1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/ctr.12020" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/ctr.12020</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
121-125
Issue
1
Volume
27
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Reduction Of Lipid-laden Macrophage Index After Laparoscopic Nissen Fundoplication In Cystic Fibrosis Patients After Lung Transplantation
Publisher
An entity responsible for making the resource available
Clinical Transplantation
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013-01
Subject
The topic of the resource
alveolar; aspiration; association; bronchoalveolar lavage fluid; children; chronic rejection; cystic fibrosis; fat-embolism; gastroesophageal reflux; gastroesophageal-reflux disease; laparoscopic; lipid-laden macrophage index; lung; macrophages; marker; Nissen fundoplication; Oil Red O stain; pepsin; pulmonary aspiration; Surgery; transplantation; transplantation
Creator
An entity primarily responsible for making the resource
Hayes D; Kirkby S; McCoy K S; Mansour H M; Khosravi M; Strawbridge H; Tobias J D
Description
An account of the resource
Background Lipid-laden macrophage (LLM) index could be potentially useful in assessing gastroesophageal (GE) reflux and aspiration after lung transplantation (LT) in patients with cystic fibrosis (CF). Methods A retrospective review of CF patients undergoing LT and/or laparoscopic Nissen fundoplication (LNF) from January 1, 2009, to December 31, 2011, was performed. Results Seventeen CF patients (nine women), mean (+/- SD) age 27.9 +/- 7.5 yr, underwent LT with mean (+/- SD) pre-transplant FEV1 of 20.9 +/- 5.0% predicted. Seventy percentage (12/17) of patients underwent LNF without complications within 12 wk of LT. After LT, but prior to antireflux surgery, there was no significant difference in the mean (+/- SD) baseline LLM index (154 +/- 41 vs. 146 +/- 51, p = NS) between patients who were to undergo LNF and patients who did not. After LNF, a significant reduction in the mean (+/- SD) LLM index occurred following the procedure (154 +/- 4174 +/- 54, p < 0.0001) while each patient reported resolution of symptoms of GE reflux, whereas 40% (2/5) undergoing only medical treatment reported resolution of symptoms. Conclusions Significant reduction in the LLM index occurred after LNF in CF patients after LT that correlated with resolution of clinical symptoms of GE reflux.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/ctr.12020" target="_blank" rel="noreferrer noopener">10.1111/ctr.12020</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2013
alveolar
Aspiration
association
bronchoalveolar lavage fluid
Children
chronic rejection
Clinical Transplantation
CYSTIC fibrosis
fat-embolism
gastroesophageal reflux
gastroesophageal-reflux disease
Hayes D
Journal Article or Conference Abstract Publication
Khosravi M
Kirkby S
Laparoscopic
lipid-laden macrophage index
Lung
Macrophages
Mansour H M
marker
McCoy K S
Nissen fundoplication
Oil Red O stain
pepsin
pulmonary aspiration
Strawbridge H
Surgery
Tobias J D
Transplantation
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajplung.00205.2003" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajplung.00205.2003</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
L679-L689
Issue
4
Volume
286
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Mechanisms Of Alveolar Protein Clearance In The Intact Lung
Publisher
An entity responsible for making the resource available
American Journal of Physiology-Lung Cellular and Molecular Physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-04
Subject
The topic of the resource
acute respiratory distress syndrome; air-blood barrier; apoprotein sp-a; bronchoalveolar lavage fluid; diffusion; endocytosis; epithelial-cell monolayers; ii cells; instillation; intratracheal; junctions; opens tight; perfused rabbit lungs; Physiology; protein; rat lung; Respiratory System; respiratory-distress syndrome; transport pulmonary edema
Creator
An entity primarily responsible for making the resource
Hastings R H; Folkesson H G; Matthay M A
Description
An account of the resource
Transport of protein across the alveolar epithelial barrier is a critical process in recovery from pulmonary edema and is also important in maintaining the alveolar milieu in the normal healthy lung. Various mechanisms have been proposed for clearing alveolar protein, including transport by the mucociliary escalator, intra-alveolar degradation, or phagocytosis by macrophages. However, the most likely processes are endocytosis across the alveolar epithelium, known as transcytosis, or paracellular diffusion through the epithelial barrier. This article focuses on protein transport studies that evaluate these two potential mechanisms in whole lung or animal preparations. When protein concentrations in the air spaces are low, e. g., albumin concentrations <0.5 g/100 ml, protein transport demonstrates saturation kinetics, temperature dependence indicating high energy requirements, and sensitivity to pharmacological agents that affect endocytosis. At higher concentrations, the protein clearance rate is proportional to protein concentration without signs of saturation, inversely related to protein size, and insensitive to endocytosis inhibition. Temperature dependence suggests a passive process. Based on these findings, alveolar albumin clearance occurs by receptor-mediated transcytosis at low protein concentrations but proceeds by passive paracellular mechanisms at higher concentrations. Because protein concentrations in pulmonary edema fluid are high, albumin concentrations of 5 g/100 ml or more, clearance of alveolar protein occurs by paracellular pathways in the setting of pulmonary edema. Transcytosis may be important in regulating the alveolar milieu under nonpathological circumstances. Alveolar degradation may become important in long-term protein clearance, clearance of insoluble proteins, or under pathological conditions such as immune reactions or acute lung injury.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajplung.00205.2003" target="_blank" rel="noreferrer noopener">10.1152/ajplung.00205.2003</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2004
acute respiratory distress syndrome
air-blood barrier
American Journal of Physiology-Lung Cellular and Molecular Physiology
apoprotein sp-a
bronchoalveolar lavage fluid
diffusion
Endocytosis
epithelial-cell monolayers
Folkesson H G
Hastings R H
ii cells
instillation
Intratracheal
Journal Article or Conference Abstract Publication
junctions
Matthay M A
opens tight
perfused rabbit lungs
Physiology
Protein
rat lung
Respiratory System
respiratory-distress syndrome
transport pulmonary edema