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Text
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URL Address
<a href="http://doi.org/10.1016/s0361-9230(96)00268-7" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0361-9230(96)00268-7</a>
Pages
297–302
Issue
4
Volume
42
Dublin Core
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Title
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The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.
Publisher
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Brain research bulletin
Date
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1997
1905-06
Subject
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alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/*pharmacology; Animals; Anticonvulsants/*pharmacology; Electrophysiology; gamma-Aminobutyric Acid/*pharmacology; Hippocampus/*drug effects/physiology; Inbred Strains; Male; N-Methylaspartate/*pharmacology; Phenobarbital/pharmacology; Phenytoin/pharmacology; Rats; Valproic Acid/pharmacology
Creator
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Ko G Y; Brown-Croyts L M; Teyler T J
Description
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The effects of phenobarbital, phenytoin, and valproic acid on pharmacologically isolated NMDA-EPSP, AMPA-EPSP, and GABA-IPSPs were examined in rat hippocampal slices. Phenobarbital (0.05 mg/ml) had no effect on the NMDA-EPSP, but decreased the slope of the AMPA-EPSP by 13.4% and facilitated the GABA-IPSP slope by 77.12%. Phenytoin (0.02 mg/ml) had no effects on the NMDA-EPSP, AMPA-EPSP, or
Identifier
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<a href="http://doi.org/10.1016/s0361-9230(96)00268-7" target="_blank" rel="noreferrer noopener">10.1016/s0361-9230(96)00268-7</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1997
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/*pharmacology
Animals
Anticonvulsants/*pharmacology
Brain research bulletin
Brown-Croyts L M
Electrophysiology
gamma-Aminobutyric Acid/*pharmacology
Hippocampus/*drug effects/physiology
Inbred Strains
Ko G Y
Male
N-Methylaspartate/*pharmacology
Phenobarbital/pharmacology
Phenytoin/pharmacology
Rats
Teyler T J
Valproic Acid/pharmacology