1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="https://iovs.arvojournals.org/article.aspx?articleid=2743996" target="_blank" rel="noreferrer noopener">https://iovs.arvojournals.org/article.aspx?articleid=2743996</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Issue
9
Volume
60
ISSN
0146-0404
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Sight for Kids: Improving the Vision of Children in an At-Risk Population
Publisher
An entity responsible for making the resource available
Investigative Ophthalmology & Visual Science
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-07
Creator
An entity primarily responsible for making the resource
Yusuf Saidah; Yalamanchili Siri; Parikh Ankur A; Erzurum Sergul
Identifier
An unambiguous reference to the resource within a given context
<a href="https://iovs.arvojournals.org/article.aspx?articleid=2743996" target="_blank" rel="noreferrer noopener">https://iovs.arvojournals.org/article.aspx?articleid=2743996</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2019
Erzurum Sergul
Investigative ophthalmology & visual science
Journal Article
NEOMED College of Medicine
NEOMED College of Medicine Student
NEOMED Student Publications
November 2019 Update
Parikh Ankur A
Yalamanchili Siri
Yusuf Saidah
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="https://iovs.arvojournals.org/article.aspx?articleid=2742298" target="_blank" rel="noreferrer noopener">https://iovs.arvojournals.org/article.aspx?articleid=2742298</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Issue
9
Volume
60
ISSN
0146-0404
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Impact of the Optiwave Refractive Analysis in Post-LASIK Patients Undergoing Cataract Surgery
Publisher
An entity responsible for making the resource available
Investigative Ophthalmology & Visual Science
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-07
Creator
An entity primarily responsible for making the resource
Yalamanchili Siri; Parikh Ankur A; Gemmel David; Erzurum Sergul
Identifier
An unambiguous reference to the resource within a given context
<a href="https://iovs.arvojournals.org/article.aspx?articleid=2742298" target="_blank" rel="noreferrer noopener">https://iovs.arvojournals.org/article.aspx?articleid=2742298</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2019
Department of General Surgery
Erzurum Sergul
Gemmel David
Investigative ophthalmology & visual science
Journal Article
Mercy Health St Elizabeth Youngstown Hospital
NEOMED College of Medicine
NEOMED College of Medicine Student
NEOMED Student Publications
November 2019 Update
Parikh Ankur A
Yalamanchili Siri
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="https://iovs.arvojournals.org/article.aspx?articleid=2745672">https://iovs.arvojournals.org/article.aspx?articleid=2745672</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Issue
9
Volume
60
ISSN
0146-0404
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Dehydrated Extracellular Membranes in the Treatment of Severe Dry Eye
Publisher
An entity responsible for making the resource available
Investigative Ophthalmology & Visual Science
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-07
Creator
An entity primarily responsible for making the resource
Parikh Ankur A; Yalamanchili Siri; Gemmel David; Erzurum Sergul
Identifier
An unambiguous reference to the resource within a given context
<a href="https://iovs.arvojournals.org/article.aspx?articleid=2745672" target="_blank" rel="noreferrer noopener">https://iovs.arvojournals.org/article.aspx?articleid=2745672</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2019
Department of General Surgery
Erzurum Sergul
Gemmel David
Investigative ophthalmology & visual science
Journal Article
Mercy Health St Elizabeth Youngstown Hospital
NEOMED College of Medicine
NEOMED College of Medicine Student
NEOMED Student Publications
November 2019 Update
Parikh Ankur A
Yalamanchili Siri
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1038/srep45279" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/srep45279</a>
Pages
45279–45279
Volume
7
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE(-/-) mice.
Publisher
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Scientific reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-03
Subject
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Animals; Aorta/drug effects/metabolism; Apolipoproteins E/*metabolism; Atherosclerosis/*drug therapy/metabolism; Diabetes Mellitus; Diabetic Angiopathies/drug therapy/metabolism; Experimental/chemically induced/drug therapy/metabolism; Glucose/metabolism; Glycosylation/drug effects; Hyperglycemia/*drug therapy/metabolism; Inbred C57BL; Knockout; Male; Mice; Myocytes; Picolinic Acids/*pharmacology; Smooth Muscle/drug effects; Streptozocin/*pharmacology; Thrombospondin 1/*metabolism; Type 1/chemically induced/*drug therapy/metabolism
Creator
An entity primarily responsible for making the resource
Ganguly Rituparna; Sahu Soumyadip; Ohanyan Vahagn; Haney Rebecca; Chavez Ronaldo J; Shah Shivani; Yalamanchili Siri; Raman Priya
Description
An account of the resource
Increasing evidence suggests thrombospondin-1 (TSP-1), a potent proatherogenic matricellular protein, as a putative link between hyperglycemia and atherosclerotic complications in diabetes. We previously reported that the micronutrient chromium picolinate (CrP), with long-standing cardiovascular benefits, inhibits TSP-1 expression in glucose-stimulated human aortic smooth muscle cells in vitro. Here, we investigated the atheroprotective action of orally administered CrP in type 1 diabetic apolipoprotein E-deficient (ApoE(-/-)) mice and elucidated the role of TSP-1 in this process. CrP decreased lipid burden and neointimal thickness in aortic root lesions of hyperglycemic ApoE(-/-) mice; also, smooth muscle cell (SMC), macrophage and leukocyte abundance was prevented coupled with reduced cell proliferation. Attenuated lesion progression was accompanied with inhibition of hyperglycemia-induced TSP-1 expression and reduced protein O-glycosylation following CrP treatment; also, PCNA and vimentin (SMC synthetic marker) expression were reduced while SM-MHC (SMC contractile marker) levels were increased. To confirm a direct role of TSP-1 in diabetic atherosclerosis, hyperglycemic TSP-1(-/-)/ApoE(-/-) double knockout mice were compared with age-matched hyperglycemic ApoE(-/-) littermates. Lack of TSP-1 prevented lesion formation in hyperglycemic ApoE(-/-) mice, mimicking the atheroprotective phenotype of CrP-treated mice. These results suggest that therapeutic TSP-1 inhibition may have important atheroprotective potential in diabetic vascular disease.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1038/srep45279" target="_blank" rel="noreferrer noopener">10.1038/srep45279</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Animals
Aorta/drug effects/metabolism
Apolipoproteins E/*metabolism
Atherosclerosis/*drug therapy/metabolism
Chavez Ronaldo J
Department of Integrative Medical Sciences
Diabetes Mellitus
Diabetic Angiopathies/drug therapy/metabolism
Experimental/chemically induced/drug therapy/metabolism
Ganguly Rituparna
Glucose/metabolism
Glycosylation/drug effects
Haney Rebecca
Hyperglycemia/*drug therapy/metabolism
Inbred C57BL
Knockout
Male
Mice
Myocytes
NEOMED College of Medicine
NEOMED Student Publications
Ohanyan Vahagn
Picolinic Acids/*pharmacology
Raman Priya
Sahu Soumyadip
Scientific reports
Shah Shivani
Smooth Muscle/drug effects
Streptozocin/*pharmacology
Thrombospondin 1/*metabolism
Type 1/chemically induced/*drug therapy/metabolism
Yalamanchili Siri