1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.drugalcdep.2007.07.019" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.drugalcdep.2007.07.019</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
164-172
Issue
1
Volume
92
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Brain Macrostructural And Microstructural Abnormalities In Cocaine Dependence
Publisher
An entity responsible for making the resource available
Drug and Alcohol Dependence
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
2008-01
Subject
The topic of the resource
abstinent; abuse; addiction; alcohol; brain; chronic cerebral hypoperfusion; cocaine; dependence; diffusion tensor imaging (DTI); drug-abuse; gerbil brain; magnetic resonance imaging (MRI); prefrontal cortex; Psychiatry; schizophrenia; Substance Abuse; users; white-matter integrity
Creator
An entity primarily responsible for making the resource
Lim K O; Wozniak J R; Mueller B A; Franc D T; Specker S M; Rodriguez C P; Silverman A B; Rotrosen J P
Description
An account of the resource
Rationale: Two previous studies have utilized diffusion tensor imaging (DTI) to examine microstructural integrity in cocaine abuse and found 41 evidence of brain abnormalities in white matter. Objective: Using anatomical magnetic resonance imaging (MRI), DTI, and clinical evaluation, the macrostructural and microstructural correlates of cocaine abuse were investigated. Methods: Twenty-one men and women (mean age 42.5 and mean 18.9 years of cocaine use) and 21 age/gender-matched controls were included. Fractional anisotropy (FA) was measured in frontal white matter ROIs. Gray and white matter volumes in superior and inferior frontal regions were compared. Results: DTI data revealed that cocaine users had lower FA than controls, specifically in inferior frontal white matter. FA differences were not seen in other areas. Significant volumetric differences were not seen, but both gray and white matter inferior frontal volumes trended toward smaller in the cocaine group. The data suggested that duration of use was associated with decreased gray and white matter volumes. FA and gray matter volume were correlated in cocaine users. Conclusions: Both macrostructural and microstructural abnormalities were seen in a group of cocaine abusers. Length of cocaine use was associated with severity of the brain abnormalities. Future studies of white matter tissue integrity are warranted including examination of the relationship between DTI measures and traditional volumetric measures. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.drugalcdep.2007.07.019" target="_blank" rel="noreferrer noopener">10.1016/j.drugalcdep.2007.07.019</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2008
abstinent
abuse
Addiction
Alcohol
Brain
chronic cerebral hypoperfusion
Cocaine
dependence
diffusion tensor imaging (DTI)
Drug and Alcohol Dependence
drug-abuse
Franc D T
gerbil brain
Journal Article or Conference Abstract Publication
Lim K O
magnetic resonance imaging (MRI)
Mueller B A
prefrontal cortex
Psychiatry
Rodriguez C P
Rotrosen J P
Schizophrenia
Silverman A B
Specker S M
Substance Abuse
users
white-matter integrity
Wozniak J R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1037/adb0000262" target="_blank" rel="noreferrer noopener">http://doi.org/10.1037/adb0000262</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
326-335
Issue
3
Volume
31
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The Association Between Daily Ptsd Symptom Severity And Alcohol-related Outcomes In Recent Traumatic Injury Victims
Publisher
An entity responsible for making the resource available
Psychology of Addictive Behaviors
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-05
Subject
The topic of the resource
alcohol; college-students; combat veterans; dependence; drinking; experience sampling; functional outcomes; hospitalization; interventions; posttraumatic stress disorder (PTSD); posttraumatic stress disorder (PTSD); prolonged exposure; Psychology; Substance Abuse; traumatic injury; us
Creator
An entity primarily responsible for making the resource
Hruska B; Pacella M L; George R L; Delahanty D L
Description
An account of the resource
The self-medication hypothesis proposes that individuals experiencing posttraumatic stress disorder (PTSD) symptoms may use alcohol (or other substances) to self-medicate distress, while the mutual maintenance hypothesis proposes that alcohol use also exacerbates or maintains distress. Existing research largely supports the self-medication hypothesis. However, findings are often based upon retrospective reporting of problems and assessment of symptoms anchored to a trauma occurring in the remote past. To improve on these retrospective designs, the current study examined the relationship between daily PTSD symptom severity and alcohol-related outcomes during the early phase of recovery following a traumatic physical injury. Specifically, 36 injury victims reported on PTSD symptom severity, alcohol craving, alcohol consumption, and negative drinking consequences thrice daily (morning, afternoon, night) over 7 days beginning 6 weeks postinjury. Results indicated relationships between PTSD symptom severity and alcohol craving/negative consequences when these experiences were assessed concurrently within the same signal (particularly during the nighttime assessments). Prospective models found that nighttime PTSD symptom severity was related to negative drinking consequences occurring the following morning, even after controlling for consumption level, suggesting a more general behavioral regulation problem. Results were less supportive of the mutual maintenance hypothesis. Collectively, these results suggest that health interventions targeting PTSD symptom severity in recent injury victims-particularly when delivered at night-may be able to prevent problematic alcohol use.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1037/adb0000262" target="_blank" rel="noreferrer noopener">10.1037/adb0000262</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2017
Alcohol
college-students
combat veterans
Delahanty D L
dependence
drinking
experience sampling
functional outcomes
George R L
Hospitalization
Hruska B
interventions
Journal Article or Conference Abstract Publication
Pacella M L
posttraumatic stress disorder (PTSD)
Prolonged exposure
Psychology
Psychology of Addictive Behaviors
Substance Abuse
traumatic injury
us
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0024-3205(96)00222-6" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0024-3205(96)00222-6</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
PL345-PL352
Issue
24
Volume
58
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Place Preference And Microdialysis Studies With Two Derivatives Of Methylphenidate
Publisher
An entity responsible for making the resource available
Life Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
1996-05
Subject
The topic of the resource
abuse; affinity; binding; cocaine; dependence; dopamine; methylphenidate; microdialysis studies; pharmacology; Pharmacology & Pharmacy; place preference; Research & Experimental Medicine; transporters
Creator
An entity primarily responsible for making the resource
Gatley S J; Meehan S M; Chen R; Pan D F; Schechter M D; Dewey S L
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0024-3205(96)00222-6" target="_blank" rel="noreferrer noopener">10.1016/0024-3205(96)00222-6</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1996
abuse
Affinity
Binding
Chen R
Cocaine
dependence
Dewey S L
Dopamine
Gatley S J
Life sciences
Meehan S M
methylphenidate
microdialysis studies
Pan D F
pharmacology
Pharmacology & Pharmacy
place preference
Research & Experimental Medicine
Schechter M D
transporters