Quantification of Liver Fat Content with Ultrasound: A WFUMB Position Paper.
The assessment of steatosis (liver fat content) is relevant in patients suspected of, or diagnosed with, chronic liver diseases. Steatosis is usually a diffuse process within the liver tissue, but a non-uniform distribution can sometimes be observed (focal fatty changes or zonal/regional steatosis, focal or segmental sparing).
New ultrasound methods that can be used to quantitatively assess liver fat content have recently been developed. These quantitative ultrasound (QUS) methods are based on the analysis of radiofrequency echoes detected by the transducer, allowing calculation of parameters for quantifying the fat in the liver. In this position paper, after a section dedicated to the importance of quantifying liver steatosis in patients with non-alcoholic fatty liver disease and another section dedicated to the assessment of liver fat with magnetic resonance, the current clinical studies performed using QUS are summarized. These new methods include spectral-based techniques and techniques based on envelope statistics. The spectral-based techniques that have been used in clinical studies are those estimating the attenuation coefficient and those estimating the backscatter coefficient. Clinical studies that have used tools based on the envelope statistics of the backscattered ultrasound are those performed by using the acoustic structure quantification or other parameters derived from it, such as the normalized local variance, and that performed by estimating the speed of sound. Experts’ opinions are reported.
Ferraioli G; Berzigotti A; Barr RG; Choi BI; Cui XW; Dong Y; Gilja OH; Lee JY; Lee DH; Moriyasu F; Piscaglia F; Sugimoto K; Wong GL; Wong VW; Dietrich CF
Ultrasound in Medicine & Biology
2021
2021-08-24
38; Biology. All rights reserved.
Journal Article
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Quantification of Liver Fat Content with Ultrasound: A WFUMB Position Paper.
Attenuation coefficient; Backscatter; Controlled attenuation parameter; Dispersion; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Quantitative ultrasound; Speed of sound
New ultrasound methods that can be used to quantitatively assess liver fat content have recently been developed. These quantitative ultrasound (QUS) methods are based on the analysis of radiofrequency echoes detected by the transducer, allowing calculation of parameters for quantifying the fat in the liver. In this position paper, after a section dedicated to the importance of quantifying liver steatosis in patients with non-alcoholic fatty liver disease and another section dedicated to the assessment of liver fat with magnetic resonance, the current clinical studies performed using QUS are summarized. These new methods include spectral-based techniques and techniques based on envelope statistics. The spectral-based techniques that have been used in clinical studies are those estimating the attenuation coefficient and those estimating the backscatter coefficient. Clinical studies that have used tools based on the envelope statistics of the backscattered ultrasound are those performed by using the acoustic structure quantification or other parameters derived from it, such as the normalized local variance, and that performed by estimating the speed of sound. Experts' opinions are reported. (Copyright © 2021 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.)
Ferraioli G; Berzigotti A; Barr RG; Choi BI; Cui XW; Dong Y; Gilja OH; Lee JY; Lee DH; Moriyasu F; Piscaglia F; Sugimoto K; Wong GL; Wong VW; Dietrich CF
Ultrasound in Medicine & Biology
2021
2021-07-17
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
journalArticle
<a href="http://doi.org/10.1016/j.ultrasmedbio.2021.06.002" target="_blank" rel="noreferrer noopener">10.1016/j.ultrasmedbio.2021.06.002</a>
Conventional ultrasound for diagnosis of hepatic steatosis is better than believed
fibrosis; conventional ultrasound; cirrhosis; hepatic steatosis; nonalcoholic fatty liver disease; METABOLIC SYNDROME; ABDOMINAL ULTRASOUND; ARTERY RESISTIVE INDEX; CONTROLLED ATTENUATION PARAMETER; DOPPLER WAVE-FORM; HEPATORENAL INDEX; NAFLD FIBROSIS SCORE; NONALCOHOLIC FATTY LIVER; NONINVASIVE ASSESSMENT; VEIN DOPPLER
Zusammenfassung
Dietrich CF; Shi L; Lowe A; Dong Y; Potthoff A; Sparchez Z; Teufel A; Guth S; Koch J; Barr RG; Cui XW
Zeitschrift Fur Gastroenterologie
2021
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
journalArticle
<a href="http://doi.org/10.1055/a-1491-1771" target="_blank" rel="noreferrer noopener">10.1055/a-1491-1771</a>
Liver Ultrasound Elastography: An Update To The World Federation For Ultrasound In Medicine And Biology Guidelines And Recommendations
Acoustic radiation; Acoustics; acting antiviral therapy; controlled attenuation parameter; Elastography; Elastography; Focal liver lesions; force impulse; hepatitis-c virus; hypertension; liver; Liver diseases; Liver fibrosis; Liver stiffness; noninvasive assessment; Nuclear Medicine & Medical Imaging; Portal; portal-hypertension; radiation force impulse; Radiology; Shear wave elastography; shear-wave; significant; stiffness measurement; Strain elastography; time tissue elastography; Transient elastography; Transient elastography; ultrasound; World Federation for Ultrasound in Medicine and Biology guidelines
Ferraioli G; Wong V W S; Castera L; Berzigotti A; Sporea L; Dietrich C F; Choi B I; Wilson S R; Kudo M; Barr R G
Ultrasound in Medicine and Biology
2018
2018-12
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/j.ultrasmedbio.2018.07.008" target="_blank" rel="noreferrer noopener">10.1016/j.ultrasmedbio.2018.07.008</a>