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Text
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<a href="http://doi.org/10.1097/01.yct.0000244238.17791.a4" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/01.yct.0000244238.17791.a4</a>
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Pages
243-246
Issue
4
Volume
22
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Title
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A retrospective comparison of anesthetic agents in electroconvulsive therapy
Publisher
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Journal of Ect
Date
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2006
2006-12
Subject
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anesthetics; Behavioral Sciences; ect; electroconvulsive therapy; methohexital; propofol; Psychiatry; thiopental
Creator
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Swaim J C; Mansour M; Wydo S M; Moore J L
Description
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A recent lack of availability of the anesthetic agent methohexital in the United States allowed for a naturalistic study of the efficacy and the adverse effects of alternatives. Methohexital, propofol, and thiopental were compared as anesthetic agents for electroconvulsive therapy in 95 patients treated during a 23-month period in a general public hospital. Missed seizures and arrhythmias were infrequently observed (< 4% for any agent). Methohexital was found significantly related to longer seizure durations in comparison with both other agents (P < 0.01). The use of propofol was associated with increased risk of missed seizure (8.9%) compared with methohexital (3.9%) and thiopental (3.2%). Propofol was also associated with higher doses of administered energy, with a statistically significant difference (P = 0.018) observed between propofol and thiopental. Although propofol required the greatest energy delivery, it was associated with the shortest seizure durations. Methohexital resulted in the longest seizure duration, and thiopental was associated with the least amount of energy delivery with an intermediate seizure length.
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<a href="http://doi.org/10.1097/01.yct.0000244238.17791.a4" target="_blank" rel="noreferrer noopener">10.1097/01.yct.0000244238.17791.a4</a>
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Journal Article
2006
Anesthetics
Behavioral Sciences
ect
electroconvulsive therapy
Journal Article
Journal of Ect
Mansour M
methohexital
Moore J L
propofol
Psychiatry
Swaim J C
thiopental
Wydo S M