Incidence Of Staphylococcus Aureus Nasal Colonization And Soft Tissue Infection Among High School Football Players
Athlete; carriage; community; epidemiology; General & Internal Medicine; healthy-children; MRSA; outbreak; population; prevalence; risk-factors; skin; Skin Infection; team
Background: Methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections have been documented with increasing frequency in both team and individual sports in recent years. It also seems that the level of MRSA skin and soft tissue infections in the general population has increased. Methods: One hundred ninety athletes from 6 local high school football teams were recruited for this prospective observational study to document nasal colonization and the potential role this plays in skin and soft tissue infections in football players and, in particular, MRSA infections. Athletes had nasal swabs done before their season started, and they filled out questionnaires regarding potential risk factors for skin and soft tissue infections. Those enrolled in the study were then observed over the course of the season for skin and soft tissue infections. Those infected had data about their infections collected. Results: One hundred ninety of 386 available student athletes enrolled in the study. Forty-four of the subjects had nasal colonization with methicillin-susceptible S. aureus, and none were colonized with MRSA. There were 10 skin and soft tissue infections (8 bacterial and 2 fungal) documented over the course of the season. All were treated as outpatients with oral or topical antibiotics, and none were considered serious. Survey data from the preseason questionnaire showed 21% with skin infection, 11% with methicillin-susceptible S. aureus, and none with MRSA infection during the past year. Three reported a remote history of MRSA infection. Conclusions: We documented an overall skin infection rate of 5.3% among high school football players over a single season. Our results suggest that skin and soft tissue infection may not be widespread among high school athletes in northeast Ohio. (J Am Board Fam Med 2011;24:429-435.)
Lear A; McCord G; Peiffer J; Watkins R R; Parikh A; Warrington S
Journal of the American Board of Family Medicine
2011
2011-07
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.3122/jabfm.2011.04.100286" target="_blank" rel="noreferrer noopener">10.3122/jabfm.2011.04.100286</a>
Shorter Course Therapy Of Serious Respiratory Infections: New Data For New Approaches To Management
adults; antibiotic-therapy; carriage; Infectious Diseases; meningococcal disease; randomized-trial; resolution; ventilator-associated pneumonia
File T M
Current Opinion in Infectious Diseases
2004
2004-04
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1097/10.qco.0000124363.27345.46" target="_blank" rel="noreferrer noopener">10.1097/10.qco.0000124363.27345.46</a>
Hospital Readmissions in Patients With Carbapenem-Resistant Klebsiella pneumoniae
outcomes; epidemiology; therapy; Infectious Diseases; metaanalysis; Environmental & Occupational Health; Public; efficacy; carriage; enterobacteriaceae; outbreak; emergence; tigecycline
BACKGROUND. Various transmission routes contribute to spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) in hospitalized patients. Patients with readmissions during which CRKP is again isolated ("CRKP readmission") potentially contribute to transmission of CRKP. OBJECTIVE. To evaluate CRKP readmissions in the Consortium on Resistance against Carbapenems in K. pneumoniae (CRaCKLe). DESIGN. Cohort study from December 24, 2011, through July 1, 2013. SETTING. Multicenter consortium of acute care hospitals in the Great Lakes region. PATIENTS. All patients who were discharged alive during the study period were included. Each patient was included only once at the time of the first CRKP-positive culture. METHODS. All readmissions within 90 days of discharge from the index hospitalization during which CRKP was again found were analyzed. Risk factors for CRKP readmission were evaluated in multivariable models. RESULTS. Fifty-six (20%) of 287 patients who were discharged alive had a CRKP readmission. History of malignancy was associated with CRKP readmission (adjusted odds ratio [adjusted OR], 3.00 [95% CI, 1.32-6.65], P<.01). During the index hospitalization, 160 patients (56%) received antibiotic treatment against CRKP; the choice of regimen was associated with CRKP readmission (P=.02). Receipt of tigecycline-based therapy (adjusted OR, 5.13 [95% CI, 1.72-17.44], using aminoglycoside-based therapy as a reference in those treated with anti-CRKP antibiotics) was associated with CRKP readmission. CONCLUSION. Hospitalized patients with CRKP specifically those with a history of malignancy are at high risk of readmission with recurrent CRKP infection or colonization. Treatment during the index hospitalization with a tigecycline-based regimen increases this risk.
Messina J A; Cober E; Richter S S; Perez F; Salata R A; Kalayjian R C; Watkins R; Scalera N M; Doi Y H; Kaye K S; Evans S; Bonomo R A; Fowler V G; van Duin D; Antibacterial Resistance Leadershi
Infection Control and Hospital Epidemiology
2016
2016-03
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1017/ice.2015.298" target="_blank" rel="noreferrer noopener">10.1017/ice.2015.298</a>
Perianal versus anorectal specimens: Is there a difference in group B streptococcal detection?
carriage; disease; Obstetrics & Gynecology; pregnancy; prevention
OBJECTIVE: To investigate whether specimens obtained from the perianal area have a Group B streptococcal culture detection rate similar to anorectal specimens. METHODS: This is a prospective cohort study at a tertiary care university-affiliated teaching hospital. A total of 136 pregnant women between 33 and 40 weeks' gestation were recruited. Three samples for Group B streptococcal culture detection were obtained from each subject in the following order: perianal sample, vaginoperianal sample, and an anorectal sample. The women were asked to rank their pain or discomfort with obtaining the anorectal sample. The vaginoperianal specimen is the standard sample obtained from antepartum patients in this clinic, and, therefore, it serves as the control. RESULTS: Of the 136 subjects, 26.5% of the control, vaginoperianal samples were positive for Group B streptococcal culture. In comparison, 27.2% of the anorectal specimens and 28.7% of the perianal specimens were positive for Group B streptococcal. culture. There was no statistically significant difference in the detection of Group B streptococcal culture among the three sample sites. Evaluation of the pain experienced with an anorectal sampling showed that 68% of subjects ranked their pain between mild to moderate, and 5% noted severe pain. CONCLUSION: The Group B streptococcal detection rate was not different among the three sampling sites. Therefore, pregnant women do not need to be subjected to the additional pain of anorectal sampling to detect Group B Streptococcus. (Obstet Gynecol 2002;99:1036-9. (C) 2002 by the American College of Obstetricians and Gynecologists).
Orafu C; Gill P; Nelson K; Hecht B; Hopkins M
Obstetrics and Gynecology
2002
2002-06
Journal Article
<a href="http://doi.org/10.1016/s0029-7844(02)01979-8" target="_blank" rel="noreferrer noopener">10.1016/s0029-7844(02)01979-8</a>