie B; Wessell A; Cannarsa G; Caffes N; Oliver J; Shanmuganathan K; Olexa J; Lomangino CD; Scarboro M</text>
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                <text>Over the past four decades, there have been progressive changes in the epidemiology of traumatic spinal cord injury (tSCI). We assessed trends in demographic and  injury-related variables in traumatic cervical spinal cord injury (tCSCI) patients  over an 18-year period at a single Level I trauma center. We included all magnetic  resonance imaging-confirmed tCSCI patients ≥15 years of age for years 2001-2018.  Among 1420 patients, 78.3% were male with a mean age 51.5 years. Etiology included  falls (46.9%), motor vehicle collisions (MVCs; 34.2%), and sports injuries (10.9%).  Median American Spinal Injury Association (ASIA) Motor Score (AMS) was 44, complete  tCSCI was noted in 29.6% of patients, fracture dislocations were noted in 44.7%, and  median intramedullary lesion length (IMLL) was 30.8 mm (complete injuries 56.3 mm  and incomplete injuries 27.4 mm). Over the study period, mean age and proportion of  falls increased (p &lt; 0.001) whereas proportion attributable to MVCs and sports  injuries decreased (p &lt; 0.001). Incomplete injuries, AMS, and the proportion of  patients with no fracture dislocations increased whereas complete injuries decreased  significantly. IMLL declined (p = 0.17) and proportion with hematomyelia did not  change significantly. In adjusted regression models, increase in age and decreases  in prevalence of MVC mechanism and complete injuries over time remained  statistically significant. Changes in demographic and injury-related characteristics  of tCSCI patients over time may help explain the observed improvement in outcomes.  Further, improved clinical outcomes and drop in IMLL may reflect improvements in  initial risk assessment and pre-hospital management, advances in healthcare  delivery, and preventive measures including public education.</text>
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                <text>&lt;a href="http://doi.org/10.1089/neu.2020.7415" target="_blank" rel="noreferrer noopener"&gt;10.1089/neu.2020.7415&lt;/a&gt;</text>
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