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40
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Hyperlink
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URL
https://doi.org/10.1111/brv.12791
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology
Creator
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Rochelle Buffenstein
Vincent Amoroso
Blazej Andziak
Stanislav Avdieiev
Jorge Azpurua
Alison J Barker
Nigel C Bennett
Miguel A Brieño-Enríquez
Gary N Bronner
Clive Coen
Martha A Delaney
Christine M Dengler-Crish
Yael H Edrey
Chris G Faulkes
Daniel Frankel
Gerard Friedlander
Patrick A Gibney
Vera Gorbunova
Christopher Hine
Melissa M Holmes
Jennifer U M Jarvis
Yoshimi Kawamura
Nobuyuki Kutsukake
Cynthia Kenyon
Walid T Khaled
Takefumi Kikusui
Joseph Kissil
Samantha Lagestee
John Larson
Amanda Lauer
Leonid A Lavrenchenko
Angela Lee
Jonathan B Levitt
Gary R Lewin
Kaitlyn N Lewis Hardell
TzuHua D Lin
Matthew J Mason
Dan McCloskey
Mary McMahon
Kyoko Miura
Kazutaka Mogi
Vikram Narayan
Timothy P O'Connor
Kazuo Okanoya
M Justin O'Riain
Thomas J Park
Ned J Place
Katie Podshivalova
Matthew E Pamenter
Sonja J Pyott
Jane Reznick
J Graham Ruby
Adam B Salmon
Joseph Santos-Sacchi
Diana K Sarko
Andrei Seluanov
Alyssa Shepard
Megan Smith
Kenneth B Storey
Xiao Tian
Emily N Vice
Mélanie Viltard
Akiyuki Watarai
Ewa Wywial
Masanori Yamakawa
Elena D Zemlemerova
Michael Zions
Ewan St John Smith
Date
A point or period of time associated with an event in the lifecycle of the resource
2022
Description
An account of the resource
The naked mole-rat (Heterocephalus glaber) has fascinated zoologists for at least half a century. It has also generated considerable biomedical interest not only because of its extraordinary longevity, but also because of unusual protective features (e.g. its tolerance of variable oxygen availability), which may be pertinent to several human disease states, including ischemia/reperfusion injury and neurodegeneration. A recent article entitled 'Surprisingly long survival of premature conclusions about naked mole-rat biology' described 28 'myths' which, those authors claimed, are a 'perpetuation of beautiful, but falsified, hypotheses' and impede our understanding of this enigmatic mammal. Here, we re-examine each of these 'myths' based on evidence published in the scientific literature. Following Braude et al., we argue that these 'myths' fall into four main categories: (i) 'myths' that would be better described as oversimplifications, some of which persist solely in the popular press; (ii) 'myths' that are based on incomplete understanding, where more evidence is clearly needed; (iii) 'myths' where the accumulation of evidence over the years has led to a revision in interpretation, but where there is no significant disagreement among scientists currently working in the field; (iv) 'myths' where there is a genuine difference in opinion among active researchers, based on alternative interpretations of the available evidence. The term 'myth' is particularly inappropriate when applied to competing, evidence-based hypotheses, which form part of the normal evolution of scientific knowledge. Here, we provide a comprehensive critical review of naked mole-rat biology and attempt to clarify some of these misconceptions.
Source
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Biol Rev Camb Philos Soc
. 2022 Feb;97(1):115-140. doi: 10.1111/brv.12791. Epub 2021 Sep 3.
Language
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English
2022
ageing
Cancer
ecology
eusociality
hypoxia
longevity
naked mole-rat
nociception
thermoregulation.
