1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.emc.2016.04.012" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.emc.2016.04.012</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
649-+
Issue
3
Volume
34
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Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Altered Mental Status and Delirium
Publisher
An entity responsible for making the resource available
Emergency Medicine Clinics of North America
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-08
Subject
The topic of the resource
adults; Altered mental status; cognitive impairment; confusion assessment method; delirium; Dementia; Elderly; elderly-patients; Emergency Medicine; Emergency Medicine; emergency-department patients; haloperidol; intensive-care-unit; Length of Stay; Medical decision-making capacity; scale; screening tools
Creator
An entity primarily responsible for making the resource
Wilber S T; Ondrejka J E
Description
An account of the resource
Older patients who present to the emergency department frequently have acute or chronic alterations of their mental status, including their level of consciousness and cognition. Recognizing both acute and chronic changes in cognition are important for emergency physicians. Delirium is an acute change in attention, awareness, and cognition. Numerous life threatening conditions can cause delirium; therefore, prompt recognition and treatment are critical. The authors discuss an organized approach that can lead to a prompt diagnosis within the time constraints of the emergency department.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.emc.2016.04.012" target="_blank" rel="noreferrer noopener">10.1016/j.emc.2016.04.012</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2016
adults
Altered mental status
cognitive impairment
confusion assessment method
delirium
dementia
Elderly
elderly-patients
Emergency Medicine
Emergency medicine clinics of North America
emergency-department patients
haloperidol
intensive-care-unit
Journal Article
Length of Stay
Medical decision-making capacity
Ondrejka J E
scale
screening tools
Wilber S T
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s12640-010-9222-y" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s12640-010-9222-y</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
97-101
Issue
1
Volume
20
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The Styrene Metabolite, Phenylglyoxylic Acid, Induces Striatal-Motor Toxicity in the Rat: Influence of Dose Escalation/Reduction over Time
Publisher
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Neurotoxicity Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011-07
Subject
The topic of the resource
Dose variation; exposure; haloperidol; haloperidol; movements; Neurosciences & Neurology; striatum; Styrene Phenylglyoxylic acid; Vacuous chewing movements
Creator
An entity primarily responsible for making the resource
Terre'Blanche G; Heyer N; Bergh J J; Mienie L J; Van der Schyf C J; Harvey B H
Description
An account of the resource
Exposure to the industrial solvent, styrene, induces locomotor and cognitive dysfunction in rats, and parkinsonian-like manifestations in man. The antipsychotic, haloperidol (HP), well known to induce striatal toxicity in man and animals, and styrene share a common metabolic pathway yielding p-fluoro phenylglyoxylic acid and phenylglyoxylic acid (PGA), respectively. Using an exposure period of 30 days and the vacous chewing movement (VCM) model as an expression of striatal-motor toxicity, we found that incremental PGA dosing (220-400 mg/kg) significantly increased VCMs up to day 25, but decreased to control levels shortly after reaching maximum dose. However, a diminishing dose of PGA (400-200 mg/kg) did not evoke an immediate worsening of VCMs but precipitated a significant increase in VCMs following dosage reduction to 200 mg/kg on day 22. PGA exposure, therefore, compromises striatal-motor function that is especially sensitive to changes in exposure dose. Longer alternating dose exposure studies are needed to establish whether motor dysfunction is progressive in severity or longevity. These findings are of significance for the environmental toxicology of styrene in the chemical industry.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s12640-010-9222-y" target="_blank" rel="noreferrer noopener">10.1007/s12640-010-9222-y</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2011
Bergh J J
Dose variation
exposure
haloperidol
Harvey B H
Heyer N
Journal Article
Mienie L J
movements
Neurosciences & Neurology
Neurotoxicity research
striatum
Styrene Phenylglyoxylic acid
Terre'Blanche G
Vacuous chewing movements
Van der Schyf C J