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Text
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URL Address
<a href="http://doi.org/10.7759/cureus.1804" target="_blank" rel="noreferrer noopener">http://doi.org/10.7759/cureus.1804</a>
Pages
e1804–e1804
Issue
10
Volume
9
Dublin Core
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Title
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Topiramate-Induced Lithium Toxicity.
Publisher
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Cureus
Date
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2017
2017-10
Subject
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binge eating disorder; compulsive urge of food intake; lithium toxicitiy; schizoaffective disorder bipolar type 1; topiramate
Creator
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Khan Afaque H; Shah Shazia Q
Description
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This case report discusses a suspected case of lithium toxicity following the administration of topiramate (TPM). Our patient is a 47-year-old man who has been an inpatient for the past year and was diagnosed with schizoaffective disorder bipolar type 1 for the past 20 years according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). He manifested symptoms of lithium toxicity following administration of TPM to ameliorate the compulsive consumption of food and liquids. The patient was already being treated with lithium carbonate for mania, labile mood, and aggressive behavior for the past year. The patient developed symptoms of lithium toxicity on the fourth day of the TPM treatment. We transferred the patient to the emergency department where he was diagnosed and treated for renal insufficiency due to lithium toxicity. After halting the TPM and reintroducing lithium carbonate, the patient's laboratory results improved. This case illustrates the potential toxic interaction of medications with a narrow therapeutic index like lithium.
Identifier
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<a href="http://doi.org/10.7759/cureus.1804" target="_blank" rel="noreferrer noopener">10.7759/cureus.1804</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
binge eating disorder
compulsive urge of food intake
Cureus
Khan Afaque H
lithium toxicitiy
schizoaffective disorder bipolar type 1
Shah Shazia Q
topiramate