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Text
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URL Address
<a href="http://doi.org/10.3810/pgm.1999.03.656" target="_blank" rel="noreferrer noopener">http://doi.org/10.3810/pgm.1999.03.656</a>
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Pages
229-+
Issue
3
Volume
105
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Dublin Core
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Title
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A palpable clue to vasculitis
Publisher
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Postgraduate Medicine
Date
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1999
1999-03
Subject
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General & Internal Medicine; colchicine; cutaneous leukocytoclastic vasculitis
Creator
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Arvan M E; Brodell R T
Description
An account of the resource
A 57-year-old woman presented with a rash on her legs that had recurred several times over the last 2 weeks. Initial treatment consisted of prednisone, 30 mg/day, for 5 days, but the rash had recurred when therapy was discontinued. Laboratory findings at that time revealed an elevated antistreptolysin O titer, but a complete blood cell (CBC) count, electrolyte levels, erythrocyte sedimentation rate (ESR), and complement fixation test all were normal. The patient was subsequently given amoxicillin, which she discontinued after a few days when the rash worsened. Findings on physical examination were normal except for a palpable purpuric rash on the lower legs (figure 1). A 4-mm punch biopsy was performed, and histopathologic examination confirmed a diagnosis of leukocytoclastic vasculitis. The patient was given prednisone, 60 mg/day orally, tapered over 2 weeks. Erythromycin was also prescribed for the possible persistence of a streptococcal carrier state. The rash cleared within 2 to 3 weeks, with no recurrence during the following year.
Identifier
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<a href="http://doi.org/10.3810/pgm.1999.03.656" target="_blank" rel="noreferrer noopener">10.3810/pgm.1999.03.656</a>
Format
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Journal Article or Conference Abstract Publication
1999
Arvan M E
Brodell R T
colchicine
cutaneous leukocytoclastic vasculitis
General & Internal Medicine
Journal Article or Conference Abstract Publication
Postgraduate medicine