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Text
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URL Address
<a href="http://doi.org/10.7759/cureus.9498" target="_blank" rel="noreferrer noopener">http://doi.org/10.7759/cureus.9498</a>
Pages
e9498
Issue
7
Volume
12
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Update Year & Number
August 2020 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Mercy Health St Elizabeth Youngstown Hospital
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Title
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An unusual case of evolving localized tetanus despite prior immunization and protective antibody titer
Publisher
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Cureus
Date
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2020
2020-07-31
Subject
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vaccination; immunization; persistence; decennial booster; evolving tetanus; localized tetanus; protective antibody titer; tetanus titer
Creator
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Tharu B; Ibrahim S; Shah M; Basnet S; Park T
Description
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Centers for Disease Control and Prevention has reported that tetanus infection in a fully immunized person with the last dose within 10 years is extremely rare. The prevalence of localized tetanus in such a scenario is unknown. Only two case reports of localized tetanus in previously immunized patients have been reported so far, making this the third one. Also, this is the first case of its kind to demonstrate evolving localized tetanus. Our patient is a 19-year-old man who presented with shortness of breath, pain in right upper extremity, shoulder, and neck. His chest X-ray and creatine kinase were normal. The patient was sent home. He presented again to our hospital two days later with difficulty swallowing and speaking as well as chest tightness. Routine blood tests, electrocardiogram, CT angiography of the chest, and transthoracic echocardiogram were normal. He gave a history of a cut in the right middle finger while removing the carpet a week before his presentation. His immunization history was complete with documented last tetanus shot nine years and two months ago. He was treated with tetanus vaccine and penicillin. His tetanus antitoxoid titer came out protective.
Identifier
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<a href="http://doi.org/10.7759/cureus.9498" target="_blank" rel="noreferrer noopener">10.7759/cureus.9498</a>
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journalArticle
2020
August 2020 List
Basnet S
Cureus
decennial booster
Department of Internal Medicine
evolving tetanus
Ibrahim S
Immunization
journalArticle
localized tetanus
Mercy Health St Elizabeth Youngstown Hospital
NEOMED College of Medicine
Park T
Persistence
protective antibody titer
Shah M
tetanus titer
Tharu B
vaccination