-
Text
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URL Address
<a href="http://doi.org/10.1002/ece3.6224" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ece3.6224</a>
ISSN
2045-7758
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1002/ece3.6224" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1002/ece3.6224</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
June 2020 Update II
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Anatomy & Neurobiology
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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What smells? Developing in-field methods to characterize the chemical composition of wild mammalian scent cues
Publisher
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Ecology and Evolution
Subject
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behavior; callithrix-jacchus; chemical ecology; ecology; fruit odor; marking; Marmoset; odor; olfactory cues; portable GC-MS; scent marking; Sex; signals; signatures
Creator
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Thompson Cynthia L; Bottenberg Kimberly N; Lantz Andrew W; de Oliveira Maria A B; Melo Leonardo C O; Vinyard Christopher J
Description
An account of the resource
Olfactory cues play an important role in mammalian biology, but have been challenging to assess in the field. Current methods pose problematic issues with sample storage and transportation, limiting our ability to connect chemical variation in scents with relevant ecological and behavioral contexts. Real-time, in-field analysis via portable gas chromatography-mass spectrometry (GC-MS) has the potential to overcome these issues, but with trade-offs of reduced sensitivity and compound mass range. We field-tested the ability of portable GC-MS to support two representative applications of chemical ecology research with a wild arboreal primate, common marmoset monkeys (Callithrix jacchus). We developed methods to (a) evaluate the chemical composition of marmoset scent marks deposited at feeding sites and (b) characterize the scent profiles of exudates eaten by marmosets. We successfully collected marmoset scent marks across several canopy heights, with the portable GC-MS detecting known components of marmoset glandular secretions and differentiating these from in-field controls. Likewise, variation in the chemical profile of scent marks demonstrated a significant correlation with marmoset feeding behavior, indicating these scents' biological relevance. The portable GC-MS also delineated species-specific olfactory signatures of exudates fed on by marmosets. Despite the trade-offs, portable GC-MS represents a viable option for characterizing olfactory compounds used by wild mammals, yielding biologically relevant data. While the decision to adopt portable GC-MS will likely depend on site- and project-specific needs, our ability to conduct two example applications under relatively challenging field conditions bodes well for the versatility of in-field GC-MS.
Identifier
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<a href="http://doi.org/10.1002/ece3.6224" target="_blank" rel="noreferrer noopener">10.1002/ece3.6224</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
Behavior
Bottenberg Kimberly N
callithrix-jacchus
chemical ecology
de Oliveira Maria A B
Department of Anatomy & Neurobiology
ecology
Ecology and Evolution
fruit odor
journalArticle
June 2020 Update II
Lantz Andrew W
marking
Marmoset
Melo Leonardo C O
NEOMED College of Medicine
odor
olfactory cues
portable GC-MS
Scent marking
sex
signals
signatures
Thompson Cynthia L
Vinyard Christopher J
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1370/afm.220" target="_blank" rel="noreferrer noopener">http://doi.org/10.1370/afm.220</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
333-340
Issue
4
Volume
2
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Patient Reports Of Preventable Problems And Harms In Primary Health Care
Publisher
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Annals of Family Medicine
Date
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2004
2004-07
Subject
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adverse events; ecology; General & Internal Medicine; harms; health care; medical errors; patient perspective; patient safety; patient-centered care; physician-patient relations; physicians; qualitative research; quality; quality assurance; safety
Creator
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Kuzel A J; Woolf S H; Gilchrist V J; Engel J D; LaVeist T A; Vincent C; Frankel R M
Description
An account of the resource
BACKGROUND Despite recent attention given to medical errors, little is known about the kinds and importance of medical errors in primary care. The principal aims of this study were to develop patient-focused typologies of medical errors and harms in primary care settings and to discern which medical errors and harms seem to be the most important. METHODS Thirty-eight in-depth anonymous interviews of adults from rural, suburban, and urban locales in Virginia and Ohio were conducted to solicit stories of preventable problems with primary health care that led to physical or psychological harm. Transcriptions were analyzed to identify, name, and organize the stories of errors and harms. RESULTS The 38 narratives described 221 problematic incidents that predominantly involved breakdowns in the clinician-patient relationship (n = 82, 37%) and access to clinicians (n = 63, 29%). There were several reports of perceived racism. The incidents were linked to 170 reported harms, 70% of which were psychological, including anger, frustration, belittlement, and loss of relationship and trust in one's clinician. Physical harms accounted for 23% of the total and included pain, bruising, worsening medical condition, and adverse drug reactions. DISCUSSION The errors reported by interviewed patients suggest that breakdowns in access to and relationships with clinicians may be more prominent medical errors than are technical errors in diagnosis and treatment. Patients were more likely to report being harmed psychologically and emotionally, suggesting that the current preoccupation of the patient safety movement with adverse drug events and surgical mishaps could overlook other patient priorities.
Identifier
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<a href="http://doi.org/10.1370/afm.220" target="_blank" rel="noreferrer noopener">10.1370/afm.220</a>
Format
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Journal Article or Conference Abstract Publication
2004
adverse events
Annals of family medicine
ecology
Engel J D
Frankel R M
General & Internal Medicine
Gilchrist V J
harms
Health Care
Journal Article or Conference Abstract Publication
Kuzel A J
LaVeist T A
Medical Errors
patient perspective
Patient Safety
Patient-Centered Care
Physician-Patient Relations
Physicians
Qualitative Research
quality
Quality Assurance
Safety
Vincent C
Woolf S H