1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1586/14787210.2015.1018825" target="_blank" rel="noreferrer noopener">http://doi.org/10.1586/14787210.2015.1018825</a> Pages 405–407 Issue 4 Volume 13 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Is combination therapy for carbapenem-resistant Klebsiella pneumoniae the new standard of care? Publisher An entity responsible for making the resource available Expert review of anti-infective therapy Date A point or period of time associated with an event in the lifecycle of the resource 2015 2015-04 Subject The topic of the resource Humans; Randomized Controlled Trials as Topic; Anti-Bacterial Agents/*therapeutic use; beta-Lactam Resistance/genetics; carbapenem-resistant Klebsiella pneumoniae; Carbapenems/*therapeutic use; combination antibiotic therapy; Klebsiella Infections/*drug therapy/microbiology; Klebsiella pneumoniae/*drug effects/genetics/pathogenicity; Drug Therapy; Combination/*statistics & numerical data Creator An entity primarily responsible for making the resource Watkins Richard R; Deresinski Stan Description An account of the resource Carbapenem-resistant Klebsiella pneumoniae causes serious nosocomial infections and therapeutic options are limited. There is increasing evidence suggesting that combination antibiotic therapy is more effective than monotherapy and leads to better outcomes. However, questions remain about which regimen is optimal and how to balance the potential benefits of combination therapy versus the risks and possible complications (e.g., toxicity, increased costs, Clostridium difficile infection). Well-designed randomized clinical trials are needed to clarify these issues. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1586/14787210.2015.1018825" target="_blank" rel="noreferrer noopener">10.1586/14787210.2015.1018825</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). 2015 Anti-Bacterial Agents/*therapeutic use beta-Lactam Resistance/genetics carbapenem-resistant Klebsiella pneumoniae Carbapenems/*therapeutic use combination antibiotic therapy Combination/*statistics & numerical data Department of Internal Medicine Deresinski Stan Drug Therapy Expert review of anti-infective therapy Humans Klebsiella Infections/*drug therapy/microbiology Klebsiella pneumoniae/*drug effects/genetics/pathogenicity NEOMED College of Medicine Randomized Controlled Trials as Topic Watkins Richard R